Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$110K - $130K *

Empower your career as a Platform Engineer, driving innovation in system architecture and cloud technologies. Collaborate with cross-functional teams to enhance platform efficiency and guide junior en...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$170K *

Engage with a dynamic team to elevate engineering excellence by leading managers and analysts, ensuring project execution aligns with performance goals, and driving professional growth across the regi...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$95K - $115K *

Support and enhance critical infrastructure for a modern healthcare platform, ensuring system reliability and performance through Windows Server administration, PowerShell automation, and IIS support...

Today

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join a team that's enhancing healthcare interoperability through infrastructure engineering. Contribute to system reliability and performance while supporting the Epic Payer Platform with Windows Serv...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that’s redefining frontend development by creating dynamic, responsive websites and engaging email campaigns. Collaborate across brands, utilizing React, Next.js, and modern web technologi...

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $135K *

Drive impactful mortgage analysis through collaboration with cross-functional teams. Leverage industry expertise to optimize integrations, enhance product functionality, and document processes for tra...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$239K - $298K *

Drive the evolution of Mercury's services platform by defining standards for deployment, authentication, and observability. Collaborate across teams to enhance infrastructure while mentoring engineers...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Transform data landscapes by designing and maintaining robust systems that empower organizations to harness large data volumes, ensuring accessibility, reliability, and compliance while collaborating...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$212K - $222K *

Champion client success as you lead Aera solution deployments, building trusted relationships with executives to drive value and Decision Intelligence roadmaps while managing project delivery and fost...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$130K - $155K *

Architect scalable software solutions while driving innovation in AI-enabled engineering workflows. Collaborate with cross-functional teams to enhance code quality and operational outcomes, ensuring s...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Lead the charge in technical excellence by independently managing complex DDC implementations, mentoring junior engineers, and driving continuous improvement initiatives in mission-critical data cente...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $187K *

Innovate the future of AI security by designing and implementing robust defenses against adversarial threats, ensuring the integrity of AI systems while fostering innovation and collaboration across c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $225K *

Pioneer innovative solutions as a Machine Learning Engineer, fine-tuning transformer models and deploying real-time automation pipelines, collaborating with top talents to tackle complex, data-driven...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Join a collaborative team as a technical lead, driving Angular and Python engineering. Oversee technical delivery, mentor engineers, and ensure high standards in product quality through hands-on leade...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$161K - $242K *

Join a team that's driving strategic initiatives and digital transformation. Collaborate with senior leaders to tackle complex challenges, influence decision-making, and ensure successful execution of...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$143K - $196K *

Champion innovative solutions in healthcare coding by leading cross-functional teams, optimizing product strategies, and enhancing customer experiences through data-driven insights and agile methodolo...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Drive technical leadership and customer success by leveraging expertise in polyiso insulation, ensuring optimal product performance and collaborating across engineering, sales, and operations to meet...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Join our team to architect and manage cloud infrastructure, tackling complex data security challenges while improving automation and enhancing stability for enterprise solutions. Ideal for hands-on pr...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Staffing

$172K - $225K *

Champion innovative solutions and elevate our engineering teams' capabilities by mentoring and guiding strategic product developments, enhancing performance, and ensuring customer satisfaction through...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$145K - $175K *

Deliver robust AI solutions by designing and implementing core agents for a cutting-edge enterprise platform. Collaborate with cross-functional teams to ensure high-quality, production-ready deploymen...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $120K *

Join a team that drives innovation in renewable natural gas engineering. Contribute to improving the safety, reliability, and profitability of RNG facilities while supporting operational excellence th...

Reposted today

  •   5 - 7 years exp.  •   Energy & Utilities

$153K - $166K *

Drive security excellence by partnering with product teams to embed security practices throughout the development lifecycle, focusing on AI features and risk mitigation to protect millions of users gl...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$125K - $160K *

Shape the future of global merchandising technology by leading engineering efforts, driving modernization, and ensuring high-quality delivery across diverse platforms. Collaborate with teams to implem...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Transform the future of data engineering by leading innovative solutions that enhance data collection, storage, and analytics. Collaborate with a high-performing team to drive impactful results across...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Join a team that's at the forefront of machine learning and search innovation. Collaborate with cross-functional teams to develop scalable ML systems that enhance user experiences and drive impactful...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.