Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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$110K - $130K *

Partner with us to design and implement cloud-native data solutions, ensuring secure and reliable data exchange across platforms. Collaborate with teams to enhance data accessibility and support advan...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in engineering management, facilitating industry standards and guidance. Collaborate with cross-functional teams to develop technical reports and oversee project execution while drivin...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $180K *

Unlock potential by leading application security initiatives, enhancing product security, and driving secure development practices. Collaborate with engineering teams to establish standards, manage vu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$96K - $130K *

Join a dynamic team to shape innovative fundraising tools that empower progressive campaigns and nonprofits. Leverage modern technologies to enhance election readiness and compliance, while mentoring...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $120K *

Elevate your career by managing IT operations, vendor relationships, and internal projects. Lead endpoint management and ensure service quality while driving technology transitions and compliance init...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $100K *

Optimize software solutions by developing, integrating, and supporting applications within an ICAM workstream, ensuring high quality and security standards. Collaborate in CI/CD environments and provi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$125K - $150K *

Join a dynamic team to design and implement innovative data solutions, leveraging Azure Databricks and advanced ETL/ELT processes. Empower data-driven insights and mentor fellow engineers while enhanc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$107K - $150K *

Drive the design and delivery of advanced AI solutions, mentoring engineers and ensuring client satisfaction. Collaborate with stakeholders to translate requirements into scalable architectures, leadi...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$199K - $270K *

Tackle the complexities of backend engineering by developing robust API integrations, building ETL pipelines, and collaborating with cross-functional teams to enhance system reliability and performanc...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Champion the development of impactful software solutions, collaborating across teams to enhance educational tools. Take ownership of code quality and performance, while mentoring peers and leveraging...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$97K - $139K *

Join a dynamic team to develop full-stack applications that enhance user engagement and drive growth on a global scale, leveraging data and AI to create impactful features for millions of Quora users...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the charge in developing scalable audience solutions by integrating predictive models and data workflows. Collaborate with cross-functional teams to enhance audience activation and ensure reliabl...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Technical Services

$157K - $180K *

Join a team that's driving innovation by building AI-powered tools for a vibrant community of diverse software engineers. You'll blend hands-on engineering with community management to enhance technic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $215K *

Drive innovative web services through technical leadership and collaboration. Shape the architecture of scalable products, mentor engineers, and tackle challenging problems to enhance user experiences...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Drive operational excellence by designing and enhancing technology systems that elevate customer experience. Lead cross-functional initiatives, leveraging AI and automation to create scalable solution...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Champion the maintenance and support of existing software products while ensuring stability and responsiveness to customer needs. Collaborate across teams to enhance features and contribute to future...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive the development of scalable software platforms, leveraging AI tools and modern methodologies to enhance performance and quality. Collaborate cross-functionally to build impactful solutions that...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $252K *

Shape the future of national security by ensuring high performance and reliability of AI and data analytics platforms. Leverage your SRE expertise to optimize mission-critical systems within secure Az...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$88K - $154K *

Unlock potential by joining a dynamic team as you craft and execute comprehensive software test plans for mission-critical applications, ensuring quality and reliability in a fast-paced, innovative en...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Inspire your career by joining a dynamic team focused on mobile automation, designing frameworks and enhancing test coverage for iOS and Android apps. Collaborate closely with engineering and product...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Transform your career by leading platform engineering initiatives that enhance developer experience and operational excellence. Drive technical ownership across the software lifecycle, shaping the pla...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Optimize runtime authorization strategies across diverse segments, driving technical wins and enabling Sales Engineers. Leverage deep IAM and PAM expertise to deliver impactful solutions, ensuring com...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$112K - $125K *

Unlock your potential as a software engineer, driving innovation in AI solutions. Collaborate with a dynamic team to develop and deploy cutting-edge software that enhances productivity and automates w...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$135K - $160K *

Lead the architecture of certificate lifecycle management capabilities that enhance security across complex environments, collaborating with product and engineering teams to build scalable systems tha...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Innovate solutions as you design and develop scalable UI applications, ensuring top-tier user experience and performance. Collaborate across teams, enforce coding standards, and lead projects to deliv...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.