Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Software Engineer, Toast Delivery Services
$159K - $254K *
Drive impactful software development to enhance customer delivery experiences. Collaborate with cross-functional teams to design resilient systems that support real-time order tracking and efficient p...
Reposted 3 days ago
Senior Software Engineer Aerial Platform
$184K - $356K *
Shape the future of wireless communication by leading the development of cutting-edge 5G/6G systems. Collaborate with cross-functional teams to optimize performance and scalability, driving innovation...
1 week ago
$164K - $262K *
Take ownership of software architecture and development to create scalable, user-centric applications. Lead comprehensive development initiatives while optimizing performance and mentoring engineers i...
Reposted 1 week ago
Staff Software Engineer, Containers
$205K - $231K *
Unlock potential by driving the technical direction and excellence of our stack. In this Staff Engineer role, you'll develop, mentor, and innovate within our Containers team, ensuring product quality...
Reposted 2 weeks ago
$185K - $225K *
Launch innovative full-stack solutions, owning features from backend to UI. Collaborate with a remote team to enhance agent workflows and ensure secure, reliable experiences in a regulated financial e...
3 weeks ago
Senior Software Engineer, AV Analysis Platform
$224K - $356K *
Pioneer the development of advanced evaluation tools for Autonomous Vehicles, enhancing workflows and system performance. Collaborate with cross-functional teams to deliver scalable solutions that imp...
1 week ago
Senior Software Engineer - Backend / Cloud Services
$110K - $135K *
Shape the future of IoT solutions by leading backend cloud services development. Drive technical design, mentor engineers, and ensure scalable architecture for AWS-based applications while enhancing u...
6 days ago
Software Engineer II - Cloud-Native Agent Harness (Mecatl)
$157K - $192K *
Develop and enhance a cloud-native agent harness, ensuring secure, reliable, and efficient operations. Collaborate with a dynamic team to deliver features, fix bugs, and innovate using AI throughout t...
Today
$230K - $368K *
Shape the future of high-scale SaaS solutions by leading architectural design, guiding teams, and driving impactful software strategies in a collaborative environment that values innovation and mentor...
Reposted 4 days ago
Software Engineer II, Cloud Applications
$110K - $130K *
Tackle the challenges of building scalable backend services in a cloud environment. Collaborate with cross-functional teams to enhance the Temporal Cloud experience, focusing on reliability, performan...
1 week ago
Staff Software Engineer, RestX
$220K - $240K *
Unlock the potential of restaurant operations by developing innovative, mission-critical software. Drive reliability and scalability across automated systems, enhancing guest experience and boosting r...
Reposted today
$190K - $267K *
Unlock potential by developing robust software solutions that enhance compliance and security programs. Collaborate across teams to automate processes, streamline workflows, and ensure timely risk man...
Today
$193K - $309K *
Lead the charge in delivering impactful GTM solutions by managing a skilled engineering team, overseeing technical operations, and fostering collaboration with stakeholders to drive innovation and qua...
4 days ago
Staff Software Engineer, Fullstack (Card Experiences)
$204K - $290K *
Lead the charge in creating seamless cardholder experiences by driving technical strategy, collaborating across teams, and fostering a culture of quality and ownership in a dynamic, AI-driven environm...
Yesterday
Senior/Staff Full Stack Software Engineer
$180K - $240K *
Build innovative software solutions for federal partners, focusing on full-stack development, user experience, and secure integrations. Collaborate with cross-functional teams to deliver impactful app...
4 days ago
Software Engineer 4/5 - Data and Feature Infrastructure, AI Platform
$466K - $500K+*
Elevate your career by building a cutting-edge ML data platform that enhances productivity for ML practitioners. Collaborate with experts to create innovative solutions for feature computation and sha...
Reposted 5 days ago
Engineering Lead, New Ventures
$230K - $368K *
Grow your career with a dynamic team that builds innovative solutions across full stack, focusing on customer needs and delivering impactful results in a fast-paced, startup-like environment...
Reposted 4 days ago
Staff Software Engineer, Android
$193K - $309K *
Lead the development of innovative drive-thru solutions, architecting scalable Android applications and backend integrations while mentoring engineers and driving engineering excellence across the org...
4 days ago
Staff Software Engineer, Security Factory: Static Analysis
$152K - $259K *
Transform security analysis by leading the development of a static analysis engine. Shape technical direction, mentor engineers, and drive initiatives that enhance code security and performance across...
3 weeks ago
Staff Software Engineer, Backend (Observability)
$230K - $290K *
Drive the architecture and strategy for a high-volume telemetry platform, mentoring a team while collaborating across functions to enhance observability practices and ensure system reliability at scal...
5 days ago
Senior Software Engineer, Compute Platform
$165K - $225K *
Champion the development of a GPU-accelerated compute platform, enhancing AI training and research capabilities. Collaborate with cross-functional teams to design orchestration systems that optimize r...
5 days ago
$160K - $200K *
Drive innovation by designing and developing scalable backend services, collaborating closely with engineering teams to enhance platform performance and reliability while mentoring junior developers a...
3 weeks ago
Senior Software Engineer - Integrations
$180K - $200K *
Deliver innovative backend solutions that enhance integrations and streamline security workflows. Collaborate with experts to build reliable services, ensuring seamless connectivity and improved inves...
5 days ago
Principal Software Engineer (Remote)
$176K - $220K *
Drive impactful platform engineering initiatives, leveraging deep expertise to architect scalable solutions and guide clients through complex technical landscapes while fostering collaboration and inn...
1 week ago
Senior Software Engineer, Virtualization and Linux Kernel
$224K - $431K *
Champion the advancement of open-source Linux kernel support for NVIDIA GPUs. Collaborate with global teams to develop virtualization features in Rust and C, driving technical proposals and enhancing...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.