Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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$169K - $220K *

Join a team that's dedicated to transforming healthcare through innovative software solutions. Collaborate with engineers and healthcare professionals to build systems that enhance patient care and st...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Optimize energy solutions by leading technical projects, conducting site surveys, and collaborating with teams to deliver innovative, cost-effective strategies that enhance facility performance and su...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $120K *

Drive innovation in digital experiences by building and optimizing high-performing web applications. Collaborate with creative teams to enhance customer engagement across platforms while managing the...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $180K *

Transform user experiences by developing innovative web applications with cutting-edge technologies. Collaborate with cross-functional teams to create exceptional battery analytics software for leadin...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$120K - $145K *

Transform energy solutions by leveraging AI to optimize operations and products. Collaborate with teams to define success metrics, design LLM-powered features, and enhance customer-facing AI functiona...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$150K - $300K *

Transform enterprise operations by developing AI solutions tailored to customer needs. Engage directly with clients, manage the full technical lifecycle, and drive measurable improvements in AI perfor...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $155K *

Join a team that's dedicated to building innovative marketplace solutions. As a Senior Software Engineer, you'll collaborate with cross-functional teams to deliver high-quality software, enhancing fle...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$103K - $181K *

Join a dynamic team to shape innovative frontend solutions for critical defense applications. Leverage your expertise in React and TypeScript to create intuitive user interfaces that enhance decision...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$220K - $260K *

Innovate secure identity management practices by defining and developing authentication, authorization, and delegation systems for agentic AI applications. This role requires a strategic leader with a...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $220K *

Deliver innovative data pipelines for legal records, transforming unstructured data into actionable insights while supporting advanced AI workflows and data quality improvements for robust legal resea...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$123K - $254K *

Architect innovative full-stack solutions that enhance user experiences, collaborating with cross-functional teams to drive product development from ideation to release, while ensuring high-quality co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$130K - $180K *

Build a robust data foundation to elevate Market Intelligence. Drive automation and streamline data workflows, enriching insights for research and publishing, while ensuring data integrity and accessi...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $300K *

Join a team that's embedding security into every software development phase, enhancing product safety and reliability while directly influencing our technology offerings. You'll collaborate with engin...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$120K - $145K *

Join us to enhance the security posture of our production platform. As an Infrastructure Security Engineer, you'll drive remediation efforts, build security frameworks, and collaborate with teams to p...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$198K - $297K *

Join us to lead the design and evolution of a cutting-edge Real-Time Analytics Platform, driving high-throughput, low-latency data solutions. Collaborate with cross-functional teams to enhance scalabi...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Elevate talent acquisition at a dynamic tech company by leading comprehensive recruiting strategies, collaborating with cross-functional teams, and enhancing candidate experiences to drive sustainable...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $500K+*

Help us define, design, and validate power architecture for AI data centers, driving innovation in power efficiency and system performance. Collaborate across teams to bring cutting-edge solutions fro...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$166K - $230K *

Empower your career as a Senior Infrastructure Engineer focusing on enhancing Lakehouse infrastructure, security, and cost efficiency while collaborating with cross-functional teams to optimize data p...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Transform data solutions by architecting enterprise-grade pipelines, leading a high-performing team, and embedding best practices to create scalable, robust data environments for analysis and insights...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$195K - $270K *

Lead a high-performing team to optimize data lifecycle processes for ML models, driving improvements in data evaluation velocity and production readiness by integrating robust infrastructures and fost...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $185K *

Elevate your career by managing a dynamic data engineering team, shaping scalable data pipelines, and driving innovative data solutions to enhance enterprise data strategies and execution efficiency a...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate your career by developing innovative cloud-native applications that drive next-gen conversational AI solutions. Collaborate with cross-functional teams to create scalable backend services and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$115K - $135K *

Unlock potential by building and maintaining scalable data pipelines for GenAI solutions. Collaborate with cross-functional teams to ensure data compliance, governance, and access control, enabling se...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Finance & Insurance

$200K - $250K *

Join us to architect and lead the development of scalable fintech solutions. As a technical leader, you'll drive innovation, mentor teams, and ensure architectural integrity while shaping the future o...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock your potential by leading data initiatives and shaping insights through collaboration with stakeholders. Drive innovative BI solutions, ensuring clarity and reliability in analysis, while guidi...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.