Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$80K - $95K *

Join a team that's dedicated to enhancing automation solutions through troubleshooting, programming, and customer collaboration. Leverage your skills to improve machinery performance and ensure seamle...

US-AnywhereRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$250K - $349K *

Unlock potential by leading technical direction for Core DevOps, improving CI/CD systems while driving productivity, quality, and AI innovations in a fast-paced environment impacting millions of users...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $160K *

Lead the establishment of a Production Site Reliability Engineering team, ensuring high availability and performance of web applications while driving operational excellence and strategic improvement...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $155K *

Collaborate to design and develop scalable solutions for modern data platforms, utilizing Python and cloud technology. Drive innovation through AI-assisted tools, while building robust data pipelines...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Develop and deploy AI-driven solutions to enhance operational performance and efficiency across manufacturing and business processes, collaborating with multiple teams to address challenges and optimi...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$180K - $250K *

Join a dynamic team defining and optimizing robust networking infrastructure, ensuring fast, reliable, and secure connectivity across diverse environments including public cloud and private compute cl...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $185K *

Lead high-performing software engineering teams to modernize customer-facing applications, enhance operational efficiency, and drive AI-enabled practices, ensuring alignment with business objectives a...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$95K - $115K *

Drive impactful technical projects by collaborating with business partners to implement solutions, manage resources, and ensure project success within defined methodologies and budgets. Foster a dynam...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$96K - $105K *

Transform automated pharmacy systems by diagnosing and solving complex engineering challenges. Leverage your expertise to enhance reliability and efficiency across multiple locations while leading con...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Join a team that's redefining operational efficiency through AI and automation. As a Senior AI & Automation Engineer, you'll develop intelligent solutions that enhance workflows and drive measurable i...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's redefining automotive innovation by leading system requirements for software-defined vehicles. Collaborate across functions to ensure clarity and traceability in requirements, drivi...

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$76K - $135K *

Advance your career by supporting critical data center operations, providing real-time maintenance and troubleshooting on electrical and mechanical systems, while working in a fast-paced, team-oriente...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$135K - $160K *

Transform enterprise AI systems by designing and delivering autonomous agents. Leverage your expertise in LLMs and Glean to create reliable, secure solutions that scale, while owning the entire lifecy...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the development and operation of next-gen GraphQL infrastructure, ensuring performance, security, and reliability while mentoring teams and collaborating cross-functionally to deliver outstanding...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $145K *

Join a dynamic team to design and implement cloud security solutions, enhancing information security and compliance while mitigating cyber threats across the organization. Drive innovation and improve...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $216K *

Lead the charge in managing a software engineering team, driving the design and delivery of secure satellite ground communication services while fostering best practices and ensuring alignment with mi...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$90K - $100K *

Join a team that's dedicated to enhancing data pipeline stability and server administration for enterprise analytics systems. Support the transition of legacy data models into Tableau while ensuring c...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$110K - $130K *

Elevate software security through analysis, development, and vulnerability management, ensuring application safety and enhancing user experience in a dynamic call center environment while collaboratin...

US-AnywhereRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$120K - $145K *

Drive technical pre-sales and implementation for innovative API and AI products, serving as a key liaison between customers and engineering teams to enhance AI-driven discovery experiences in the medi...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Empower progress in product security by embedding advanced safeguards within every development phase. Collaborate with engineering teams to build AI-enhanced security tooling and enhance proactive ris...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $210K *

Shape the future of data engineering by owning our core infrastructure and driving the technical direction of data platforms. Collaborate across teams to ensure best practices in data modeling, pipeli...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Lead a strategic portfolio within a large-scale transformation, ensuring delivery excellence across multiple programs and managed services while driving innovation through AI-native practices and oper...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $95K *

Bring your expertise to a hands-on technical engineering role that tackles real-world system issues, builds new solutions, and collaborates across teams to enhance application performance and operatio...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Transportation

$110K - $135K *

Unlock excellence in PCB design and manufacturing by leading DFM initiatives, developing complex multilayer layouts, and shaping best practices across engineering teams to enhance product performance...

US-AnywhereRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$180K - $235K *

Lead the charge in developing robust backend applications, driving complex projects from design to launch. Collaborate across teams, mentor junior engineers, and tackle architectural challenges to enh...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.