Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$205K - $270K *

Drive your career forward by designing robust server architectures for AI solutions, ensuring high performance and scalability in fast-paced environments. Collaborate with top talent to architect syst...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Help us drive the future of automation by owning AI agents that onboard applications and ensure self-healing workflows. You'll enhance existing systems, prioritize security, and collaborate across tea...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$168K - $285K *

Lead the development of Test & Code Coverage capabilities, transforming complex challenges into actionable strategies. Collaborate with cross-functional teams to enhance software quality and streamlin...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Partner with us to deliver tailored solutions and in-depth demos, supporting a dynamic sales pipeline. Leverage your technical expertise to drive customer success and collaborate with teams to enhance...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Drive innovation by enhancing CI/CD systems for ML models, automating testing and deployment processes. Collaborate with teams to streamline workflows, reduce manual tasks, and ensure reliable model r...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$149K - $262K *

Unlock your potential by leading the design and deployment of innovative AI solutions. Collaborate with cross-functional teams to drive technical direction and ensure operational excellence in softwar...

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $160K *

Unlock potential by driving the evolution of AWS environments and CI/CD pipelines, enhancing observability and security, while collaborating with engineers to optimize platform reliability and perform...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $170K *

Transform backend services and APIs for high-volume interactions, ensuring reliability and performance. Drive platform evolution through hands-on design and implementation, collaborating with cross-fu...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $200K *

Join a team that's dedicated to enhancing user engagement through innovative front-end solutions. You'll leverage modern web technologies to build secure, high-performance financial applications that...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$69K - $107K *

Champion client success by leveraging technical expertise to enhance platform value, optimize workflows, and drive measurable outcomes. Collaborate with cross-functional teams to deliver innovative so...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Lead a dynamic team of software engineers to enhance data import systems, ensuring efficient document processing and integration. Drive technical direction, improve engineering practices, and foster a...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$184K - $356K *

Empower our team by designing and optimizing C++ software for ultra low-latency WebRTC streaming systems, driving innovation in real-time media applications and enhancing user experiences through adva...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$208K - $250K *

Shape the future of Grafana by leading frontend development squads, fostering collaboration and innovation to enhance user experiences. Drive AI integration and team growth while managing strategic pr...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Join a team that's dedicated to enhancing integration features across modern and legacy systems. You'll design APIs, deliver high-quality integrations, and collaborate with experienced engineers to dr...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $160K *

Empower our Managed Services tooling ecosystem by designing integrations and automations. You'll lead the configuration of Jira Service Management, optimize alerting, and ensure seamless connectivity...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Drive AI-native software development by architecting systems, guiding AI agents, and ensuring quality. Collaborate closely with users to transform business needs into reliable, efficient solutions whi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Empower clinical trial design by architecting robust data infrastructures that streamline insights extraction from diverse clinical documents, enhancing decision-making through advanced data pipelines...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform product operations by enhancing collaboration across teams and streamlining the launch processes. Utilize data-driven insights and AI to identify bottlenecks and drive efficiency, ensuring s...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$169K - $220K *

Join a team that's dedicated to transforming healthcare through innovative software solutions. Collaborate with engineers and healthcare professionals to build systems that enhance patient care and st...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's shaping the future of cybersecurity by designing and scaling automated test systems for a leading secrets management platform, ensuring quality and reliability in cloud-native servi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$86K - $165K *

Join a dynamic team to design and develop innovative flight management software for military applications, leveraging your expertise in software engineering within a collaborative AGILE environment fo...

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$135K - $160K *

Drive the development of scalable software solutions, enhancing computer vision and LLM systems. Collaborate with cross-functional teams to deliver impactful features while ensuring reliability and ef...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Elevate product innovation by leading cross-functional teams to develop AI tools and workflows. Drive project momentum through hands-on prototyping and clear communication, ensuring alignment between...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Lead the charge in shaping the technical landscape of digital accessibility. Drive innovation by designing scalable systems that enhance user experience while mentoring engineers and collaborating acr...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $160K *

Create impactful solutions as a Senior Product Engineer, owning projects from concept to delivery. Collaborate with a dynamic team, leveraging AI tools to enhance development while mentoring peers and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.