Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Senior AWS Python Developer / Ops Engineer
$130K - $155K *
Drive the design and development of resilient AWS serverless services, collaborating with senior engineers to enhance platform capabilities while ensuring operational excellence and high-quality autom...
3 weeks ago
$125K - $150K *
Join a team that's shaping the future of cloud infrastructure by managing a vast AWS estate. Drive automation, maintain platform health, and deliver new features while ensuring compliance in a regulat...
1 week ago
$126K - $200K *
Lead technical solutions architecture for HPE storage platforms, guiding partners and sales teams in developing resilient infrastructure solutions. Drive engagement, enablement, and strategic initiati...
Yesterday
Digital Workplace Deployment Engineer
$100K - $120K *
Lead the charge in transforming legacy messaging solutions to modern Google technologies. Utilize your expertise in Google Workspace migrations and project management to drive successful deployments a...
3 weeks ago
Sr. Software Engineer/Tech Lead, Data & AI Engineering
$150K - $188K *
Elevate your career by designing and building innovative data solutions that empower genomic research and analysis. Collaborate with scientists in a fast-paced R&D environment to support impactful dis...
Reposted 3 weeks ago
Staff Product Manager - Agent & Systems Observability
$135K - $160K *
Transform observability in AI with strategic vision, driving technical progress across systems and agent telemetry, while enhancing developer experiences and guiding product direction at the intersect...
Reposted 3 weeks ago
Principal Technical Consultant - Forward Deployed Engineer, AI Security
$200K - $230K *
Lead a team that operationalizes advanced AI security solutions for enterprises, ensuring integration and compliance across environments. Collaborate with stakeholders to translate requirements into e...
3 weeks ago
$135K - $160K *
Join a team that's redefining data architecture by leading innovative modeling and integration initiatives. Collaborate with AI Engineers to create scalable datasets and optimize performance in a mult...
1 week ago
Senior Software Engineer (Institutional, Financing)
$207K - $218K *
Unlock potential by designing and scaling backend systems for high-value financing operations, ensuring safety and reliability while driving revenue and trading activity in a dynamic financial environ...
2 weeks ago
$130K - $160K *
Lead engineering efforts by writing production code and mentoring a team. Drive modernization initiatives through Java microservices while managing performance and growth of engineers. Collaborate wit...
Today
Principal Data Platform Engineer
$160K - $185K *
Shape the future of data engineering by leading the architecture and evolution of a robust enterprise data platform, ensuring reliability and integration across analytics, reporting, and AI capabiliti...
2 weeks ago
$100K - $120K *
Lead the charge in optimizing project management processes for a VHA client team. Utilize your expertise to enhance strategic planning, decision-making, and execution while collaborating with senior s...
2 weeks ago
Staff Software Engineer, Care Experience
$193K - $309K *
Lead the charge in transforming care agent tools, enhancing system reliability and performance. Collaborate with cross-functional teams to design and implement solutions that streamline support proces...
1 week ago
$100K - $120K *
Analyze customer needs and advance technical solutions in cybersecurity, collaborating with sales and product teams to deliver impactful presentations and proposals while ensuring seamless product int...
Reposted 2 weeks ago
$105K - $177K *
Elevate your career by mastering Oracle software engineering in a dynamic, remote environment. Collaborate with a skilled team to enhance database performance and support critical applications while d...
Reposted 3 days ago
$117K - $157K *
Join a team that's transforming enterprise AI solutions through innovative design and deployment. Leverage your expertise to build secure, scalable AI platforms that enhance business processes and dri...
4 days ago
$110K - $130K *
Advance software development by leading projects, mentoring engineers, and architecting solutions. Collaborate across teams to enhance performance and functionality while staying updated on technology...
1 week ago
Senior Director Software Engineering
$286K - $326K *
Champion engineering excellence by leading high-performing teams to innovate scalable, customer-centric solutions. Drive technical strategy and architecture while fostering a culture of continuous lea...
1 week ago
$103K - $138K *
Unlock potential by designing and automating secure, scalable AWS cloud platforms. Collaborate with cross-functional teams to enhance infrastructure reliability and streamline software delivery throug...
1 week ago
$90K - $153K *
Engineer and deploy secure AI-driven applications and automation solutions, enhancing operational efficiency and collaboration across teams. Leverage Generative AI and cloud technologies to solve comp...
1 week ago
$110K - $130K *
Engage in advanced engineering of the ServiceNow platform, driving stability and scalability. Collaborate with teams to implement upgrades and integrations, utilizing modern practices to enhance servi...
Reposted 3 weeks ago
$135K - $160K *
Elevate your career by building transformative backend services and distributed systems that empower enterprises to monitor AI effectively. Drive projects from vague concepts to deployed products whil...
3 weeks ago
Senior Structural Engineer 1 - Grid
$84K - $129K *
Join a team that's dedicated to innovative structural engineering solutions. Leverage your expertise in materials and design to tackle complex challenges in power transmission upgrades, ensuring clien...
3 weeks ago
Senior Software Engineer, Stablecoins
$186K - $218K *
Join our team to advance the development of innovative stablecoin solutions, blending backend engineering with smart contract expertise. Be integral in shaping scalable services and driving architectu...
Reposted 3 weeks ago
Engineering Manager, Proactive Security - Pods
$193K - $285K *
Redefine the future of security at scale by leading innovative product engineering efforts. Drive collaboration, technical vision, and proactive controls to ensure a secure and resilient delivery ecos...
Reposted 2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.