Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$175K - $250K *

Shape the cloud infrastructure for AI agents, ensuring secure, scalable solutions that enhance customer workflows. Lead architectural decisions, establish standards, and drive innovation in a dynamic...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate marketing efficiency by designing and implementing AI-driven applications on a robust data platform. Collaborate across teams to optimize workflows, ensuring data integrity and security while...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$119K - $224K *

Unlock innovation by developing advanced blockchain protocols and cryptographic solutions. Collaborate with cross-functional teams to design, implement, and optimize a high-performance settlement engi...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$98K - $206K *

Lead the charge in designing and enhancing software applications that support mission-critical operations, collaborating with diverse teams to drive innovative solutions and improve performance across...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Shape the future of semantic technologies by guiding teams in architecting scalable data solutions. Collaborate across functions to define ontologies and drive enterprise-wide data strategy while ment...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Unlock potential by leading our Site Reliability Engineering team, ensuring the reliability and performance of our cloud-native platform. Drive technical excellence, cultivate a high-performance cultu...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$244K - $279K *

Empower teams to innovate AI solutions that transform banking experiences. Collaborate across functions to design, develop, and optimize cutting-edge AI systems, driving responsible and impactful tech...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $160K *

Champion innovative data solutions by leading migrations and optimizing access patterns. Collaborate with product engineers to drive the evolution of our database infrastructure, contributing to robus...

US-AnywhereRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$135K - $160K *

Drive innovation in vendor risk management by developing full-stack solutions to enhance enterprise security. Collaborate across teams to build seamless experiences and shape how businesses manage thi...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$106K - $284K *

Reimagine application development by leading architecture and scaling core systems. Drive AI integration, mentor teams, and ensure operational excellence across full-stack technologies while deliverin...

US-AnywhereRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $260K *

Shape the future of digital engineering by designing and implementing innovative software solutions. Collaborate with cross-functional teams to enhance system performance and mentor junior developers...

US-AnywhereRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$128K - $252K *

Lead the charge in building and managing high-performing software engineering teams. Drive innovation, optimize processes, and deliver high-quality applications while fostering a culture of excellence...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $125K *

Advance your career by ensuring optimal database performance and security. Collaborate with cross-functional teams to implement robust architecture, perform upgrades, and support database applications...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$63K - $111K *

Engineer exceptional electronic security systems while managing logistics and asset accountability. Collaborate with teams to maintain security protocols, perform maintenance, and adapt to dynamic env...

US-AnywhereRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$170K - $210K *

Unlock potential by leading the development of data-intensive applications. Leverage your technical expertise to mentor the team, enhance product features, and tackle complex system challenges while e...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$95K - $115K *

Elevate your career by managing and optimizing critical systems. Leverage your Linux expertise and automation skills to enhance network performance and security while mentoring a dynamic team in a mis...

1 week ago

  •   5 - 7 years exp.  •   Staffing

$130K - $155K *

Elevate engineering excellence within an agile team by architecting and developing robust coding frameworks and securing high-quality market-leading technology solutions that drive efficiency and perf...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Join a dynamic team to build and automate security controls across our infrastructure. You'll manage host hardening, vulnerability assessments, and compliance, leveraging AI tools to enhance security...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$186K - $242K *

Empower innovation at a rapidly growing team, leading API architecture and integrations. Collaborate across teams to enhance platform capabilities while mentoring engineers and ensuring system reliabi...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Partner with us to bridge technical solutions and customer needs in a dynamic, cross-functional role. Utilize your expertise to drive adoption of AI agents, influencing product roadmaps and enhancing...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $144K *

Lead the charge in designing and implementing advanced building automation systems for critical infrastructure projects, ensuring seamless integration and optimal performance while managing teams and...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Technical Services

$125K - $155K *

Join our dynamic team as a Senior Solutions Engineer, where you'll leverage your technical expertise to drive pre-sales activities, engage with clients, and deliver tailored solutions that enhance bus...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $119K *

Support the development and implementation of technical solutions for complex engineering projects, ensuring effective communication and operational excellence in GMP environments while driving contin...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $207K *

Elevate your career by designing and building essential SDKs that empower engineering teams to create reliable, observable distributed systems. Collaborate across teams to enhance developer experience...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$96K - $143K *

Unlock potential by leading end-to-end software deployment and integration. Collaborate with clients to assess environments, configure hardware, and ensure seamless operational transitions while provi...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.