The Pharmaceutical Research and Manufacturers of America (PhRMA) is a trade association that represents the pharmaceutical industry in the United States. The organization was founded in 1958 and is headquartered in Washington, D.C. PhRMA's members include pharmaceutical research and biotechnology companies that are involved in the discovery and development of new medicines and vaccines. The organization advocates for policies that promote innovation and patient access to new treatments, and it works to educate policymakers and the public about the value of the pharmaceutical industry. PhRMA is also involved in efforts to combat the opioid epidemic and to promote responsible use of prescription drugs.