Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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$150K - $180K *

Shape the future of security by leading cross-functional initiatives to enhance incident detection and response capabilities. Collaborate with diverse teams to identify risks, develop automation, and...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$135K - $160K *

Join a team that's shaping the future of AI integration in product development. Lead the creation of an AI-native PDLC framework, enhancing workflows through innovative AI solutions while collaboratin...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$105K - $155K *

Shape project success by leading engineering efforts, managing budgets, and ensuring compliance with industry standards. Collaborate with teams to deliver high-quality results on time and within scope...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$162K - $290K *

Shape the technical direction of a geospatial platform, building scalable systems and APIs that enhance location-aware experiences across products, while collaborating with teams to drive innovation a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$94K - $179K *

Join a team that's dedicated to designing and developing high-quality software solutions. Lead agile projects, mentor junior engineers, and ensure robust application systems that meet user needs and i...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$208K - $234K *

Drive the growth of Honeycomb Private Cloud by leading a senior engineering team, enhancing customer relationships, and ensuring operational excellence across multiple engineering domains. Collaborate...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $160K *

Lead the end-to-end customer onboarding process, managing cross-functional teams to ensure timely delivery and value realization. Collaborate with customers to provide expert guidance and drive succes...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Take ownership of complex technical issues, driving resolution and enhancing customer experience through deep problem-solving and collaboration with cross-functional teams...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Elevate user experiences by creating impactful UI for a mobile app and browser extension. Collaborate closely with design and marketing to deliver polished, intuitive interfaces that enhance shopper i...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$159K - $215K *

Take ownership of Windows endpoint reliability and lifecycle management. Enhance provisioning, patching, and automation while collaborating with cross-functional teams to drive improvements and mentor...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Join our team to validate and enhance data migration processes through comprehensive testing, ensuring quality and performance in a dynamic Agile environment. Your expertise will drive successful syst...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Champion innovation as a Senior Full Stack Developer, crafting cutting-edge AI solutions to redefine recruitment processes, while leading a dynamic team in a fast-paced environment...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Join a team that's redefining software engineering by integrating AI tools to accelerate the development process. Transform requirements into reliable solutions while ensuring quality, security, and m...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $165K *

Unlock potential by joining a dynamic engineering team focused on resolving issues, enhancing systems, and automating processes to improve member experiences and operational efficiency...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Lead the charge in building a secure, self-service developer sandbox on Azure, delivering non-persistent desktops and managing the entire stack from landing zone to golden image while ensuring complia...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$131K - $164K *

Join a team that's redefining restaurant technology by building robust mobile applications. As a Senior Software Engineer II, you'll lead feature delivery, optimize performance, and collaborate across...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$130K - $160K *

Champion the migration to a modern Databricks lakehouse, designing robust data pipelines and ensuring data quality. Collaborate with teams to enhance analytics capabilities and set technical standards...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$124K - $210K *

Drive customer success by leading a team of engineers to enhance GitLab adoption, develop scalable enablement programs, and collaborate with cross-functional teams to achieve measurable business outco...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$118K - $216K *

Innovate and drive growth by designing and executing high-velocity monetization experiments. Collaborate with cross-functional teams to transform hypotheses into impactful Android features, leveraging...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Join us to transform AI prototypes into resilient production systems using Microsoft Azure. Collaborate directly with teams to build and refine agentic systems, ensuring quality and security while dri...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Empower your career by leading and scaling a multidisciplinary engineering team in full-stack and data engineering. Drive impact through collaboration and technical excellence, ensuring quality and in...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $130K *

Optimize quality assurance processes by designing and maintaining automation frameworks that enhance software reliability and delivery speed. Collaborate with cross-functional teams to ensure complian...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$152K - $179K *

Drive the development of distributed systems for real-time blockchain data ingestion and indexing, owning services from design to production while enhancing performance and reliability across the plat...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $170K *

Accelerate progress at the forefront of real-time media ingestion, designing and operating distributed services that enhance communication data processing for analytics and security. Lead projects and...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Join a team that's dedicated to providing exceptional post-sales technical support for federal clients. You'll troubleshoot complex systems, collaborate with engineering teams, and ensure seamless ope...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.