Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Technical IBM Mainframe Applications/Systems Analyst
$75K - $105K *
Optimize mainframe systems as a key analyst, ensuring stability and performance of IBM z/OS environments. Collaborate with teams to troubleshoot issues and maintain critical applications, while enhanc...
Yesterday
$120K - $145K *
Join a team that's redefining product management by leading cross-product initiatives and shared services. Collaborate with diverse teams to drive innovation, enhance platform capabilities, and delive...
Today
$175K - $240K *
Transform customer engagement by deploying innovative AI solutions, guiding installations, and crafting tailored integrations while enhancing product tools based on real-world usage and feedback for s...
Reposted 4 weeks ago
$85K - $165K *
Champion safety in innovative nuclear fuel recycling by evaluating hazards, developing safety documents, and ensuring compliance with regulations. Collaborate in a dynamic team to enhance safety measu...
2 weeks ago
Senior Site Reliability Engineer
$130K - $155K *
Transform our platform by enhancing performance and reliability as a Senior Site Reliability Engineer. Collaborate with teams to optimize Ruby on Rails applications, leverage AI for operational effici...
2 weeks ago
$77K - $117K *
Drive day-to-day operations of Azure and Microsoft 365 services, ensuring optimal performance, incident management, and compliance with service levels while supporting service transitions and maintena...
3 weeks ago
$117K - $129K *
Shape the future of eCommerce by developing dynamic, high-performance web applications. Collaborate with a diverse team to create responsive and robust user interfaces while leveraging the latest tech...
3 weeks ago
$163K - $245K *
Support the sales team by providing technical expertise and solutions for F5 products. Engage with customers to understand their needs, drive sales processes, and deliver world-class service while ach...
5 days ago
$133K - $200K *
Inspire technical excellence by supporting sales teams with F5 solutions, driving customer engagement, and delivering tailored presentations. Collaborate with internal resources to achieve sales targe...
5 days ago
Security Engineer, Vulnerability Management & Security Operations
$120K - $145K *
Lead our vulnerability management and security operations program, shaping it from the ground up. Collaborate with a small Trust team to enhance our security posture and ensure compliance while automa...
Today
$125K - $150K *
Provide advanced Hogan ILP development support through coding, design, and testing for our client's system. Work collaboratively on technical solutions, focusing on enhancing application performance a...
Reposted 3 weeks ago
$120K - $145K *
Grow your career with a dynamic role focused on developing responsive applications and secure APIs. Collaborate across teams to implement integrations and optimize performance while leveraging modern...
Yesterday
Senior SCADA Engineer - Graphics
$100K - $120K *
Solve complex challenges as a Senior SCADA Engineer, designing intuitive automation graphics for advanced control systems. Collaborate with diverse teams to enhance project outcomes and mentor junior...
Reposted 4 weeks ago
$125K - $145K *
Innovate solutions as a Senior ServiceNow Developer by delivering complex platform engineering support, enhancing integrations, and improving automation. Collaborate on enterprise-level applications w...
1 month ago
$115K - $140K *
Oversee large-scale industrial automation projects from concept to commissioning. Lead cross-functional teams, ensuring timely delivery, budget adherence, and quality standards while mentoring future...
3 days ago
Staff Software Engineer - Provider Growth & Activation (Remote)
$135K - $160K *
Champion innovative solutions as a Staff Software Engineer, driving impactful software development to enhance provider experiences and streamline care delivery. Collaborate across teams to shape techn...
2 weeks ago
$110K - $138K *
Drive cybersecurity excellence by assessing and securing technology environments during mergers and acquisitions, ensuring compliance and integration of critical systems across diverse platforms...
1 week ago
$110K - $130K *
Drive the strategy and execution of an AI framework for state government, ensuring responsible AI use and fostering innovation. Collaborate with stakeholders to implement effective AI initiatives that...
4 weeks ago
Senior Cyber Security Engineer
$130K - $190K *
Lead and innovate in cybersecurity by enhancing security delivery through automation and AI. Collaborate across teams to identify gaps, improve compliance, and strengthen processes, ensuring consisten...
3 weeks ago
GIS Software Quality Assurance Engineer
$95K - $120K *
Champion quality assurance in GIS software by developing test plans, validating data, and ensuring reliability for Army geospatial applications. Collaborate with experts to enhance automated testing p...
1 week ago
$66K - $106K *
Contribute to the modernization of America's airspace by executing software installations and updates for the FAA's Terminal Flight Data Manager program, ensuring operational readiness and compliance...
3 days ago
$133K - $180K *
Help us transform healthcare solutions as you engage with clients, translate complex AI capabilities into actionable plans, and drive successful implementations within a collaborative environment focu...
3 weeks ago
Mobile Implementation Specialist
$96K - $148K *
Unlock the potential of government partnerships by managing client projects across the US. Support project design, training, and implementation, ensuring optimal client experiences and delivering succ...
Reposted 6 days ago
Staff Application Security Engineer
$225K - $281K *
Shape the future of application security by leading strategy and initiatives across teams. Drive secure design and standards, mentor engineers, and tackle complex security challenges in a collaborativ...
1 week ago
Principal Enterprise Architect
$177K - $290K *
Transform enterprise architecture by defining and implementing core frameworks, driving AI integration, and building consensus across teams. Lead the development of standards and strategies to support...
3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.