Explore $100K+ Jobs in Ohio

Discover professional opportunities across Ohio with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and technology roles to positions in finance, healthcare, engineering, and operations. Whether you’re considering a move to a major city or looking for opportunities closer to home, explore roles that match your experience and career goals.

Where to Find High-Paying Jobs in Ohio

Ohio’s job market spans major metropolitan areas and growing regional economies. Explore opportunities in Columbus, Cleveland, Cincinnati, and other communities throughout the state. Employers across industries seek experienced professionals for roles in corporate leadership, technology, healthcare, manufacturing, financial services, and more. Available positions and compensation vary by employer, location, and qualifications.

Industries and Career Paths

Ohio offers career possibilities across established and emerging sectors. Depending on your background, you may find senior-level opportunities in business management, software and information technology, healthcare administration, engineering, supply chain, sales, and finance. Use Ladders to search current listings and identify roles suited to your skills and professional experience.

Find the Right Ohio Opportunity

Make your search more focused by filtering listings by location, job title, industry, and other preferences. Review each posting for its responsibilities, requirements, and compensation details, then tailor your application to highlight relevant accomplishments. New opportunities are added over time, so check back regularly for the latest $100K+ jobs in Ohio.

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$135K - $160K *

Join a team that's responsible for building and maintaining a scalable, secure, and performant Linux infrastructure through automation and modern tooling, ensuring high availability and adherence to b...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$124K - $196K *

Transform customer experiences by building robust REST APIs and CI/CD pipelines. Collaborate with cross-functional teams to deliver high-quality code and impactful features, ensuring reliability and s...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Shape the future of integrations by serving as the technical bridge between CXone and partners, creating tools, sample applications, and a framework for efficient integration while addressing partner...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$168K - $253K *

Build robust APIs and backend systems as a key player in our AI grocery product. Lead architectural development, partner with cross-functional teams, and grow impactful solutions for grocery stores na...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$207K - $283K *

Optimize security measures for cloud-native environments, collaborating closely with development teams to conduct threat modeling, implement scalable security practices, and enhance detection and resp...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join our team to model systems that support critical missions. Lead and mentor junior engineers while collaborating on innovative solutions. Leverage your expertise to shape system analysis and contri...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$173K - $233K *

Unlock innovative solutions as you collaborate across teams to enhance user experiences on mobile and web platforms. Drive impactful projects, support product development, and contribute to a thriving...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$122K - $240K *

Develop and operationalize AI solutions by building secure, scalable data and feature layers for Human Capital products. Collaborate with cross-functional teams to deliver reliable pipelines and servi...

2 days ago

  •   Less than 5 years exp.  •   Business Services

$122K - $240K *

Join a team that's redefining Human Capital through innovative AI solutions. Collaborate with experts to design, build, and operationalize scalable AI products, ensuring data governance and security w...

2 days ago

  •   Less than 5 years exp.  •   Business Services

$122K - $240K *

Lead the charge in designing and delivering AI solutions that enhance Human Capital products. Collaborate with cross-functional teams to build scalable, secure, and reliable data pipelines and LLM app...

2 days ago

  •   Less than 5 years exp.  •   Business Services

$152K - $179K *

Join a team that's building innovative backend services for stablecoin issuance and operations. Collaborate with cross-functional teams to enhance adoption and drive growth through reliable, well-test...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Champion the development of cutting-edge infrastructure for AI systems, focusing on Kubernetes management, automated deployments, and reliable scaling to support enterprise demands across multiple clo...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Unlock innovation by designing backend services in Python and enhancing AI-powered search solutions. Collaborate in agile teams to create impactful enterprise search products while mentoring peers and...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Transform identity and access management by executing daily operations, supporting AI tooling, and managing SaaS vendor administration. This role offers hands-on experience and a clear growth path tow...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Engineer resilient backend solutions for privileged account discovery, enhancing security while navigating complex, customer-deployed environments. Collaborate on data-processing workflows using cutti...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$108K - $130K *

Unlock potential by leading a global team of network engineers while overseeing enterprise network solutions. Engage in hands-on design and management, addressing complex technical challenges and driv...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Transform automation capabilities by leading innovative engineering projects and collaborating across teams. Drive continuous improvement in operations and ensure regulatory compliance throughout proj...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$105K - $231K *

Grow your career with a mission-driven team designing secure, scalable cloud software solutions for complex operations, leveraging innovative technologies in a collaborative environment focused on exc...

US-AnywhereRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Grow your career with us by developing cutting-edge UEFI BIOS and bootloader software. Collaborate closely with hardware engineers to drive innovation across complex embedded systems in a dynamic, int...

US-AnywhereRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Join a team that's shaping scalable backend systems to enhance pharmacy operations with AI-driven solutions, driving performance and reliability while mentoring engineers and influencing technical dir...

US-AnywhereRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Accelerate growth by designing scalable backend systems that enhance pharmacy operations and logistics. Shape critical platforms through AI-driven insights, strong engineering practices, and collabora...

US-AnywhereRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$126K - $162K *

Lead the charge in advanced ICT design for mission-critical data centers. Collaborate with stakeholders to oversee complex projects, manage resources, and drive innovation through technology adoption...

US-AnywhereRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$120K - $145K *

The Technical Support Engineering Manager will lead a team of Support Engineers and Product Experts to resolve complex technical issues and enhance customer experience. This role involves collaboratin...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$124K - $134K *

Innovate and optimize our core fintech systems, leveraging AI-driven technologies while owning end-to-end product development. Collaborate with cross-functional teams to ensure impactful user experien...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Develop cutting-edge RF systems and components to enhance communication technologies. Collaborate with teams on design, testing, and optimization while ensuring compliance with industry standards and...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Ohio?question toggle

    Listings may include professional and senior-level roles in fields such as technology, healthcare, finance, engineering, manufacturing, sales, and business operations. Job availability depends on current employer postings.

  • Which Ohio cities have high-paying job opportunities?question toggle

    Explore listings in Columbus, Cleveland, Cincinnati, and other Ohio cities and communities. Use location filters to find opportunities in the areas that work for you.

  • How can I search for jobs in Ohio on Ladders?question toggle

    Browse Ohio job listings and narrow your results by location, job title, industry, or other available filters. Check each posting for salary information, qualifications, and application instructions.

  • Are Ohio jobs on Ladders guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, since pay and eligibility requirements vary by role and employer.