Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$140K - $190K *

Unlock end-to-end software solutions by designing and developing scalable features at the intersection of healthcare and technology. Collaborate with cross-functional teams to rapidly deploy impactful...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$63K - $111K *

Join a team that's dedicated to transforming infrastructure; enhance your skills while providing essential engineering support to construction crews nationwide with a focus on electrical systems and c...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$63K - $111K *

Innovate your engineering career by supporting critical infrastructure projects across various FAA programs, ensuring compliance with standards and enhancing safety through hands-on fieldwork and coll...

RemoteRemote

1 month ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$87K - $253K *

Accelerate your career by designing and operating comprehensive production systems. Lead multidisciplinary teams to deliver AI-native solutions, transforming ambiguous challenges into measurable outco...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$87K - $253K *

Champion the design and operation of comprehensive production systems, integrating application engineering, cloud infrastructure, and AI capabilities. Lead multidisciplinary teams to transform ambiguo...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$87K - $253K *

Advance enterprise solutions by designing and operating comprehensive production systems. Collaborate across engineering disciplines to tackle complex challenges, integrating AI capabilities while lea...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$160K - $180K *

Address complex healthcare data integration by designing and implementing robust data models. Collaborate with cross-functional teams to transform raw data into actionable insights swiftly. Leverage y...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $185K *

Champion the development of scalable data platforms, leading cross-functional initiatives and enhancing AI-assisted analytics. Collaborate with teams to drive technical direction and improve system pe...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Join us to architect and lead the design of complex electromechanical systems that revolutionize pharmacy automation, ensuring precision and reliability while scaling production to meet nationwide dem...

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$153K - $213K *

Take ownership of a customer-facing product area, driving strategy and execution. Collaborate cross-functionally to enhance user experience, leverage AI, and achieve key performance metrics while deli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$163K - $224K *

Advance innovative backend systems for a cutting-edge experimentation platform, driving impactful decisions through large-scale data solutions in a collaborative team environment, while designing and...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Champion the development of an autonomous AI platform through full-stack engineering, enhancing multi-agent systems and ensuring robust quality and safety standards across production deployments...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $125K *

Join a dynamic team to design and support enterprise infrastructure platforms focusing on automation, reliability, and security, while optimizing system performance and driving continuous improvement...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$122K - $214K *

Elevate enterprise AI infrastructure by leading the design and strategy for scalable compute platforms, ensuring reliability and security while driving innovation across cross-functional teams and ini...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$145K - $175K *

Transform your career by architecting secure, scalable Azure solutions that drive modern application delivery. Collaborate with diverse teams to develop automation and enhance cloud services while lev...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$244K - $279K *

Unlock potential by designing and optimizing innovative AI systems, collaborating with cross-functional teams to deliver impactful AI solutions that transform business processes across a diverse enter...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$116K - $219K *

Unlock your potential as a senior contributor in software quality engineering, driving high-quality solutions through collaboration, automation, and Agile practices. Enhance product reliability and ef...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$112K - $149K *

Drive innovation by building and maintaining data pipelines and governance policies in a hybrid cloud environment. Collaborate with a small team to ensure reliable data flow and access control, enhanc...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$137K - $160K *

Engineer secure and resilient multi-cloud environments while collaborating with product teams. Adapt designs to support rapid change in a late-stage startup, ensuring safety and performance in AI-driv...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform the infrastructure for a groundbreaking healthcare platform by optimizing cloud solutions, implementing CI/CD, and collaborating with cross-functional teams to enhance clinical AI/ML offerin...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's driving software quality through innovative automation frameworks. As a key player, you'll lead QA efforts, mentor engineers, and ensure high-quality, reliable software in an Agile...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$184K - $356K *

Transform data processing architectures by optimizing performance and efficiency. Collaborate with diverse teams to enhance user experiences and drive innovation in hardware-software co-design for cut...

RemoteRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $130K *

Lead electrical engineering efforts for complex commercial projects, ensuring innovative design solutions and multidisciplinary coordination. Mentor junior staff while delivering projects on time and...

2 days ago

  •   5 - 7 years exp.  •   Staffing

$120K - $130K *

Advance your career by leading electrical engineering efforts for complex commercial projects. Drive innovative design solutions, mentor junior staff, and ensure project success from concept to comple...

2 days ago

  •   5 - 7 years exp.  •   Staffing

$120K - $130K *

Shape the future of commercial engineering by leading complex electrical design projects. Drive innovation, mentor talent, and ensure successful project delivery while collaborating with multidiscipli...

3 days ago

  •   5 - 7 years exp.  •   Staffing

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.