Nuwellis, Inc. is a medical device company that is focused on developing and commercializing innovative products for the treatment of patients with acute kidney injury (AKI) and other critical care conditions. The company's lead product, the Aquadex SmartFlow System, is a novel, ultrafiltration system that is designed to remove excess fluid from patients with AKI and other fluid overload conditions. The Aquadex SmartFlow System is a simple, easy-to-use, and cost-effective alternative to traditional methods of fluid removal, such as diuretics and dialysis. Nuwellis, Inc. was founded in 2019 and is headquartered in San Diego, California.