Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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$110K - $130K *

Transform your career by leading Microsoft Cloud security projects, deploying SIEM and XDR solutions, and enhancing customer environments. Collaborate with a dynamic team to drive innovation in Manage...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by transforming complex data into actionable insights. Collaborate with leaders across functions to create KPIs, analyze business performance, and foster a data-driven culture through...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$111K - $150K *

Elevate your career by leading the design and integration of advanced electrical control systems. Collaborate with engineering teams to enhance efficiency and mentor junior members while ensuring proj...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $205K *

Lead the charge in delivering client-focused mainframe solutions. Oversee diverse projects, manage teams, and leverage strategic insights to enhance hardware and software lifecycle management while fo...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$85K - $102K *

Lead the charge in delivering innovative structural designs for diverse projects, ensuring seamless collaboration across disciplines while mentoring junior engineers and overseeing construction admini...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$111K - $180K *

Unlock potential by designing AI-powered solutions for complex reporting challenges. Collaborate with customers and cross-functional teams to deliver innovative outcomes in regulated environments whil...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $122K *

Join a team that's redefining DevOps by building and maintaining CI/CD pipelines, automating workflows, and enhancing service delivery in AWS. Collaborate with cross-functional teams to ensure reliabl...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $160K *

Accelerate progress at securing cloud environments by designing robust guardrails and automation. Collaborate with engineering teams to embed security into CI/CD pipelines and ensure compliance across...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$164K - $262K *

Advance your career by designing and operating AI systems for mortgage Fulfillment. Lead architecture, build evaluation frameworks, and ensure reliability while collaborating with cross-functional tea...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Transform customer experiences by leading solution discovery and deployment for enterprise software. Collaborate with Fortune 500 clients to operationalize innovative solutions, ensuring quality and e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Elevate cybersecurity by designing and implementing robust security protocols, ensuring compliance across cloud infrastructure while managing IAM, PKI, and secrets management to protect fintech worklo...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $500K+*

Accelerate progress at the forefront of silicon verification. Own and enhance methodologies, manage test execution, and drive crucial reviews to ensure successful design transitions from concept to pr...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$186K - $218K *

Join a team that's redefining mobile experiences by architecting automated QA processes for iOS and Android. Leverage your expertise to ensure exceptional quality in a fast-paced environment, collabor...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $148K *

Join a dynamic team providing expert software support for mainframe IMS systems. Engage in customer service, problem resolution, and migration services while adhering to best practices and ensuring ti...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Lead robust cloud infrastructure solutions in AWS and AWS GovCloud, ensuring CI/CD and security compliance across environments. Collaborate with teams to optimize deployment and operational processes...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$207K - $218K *

Join a team that's shaping the future of financial systems by owning backend services for secure fund movement across fiat and crypto. Drive technical direction, mentor engineers, and enhance system r...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$220K - $270K *

Join a team that's pushing the boundaries of machine learning in autonomous vehicles. Enhance driving capabilities, lead innovative teams, and drive commercial-scale solutions with cutting-edge techno...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$160K - $500K+*

Engage in cutting-edge verification methodologies to drive scalable solutions across blocks and systems, ensuring robust validation at the chip level. Champion verification execution, planning, and cl...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$194K - $272K *

Drive modernization efforts across complex infrastructure programs, collaborating with engineering teams to ensure successful execution and alignment with long-term strategies. Leverage technical expe...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$165K *

Champion innovative solutions as a Platform Site Reliability Engineer, enhancing infrastructure, optimizing deployment pipelines, and ensuring system reliability, scalability, and security in collabor...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Empower your career by leveraging your cybersecurity expertise to drive software modernization initiatives. Contribute to operational objectives while ensuring compliance within a collaborative Agile...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Drive the design and optimization of scalable, reliable infrastructure for AI-driven cybersecurity. Collaborate across teams to enhance performance and automate processes, ensuring efficient operation...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$149K - $201K *

Join a team that's transforming data into impactful AI solutions. As an AI Engineer/Architect, you'll lead innovative projects, collaborate with stakeholders, and drive automation in mission-critical...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$171K - $235K *

Develop and lead education-first technical sessions within enterprise accounts, fostering collaboration with engineers to build champions, enhance user knowledge, and uncover opportunities for expansi...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$170K - $230K *

Engineer the future of edge-AI by converting customer evaluations into design wins. Collaborate with engineering teams to optimize workloads on our innovative Chimera architecture, shaping the next ge...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.