Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$116K - $219K *

Unlock your potential as a senior contributor in software quality engineering, driving high-quality solutions through collaboration, automation, and Agile practices. Enhance product reliability and ef...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$137K - $160K *

Engineer secure and resilient multi-cloud environments while collaborating with product teams. Adapt designs to support rapid change in a late-stage startup, ensuring safety and performance in AI-driv...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform the infrastructure for a groundbreaking healthcare platform by optimizing cloud solutions, implementing CI/CD, and collaborating with cross-functional teams to enhance clinical AI/ML offerin...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's driving software quality through innovative automation frameworks. As a key player, you'll lead QA efforts, mentor engineers, and ensure high-quality, reliable software in an Agile...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$184K - $356K *

Transform data processing architectures by optimizing performance and efficiency. Collaborate with diverse teams to enhance user experiences and drive innovation in hardware-software co-design for cut...

US-AnywhereRemote

Reposted today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $130K *

Lead electrical engineering efforts for complex commercial projects, ensuring innovative design solutions and multidisciplinary coordination. Mentor junior staff while delivering projects on time and...

Yesterday

  •   5 - 7 years exp.  •   Staffing

$120K - $130K *

Advance your career by leading electrical engineering efforts for complex commercial projects. Drive innovative design solutions, mentor junior staff, and ensure project success from concept to comple...

2 days ago

  •   5 - 7 years exp.  •   Staffing

$120K - $130K *

Shape the future of commercial engineering by leading complex electrical design projects. Drive innovation, mentor talent, and ensure successful project delivery while collaborating with multidiscipli...

2 days ago

  •   5 - 7 years exp.  •   Staffing

$120K - $145K *

Take ownership of automating workflows across teams by building AI agents using Claude and Microsoft Copilot. Collaborate with various departments to identify automation opportunities, ensuring securi...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Advance your career by leading high-level software design and analysis initiatives, collaborating with product managers and developers to create innovative solutions for both new and existing SaaS sys...

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$141K - $177K *

Join us to shape the future of cybersecurity by leading product vision and strategy for our innovative Autonomous and Continuous pentesting platform, driving impactful solutions that enhance security...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$100K - $120K *

Drive security excellence by managing identity access, external testing, and compliance processes. Collaborate with teams to enhance AWS security and develop scalable policies, ensuring robust protect...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading complex software development initiatives, providing strategic technical guidance, and mentoring teams to drive innovative solutions in a collaborative environment...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$62K - $103K *

Engage with clients to implement and manage endpoint computing infrastructure, provide training, and resolve technical issues. Collaborate with teams to enhance client service and drive professional g...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the development of edge software, ensuring robust design and seamless integration across systems. Drive quality standards, mentor engineers, and manage software behavior in the field, all while m...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Take ownership of business intelligence software development, optimizing ETL pipelines, and enhancing data-driven decision-making across multiple environments while ensuring compliance and security fo...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$224K - $431K *

Transform the landscape of CUDA Math Libraries by leading a dynamic engineering team focused on platform expansion and performance, ensuring high-quality support across specialized computing environme...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$106K - $284K *

Elevate your career by leading a dynamic engineering team to build scalable, cloud-native solutions within the Salesforce ecosystem, driving innovation across key business areas like Marketing, Sales...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate enterprise-level IT operations by providing Tier 3 systems administration, security, and support for on-premises and cloud environments, ensuring compliance and optimal performance across mult...

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's at the forefront of identity & authentication technologies, serving as a key technical expert. Your role enhances security and stability through innovative solutions, ensuring relia...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$224K - $356K *

Transform AI inference by leading the development of advanced GPU-accelerated software, driving feature innovation, and enhancing customer adoption in a collaborative open-source environment...

US-AnywhereRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$120K - $180K *

Join a team that's dedicated to delivering exceptional project controls for data centers. Leverage your expertise in CPM scheduling and collaborate with diverse stakeholders to drive project success a...

4 days ago

  •   5 - 7 years exp.  •   Staffing

$80K - $95K *

Join a team that's dedicated to enhancing automation solutions through troubleshooting, programming, and customer collaboration. Leverage your skills to improve machinery performance and ensure seamle...

US-AnywhereRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$250K - $349K *

Unlock potential by leading technical direction for Core DevOps, improving CI/CD systems while driving productivity, quality, and AI innovations in a fast-paced environment impacting millions of users...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $160K *

Lead the establishment of a Production Site Reliability Engineering team, ensuring high availability and performance of web applications while driving operational excellence and strategic improvement...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.