Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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$135K - $160K *

Champion innovation by leading engineering efforts within established companies. Drive modernization, mentor teams, and enhance software delivery while leveraging diverse tech stacks to deliver impact...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$254K - $297K *

Elevate customer experiences by diagnosing and resolving complex technical challenges. Contribute directly to product engineering initiatives while collaborating with strategic customers and internal...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$114K - $252K *

Lead the charge in architecting and implementing a cutting-edge AI platform for federal oversight, driving innovation with technical leadership and ensuring security and compliance across complex clou...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$117K - $195K *

Join a team that's developing cutting-edge avionics architectures for diverse missions. Leverage your expertise in command and data handling to optimize system performance and ensure seamless integrat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Join our dynamic Delivery team to design and develop robust data pipelines, leveraging cloud technologies and distributed systems while ensuring optimal performance and scalability for our clients' da...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$193K - $309K *

Pioneer innovative developer experiences by setting technical direction and enhancing workflows. Collaborate across teams to design solutions that empower engineers, leveraging AI to redefine software...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$185K - $225K *

Launch innovative full-stack solutions, owning features from backend to UI. Collaborate with a remote team to enhance agent workflows and ensure secure, reliable experiences in a regulated financial e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$102K - $136K *

Empower your career by designing and delivering scalable software solutions in a dynamic environment. Collaborate with cross-functional teams to enhance healthcare supply chain products using modern t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $153K *

Lead the enhancement and administration of enterprise endpoint security technologies, collaborating with cross-functional teams to optimize security processes and improve detection capabilities in a g...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$171K - $248K *

Elevate fan support through innovative technology and collaborative leadership. As a technical manager, drive the vision and execution for a best-in-class support experience, empowering your team to e...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$209K - $273K *

Grow your career with a technical leadership role tackling complex challenges while mentoring others and collaborating on impactful projects across multiple engineering teams, elevating standards and...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$132K - $174K *

Empower your career with hands-on technical leadership, driving innovation and excellence in healthcare systems. Lead a talented team, mentoring engineers while architecting scalable, secure solutions...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $190K *

Innovate software solutions in dynamic environments, collaborating with operators and engineers to rapidly prototype and deploy mission-critical capabilities. Leverage your technical expertise to inte...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$166K - $230K *

Champion the development of innovative backend and full-stack solutions, leading complex projects that enhance borrower experiences. Collaborate with cross-functional teams to deliver high-quality, sc...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Partner with us to deliver tailored solutions and in-depth demos, supporting a dynamic sales pipeline. Leverage your technical expertise to drive customer success and collaborate with teams to enhance...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$127K - $213K *

Transform integration solutions by designing and developing robust MuleSoft applications. Collaborate with cross-functional teams to ensure high-quality delivery and optimize performance while mentori...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$143K - $241K *

Collaborate with cross-functional teams to design and implement scalable data solutions, optimize performance, and enhance software architecture while adhering to coding standards and leveraging AI to...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$144K - $241K *

Lead the charge in architecting and enhancing AI systems that empower global journalism. Drive technical direction, ensure system scalability, and mentor engineers while shaping the future of content...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$110K - $130K *

Shape the future of customer solutions by leveraging technical expertise to design, implement, and optimize innovative open-source solutions, engaging with clients and directly impacting product direc...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Transform the foundational platform that powers diverse products by leading design and evolution efforts, driving product velocity, and ensuring reliability and scalability for a variety of deployment...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$209K - $273K *

Drive innovation by owning customer-facing products end to end, leading technical strategy, and shaping product direction. Collaborate across teams to build AI-native experiences that enhance user eng...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$120K - $140K *

Transform your career by leading complex design change projects from inception to execution. Collaborate with cross-functional teams, manage substantial budgets, and drive innovation in a fast-paced e...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $220K *

Champion infrastructure innovations by owning the AI Gateway system end-to-end, making pivotal decisions on performance, scaling, and model integrations within a high-impact engineering team...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $135K *

Join a team that's shaping the future of digital services for Veterans. As a Senior Software Engineer, you'll design and maintain scalable applications, collaborate with cross-functional teams, and me...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $155K *

Unlock potential by leading technical delivery on multiple projects while mentoring teams and driving innovative software solutions with AI tools, ensuring quality and efficiency across cloud architec...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.