Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Senior Software Engineer, Backend (AI Agent)
$205K - $270K *
Drive your career forward by designing robust server architectures for AI solutions, ensuring high performance and scalability in fast-paced environments. Collaborate with top talent to architect syst...
Reposted yesterday
Staff AI Engineer, Agentic Automation
$150K - $180K *
Help us drive the future of automation by owning AI agents that onboard applications and ensure self-healing workflows. You'll enhance existing systems, prioritize security, and collaborate across tea...
1 week ago
Staff Product Manager, Agentic Test Intelligence
$168K - $285K *
Lead the development of Test & Code Coverage capabilities, transforming complex challenges into actionable strategies. Collaborate with cross-functional teams to enhance software quality and streamlin...
3 weeks ago
$80K - $95K *
Partner with us to deliver tailored solutions and in-depth demos, supporting a dynamic sales pipeline. Leverage your technical expertise to drive customer success and collaborate with teams to enhance...
Reposted 2 days ago
Senior Software Engineer, Machine Learning Infrastructure & Automation
$135K - $160K *
Drive innovation by enhancing CI/CD systems for ML models, automating testing and deployment processes. Collaborate with teams to streamline workflows, reduce manual tasks, and ensure reliable model r...
Reposted 6 days ago
Sr Consultant, Software Engineering - Forward Deployed Engineering
$149K - $262K *
Unlock your potential by leading the design and deployment of innovative AI solutions. Collaborate with cross-functional teams to drive technical direction and ensure operational excellence in softwar...
2 days ago
$140K - $160K *
Unlock potential by driving the evolution of AWS environments and CI/CD pipelines, enhancing observability and security, while collaborating with engineers to optimize platform reliability and perform...
1 week ago
Senior Software Engineer (Platform Core)
$130K - $170K *
Transform backend services and APIs for high-volume interactions, ensuring reliability and performance. Drive platform evolution through hands-on design and implementation, collaborating with cross-fu...
Reposted 4 weeks ago
Sr. Software Engineer - Front-End
$125K - $200K *
Join a team that's dedicated to enhancing user engagement through innovative front-end solutions. You'll leverage modern web technologies to build secure, high-performance financial applications that...
4 weeks ago
$69K - $107K *
Champion client success by leveraging technical expertise to enhance platform value, optimize workflows, and drive measurable outcomes. Collaborate with cross-functional teams to deliver innovative so...
Reposted yesterday
$120K - $145K *
Lead a dynamic team of software engineers to enhance data import systems, ensuring efficient document processing and integration. Drive technical direction, improve engineering practices, and foster a...
4 weeks ago
Senior Software Engineer - WebRTC Streaming
$184K - $356K *
Empower our team by designing and optimizing C++ software for ultra low-latency WebRTC streaming systems, driving innovation in real-time media applications and enhancing user experiences through adva...
1 week ago
Senior Engineering Manager, Grafana Frontend | USA | Remote
$208K - $250K *
Shape the future of Grafana by leading frontend development squads, fostering collaboration and innovation to enhance user experiences. Drive AI integration and team growth while managing strategic pr...
Reposted 3 weeks ago
Software Engineer (L2) - Platform Integrations
$100K - $120K *
Join a team that's dedicated to enhancing integration features across modern and legacy systems. You'll design APIs, deliver high-quality integrations, and collaborate with experienced engineers to dr...
3 weeks ago
Senior Tooling and Automation Engineer
$120K - $160K *
Empower our Managed Services tooling ecosystem by designing integrations and automations. You'll lead the configuration of Jira Service Management, optimize alerting, and ensure seamless connectivity...
1 week ago
Member of Technical Staff, Product & Engineering
$125K - $150K *
Drive AI-native software development by architecting systems, guiding AI agents, and ensuring quality. Collaborate closely with users to transform business needs into reliable, efficient solutions whi...
1 week ago
$120K - $145K *
Empower clinical trial design by architecting robust data infrastructures that streamline insights extraction from diverse clinical documents, enhancing decision-making through advanced data pipelines...
1 week ago
Senior Product Operations Manager
$110K - $130K *
Transform product operations by enhancing collaboration across teams and streamlining the launch processes. Utilize data-driven insights and AI to identify bottlenecks and drive efficiency, ensuring s...
Reposted 1 week ago
Senior Software Engineer, Interoperability
$169K - $220K *
Join a team that's dedicated to transforming healthcare through innovative software solutions. Collaborate with engineers and healthcare professionals to build systems that enhance patient care and st...
4 weeks ago
Software Development Test Engineer (SDET), KSM
$110K - $130K *
Join a team that's shaping the future of cybersecurity by designing and scaling automated test systems for a leading secrets management platform, ensuring quality and reliability in cloud-native servi...
1 week ago
Senior Software Engineer - AVI MIL FMS (Onsite)
$86K - $165K *
Join a dynamic team to design and develop innovative flight management software for military applications, leveraging your expertise in software engineering within a collaborative AGILE environment fo...
Yesterday
$135K - $160K *
Drive the development of scalable software solutions, enhancing computer vision and LLM systems. Collaborate with cross-functional teams to deliver impactful features while ensuring reliability and ef...
1 week ago
$120K - $150K *
Elevate product innovation by leading cross-functional teams to develop AI tools and workflows. Drive project momentum through hands-on prototyping and clear communication, ensuring alignment between...
1 month ago
$135K - $160K *
Lead the charge in shaping the technical landscape of digital accessibility. Drive innovation by designing scalable systems that enhance user experience while mentoring engineers and collaborating acr...
2 weeks ago
$130K - $160K *
Create impactful solutions as a Senior Product Engineer, owning projects from concept to delivery. Collaborate with a dynamic team, leveraging AI tools to enhance development while mentoring peers and...
1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.