Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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$130K - $160K *

Drive the development of autonomous AI systems that enhance decision-making across platforms. Shape AI architecture, integrate tools, and lead the creation of impactful AI solutions from concept to pr...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$172K - $229K *

Lead the charge in designing and validating complex systems for autonomous vehicle performance, ensuring seamless integration between software, operations, and customer interfaces to support the launc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$114K - $191K *

Lead the charge in shaping high-impact SaaS solutions by driving technical strategy and empowering a high-performing engineering team. Collaborate across disciplines to foster innovation in a fast-pac...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Transform large-scale project design by leading ILA/A&E engineering initiatives. Own technical solutions from site evaluation to construction support, fostering ADB's growth through effective collabor...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$131K - $205K *

Shape the future of electric power projects by providing expert development support, technical evaluations, and engineering design reviews. Collaborate with clients to optimize project outcomes while...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Technical Services

$105K - $202K *

Create innovative AI-powered healthcare products by transforming complex workflows into intuitive applications. Collaborate with cross-functional teams to deliver impactful user experiences and own fe...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$199K - $270K *

Shape the future of software development by enhancing tooling, CI/CD, and operational workflows, ensuring teams can seamlessly transition code changes into production with improved speed, quality, and...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$203K - $345K *

Champion the vision for Agentic Software Delivery, spearheading strategic innovation across CI, CD, and observability to enhance software delivery automation and customer experience while driving reve...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$155K - $210K *

Lead complex programs and strategic client engagements, driving technology transformation and sustainable business value. Act as a trusted adviser to C-level stakeholders, shaping program vision and e...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$145K - $180K *

Shape the future of our threat detection products! Lead a small, dynamic team, take ownership of complex architectures, and collaborate with product management to deliver critical customer-facing solu...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Join a dynamic team to enhance mobile experiences by developing and maintaining iOS features. Collaborate across disciplines to create intuitive financial workflows while ensuring security, performanc...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$164K - $229K *

Unlock your potential as a mid-level frontend engineer, leading projects that enhance advertiser experiences. Collaborate with diverse teams, build intuitive tools, and drive performance while making...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$104K - $166K *

Accelerate automation initiatives by developing end-to-end solutions using Ansible, Python, and RESTful APIs. Collaborate with cross-functional teams to enhance operational efficiency and ensure compl...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$122K - $176K *

Engage in meaningful technical challenges, collaborating with experienced engineers to develop core components and innovative tools, while automating infrastructure to enhance system performance and s...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$160K - $180K *

Join a dynamic team driving innovative cloud storage solutions. Lead engineering efforts to design and maintain high-performance storage services globally, ensuring reliability and scalability for div...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$177K - $364K *

Unlock your potential by driving automated traffic management and shaping rate limiting platforms, while leading collaboration across vendors and mentoring engineers to enhance performance in Edge sys...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$162K - $219K *

Champion the development of system integrity and speed across engineering teams, ensuring gameplay features are tested thoroughly and efficiently. Build the testing infrastructure that enhances qualit...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$139K - $235K *

Champion the backend usage billing pipeline, driving product direction and ensuring seamless integration for credit-based offerings while enhancing scalability and reliability across platforms...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$145K - $200K *

Reimagine the user experience by building scalable, data-driven solutions in a collaborative environment. Leverage your skills in full-stack development to enhance our experimentation platform while t...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $165K *

Lead the charge in designing and scaling foundational APIs and backend services, optimizing cloud data stores, and ensuring high-availability for a robust platform. Elevate technical standards while s...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Drive operational excellence by enhancing reliability and performance of a SaaS platform. Collaborate with development teams to implement automation, incident management, and observability practices...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Empower our team by developing and maintaining web applications that enhance user experience and support critical health programs. Collaborate with stakeholders to ensure seamless integration and robu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $225K *

Elevate your career by leading a dynamic Security Engineering team. Drive technical direction, own security architecture, and collaborate closely with operations to build robust security platforms and...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$209K - $250K *

Engineer scalable backend services and APIs to enhance our global marketplace. Collaborate with cross-functional teams, utilizing modern technologies like Go, Python, and Redis to deliver high-perform...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Engage in transformative DevOps practices by implementing AWS technologies and tooling. Collaborate with product teams to enhance cloud infrastructure, security, and CI/CD pipelines, contributing to a...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.