Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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$130K - $160K *

Drive the customer experience for a leading finance app, ensuring intuitive, cohesive interactions across products. Collaborate with cross-functional teams to enhance usability, retention, and long-te...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$73K - $102K *

Serve as a key contributor in developing SAP HR ABAP solutions, collaborating with teams to design, implement, and enhance systems that meet client needs while ensuring compliance and data accuracy in...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Innovate with us to transform manual workflows into efficient AI-driven solutions. As a Staff Forward Deployed Engineer, you'll collaborate closely with teams to streamline processes, enhancing produc...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$75K - $120K *

Advance your career by implementing innovative SaaS solutions, configuring custom workflows, and driving system integration projects. Collaborate with a dynamic team to tackle complex challenges and d...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$190K - $200K *

Transform the future of work by driving AI-driven automation solutions. Engage with C-suite and technical stakeholders to showcase tailored integrations, enhance productivity, and build strategic rela...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$117K - $129K *

Lead the charge in optimizing operational performance for solar energy projects. Collaborate with engineers to analyze performance data, develop solutions, and ensure project success, while fostering...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$212K - $265K *

Drive transformative software engineering across EPM products, lead modernization, build innovative SaaS capabilities, and enhance operational excellence in a high-impact role overseeing global teams...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$139K - $174K *

Engineer impactful electrical systems by leading projects, mentoring teams, and ensuring compliance with industry standards. Collaborate to foster innovation and quality in complex building designs, d...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$240K - $330K *

Champion the development of onboard software for autonomous vehicles, leading cross-functional teams to ensure a robust software foundation. Drive strategic vision, quality, and operational excellence...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Transportation

$95K - $115K *

Transform digital experiences for military families by developing secure, responsive websites and applications. Collaborate with cross-functional teams to enhance user engagement and accessibility whi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$72K - $90K *

Lead data-driven insights to enhance business performance, collaborating across teams to support strategic initiatives. Utilize technical skills in SQL, Python, and data visualization to drive impactf...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $500K+*

Deliver innovative mechanical designs for AI compute systems, enhancing data center capabilities. Collaborate on all facets of product development, ensuring high-quality assembly and performance throu...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $120K *

Elevate software quality assurance by testing GIS applications and validating complex datasets. Collaborate with developers and GIS specialists to ensure accuracy and reliability in geospatial data fo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $130K *

Grow your career with a dynamic role that involves conducting in-depth research across various topics, delivering actionable insights, and collaborating with a high-performing team to tackle complex q...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $160K *

Champion cloud and application security by enhancing AWS practices, collaborating with cross-functional teams, and driving continuous improvement to ensure secure and compliant environments...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$216K - $318K *

Drive innovation as you lead engineering teams to build and scale Life360's critical platforms. Ensure reliability and security while fostering a culture of accountability and technical excellence for...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$96K - $124K *

Join a team that's committed to resolving complex technical issues for customers. You'll drive personalized support, streamline problem resolution, and improve service processes, all in a fast-paced...

RemoteRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$140K - $180K *

Lead the charge in driving innovative solutions as a Principal Solutions Engineer, collaborating with sales teams to deliver tailored technical proposals and enhance customer success through expert gu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Lead the charge in architectural innovation and technical strategy across systems. Shape long-term solutions, drive frontend performance, and foster cross-functional collaboration to enhance user expe...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$120K - $145K *

Drive the development of the PSA Liquidity Platform, enhancing buyer and seller experiences while managing cross-functional teams to deliver high-impact solutions that bolster marketplace efficiency a...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$239K - $298K *

Champion a high-performing mobile engineering team to innovate financial tools, fostering collaboration and mentorship while driving product development across iOS and Android platforms for a dynamic...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $190K *

Transform the AI landscape by architecting and building the Vector Store GenAI Platform, enhancing document intelligence and retrieval for clinical applications. Collaborate with cross-functional team...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$184K - $194K *

Drive your career as a Senior Product Manager, shaping innovative retailer experiences and analytics solutions. Lead cross-functional teams to deliver impactful products that empower retailers to thri...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Join a dynamic team as you lead and enhance partner programs, ensuring effective onboarding, enablement, and communication with technology partners to drive mutual success and streamline processes for...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$180K - $200K *

Join us to investigate and resolve platform issues, ensuring quality across campaigns. Collaborate with cross-functional teams to enhance processes, automate checks, and maintain high standards in a f...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.