Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$90K - $110K *

Join a team that's dedicated to enhancing cybersecurity measures while independently managing security operations and engineering tasks across various platforms and environments to support business co...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$245K - $344K *

Grow your impact by shaping the advertising experience at the intersection of design and engineering. Lead UX engineering strategy across teams, create high-quality prototypes, and drive product direc...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Media

$100K - $120K *

Join a team that's redefining financial strategies. As a Senior FP&A Analyst, you will lead R&D budgeting, forecasting, and variance analysis, impacting vital business decisions while collaborating wi...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $200K *

Unlock potential by bridging U.S. and Japan engineering teams. This strategic role involves aligning product direction, enhancing platform use, and prioritizing high-impact solutions in a fast-paced...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $140K *

Unlock your potential as a senior technical contributor, leading infrastructure design and implementation. Drive strategic decisions, mentor junior engineers, and enhance system performance in a dynam...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $120K *

Unlock your potential as a Project Manager, leading complex, cross-functional projects. Oversee multiple initiatives, ensuring timely delivery and budget adherence while mentoring team members and enh...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$135K - $160K *

Join us to lead the deployment of AI-driven ERP solutions, enhancing SAP S/4HANA capabilities. Collaborate with cross-functional teams to ensure scalable, reliable, and secure automation across critic...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Advance your career by owning corporate FP&A, driving financial insights, and partnering with leaders across functions to enhance strategic planning and reporting in a dynamic growth-stage environment...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $160K *

Join a team of expert engineers to innovate a Kubernetes resource management platform, enhancing DevOps productivity and addressing complex engineering problems in a dynamic environment...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Innovate scalable runtimes to support diverse AI hardware accelerators while driving ML optimization with Triton. Collaborate on groundbreaking technologies to establish foundational frameworks in AI...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Accelerate progress at the forefront of power connector innovation, leading product development initiatives while driving cross-functional collaboration and mentoring engineering talent to deliver hig...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $160K *

Transform ML research into production-ready models, enhancing workflows and systems. Collaborate with scientists to develop efficient pipelines for deploying models rapidly and reliably, optimizing pe...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$83K - $125K *

Drive the operational health of mission-critical Appian environments, ensuring reliability and performance. Collaborate with cross-functional teams to manage configurations, deployments, and incident...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$168K - $285K *

Shape the future of competitive strategy in AI and agentic software development. Drive market differentiation, collaborate with cross-functional teams, and establish a compelling narrative that enhanc...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $210K *

Drive innovation by designing and building full-stack features for a dynamic web application, tackling complex challenges in real-time collaboration and high-performance rendering while mentoring engi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Lead the charge in developing and supporting PLC control systems in critical infrastructure. Collaborate with experts to ensure reliable automation across diverse facility systems while meeting client...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Drive the product vision and strategy, owning the lifecycle from discovery to launch, focusing on scalability and performance in a cloud-based platform. Collaborate with stakeholders to ensure innovat...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$118K - $219K *

Transform the future of cloud infrastructure by leading a dynamic SRE team, driving automation, and enhancing operational excellence across scalable platforms while fostering collaboration and continu...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Optimize program delivery by leading complex projects from proposal to execution. Drive cross-functional collaboration, manage budgets, and ensure customer commitments are met while mentoring junior p...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $130K *

Join a team that's transforming businesses through data-driven strategies and hands-on execution. Drive client engagement in banking and wealth management, collaborating cross-functionally to deliver...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Lead the charge in advanced mechanical design for controllable propulsion systems. Manage a talented engineering team, tackle complex design challenges, and ensure alignment of mission goals with engi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$250K - $300K *

Join a team that's redefining enterprise solutions! Leverage your expertise in networking and security to drive technical sales, support customer adoption, and influence product development while coll...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $154K *

Elevate your career by installing and programming advanced electronic security systems. Collaborate with a dynamic team to ensure the integrity of communication and power systems while adhering to ind...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Join a team that's dedicated to delivering high-quality software solutions using C# and .NET technologies. Collaborate in an Agile environment to drive innovation and optimize performance while suppor...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $160K *

Drive the customer experience for a leading finance app, ensuring intuitive, cohesive interactions across products. Collaborate with cross-functional teams to enhance usability, retention, and long-te...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.