Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$77K - $108K *

Innovate high-performance AI network fabrics for accelerated computing. Engage with clients to deliver tailored solutions, ensuring optimal configurations for GPU clusters and data-center infrastructu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Transform legacy technology by leading modernization efforts, utilizing your deep expertise in CA Gen and COBOL. Collaborate within a dynamic team to design specifications that support the successful...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $250K *

Shape the cloud infrastructure for AI agents, ensuring secure, scalable solutions that enhance customer workflows. Lead architectural decisions, establish standards, and drive innovation in a dynamic...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate marketing efficiency by designing and implementing AI-driven applications on a robust data platform. Collaborate across teams to optimize workflows, ensuring data integrity and security while...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Shape the future of semantic technologies by guiding teams in architecting scalable data solutions. Collaborate across functions to define ontologies and drive enterprise-wide data strategy while ment...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Join a dynamic team to enhance Safety PLC compliance and develop robust control solutions through rigorous auditing and countermeasure strategies, ensuring adherence to industry standards and fosterin...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Elevate your career as a Principal Engineer, driving innovation in logistics systems through application design, legacy migrations, and seamless vendor integrations to enhance operational efficiency a...

Yesterday

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Unlock potential by leading our Site Reliability Engineering team, ensuring the reliability and performance of our cloud-native platform. Drive technical excellence, cultivate a high-performance cultu...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$244K - $279K *

Empower teams to innovate AI solutions that transform banking experiences. Collaborate across functions to design, develop, and optimize cutting-edge AI systems, driving responsible and impactful tech...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$190K - $300K *

Champion innovative network solutions by leading pre-sales efforts, collaborating with sales teams, and driving technical strategies to enhance client relationships and deliver tailored solutions in n...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $160K *

Champion innovative data solutions by leading migrations and optimizing access patterns. Collaborate with product engineers to drive the evolution of our database infrastructure, contributing to robus...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$217K - $303K *

Innovate the future of iOS development by architecting scalable solutions for Reddit's mobile app. Lead technical direction, mentor engineers, and enhance developer efficiency to support 100M+ DAUs wh...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Media

$120K - $184K *

Engineer scalable backend solutions for AI platforms, focusing on microservices, data design, and performance optimization. Collaborate with teams to ensure system reliability and integrate AI service...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Drive innovation in vendor risk management by developing full-stack solutions to enhance enterprise security. Collaborate across teams to build seamless experiences and shape how businesses manage thi...

RemoteRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Enterprise Technology

$106K - $284K *

Reimagine healthcare technology by leading the development of secure, scalable microservices. Collaborate with cross-functional teams to enhance digital solutions that transform patient experiences an...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $284K *

Join a team that’s redefining pharmacy and healthcare through innovative digital solutions. As a Staff Software Development Engineer, you'll lead in creating next-generation platforms, ensuring qualit...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $284K *

Champion the design and development of scalable applications, integrating AI and data systems. Lead technical strategy, mentor teams, and ensure operational excellence across the technology stack whil...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $284K *

Reimagine application development by leading architecture and scaling core systems. Drive AI integration, mentor teams, and ensure operational excellence across full-stack technologies while deliverin...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$106K - $260K *

Shape the future of digital engineering by designing and implementing innovative software solutions. Collaborate with cross-functional teams to enhance system performance and mentor junior developers...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $177K *

Lead a dynamic Managed Services Engineering team to enhance cloud operations, ensuring exceptional service delivery, compliance, and continuous improvement while driving team development and operation...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $185K *

Accelerate progress at the forefront of test automation, driving quality and performance through innovative strategies and frameworks. Collaborate within an agile team to enhance product scalability a...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$128K - $252K *

Lead the charge in building and managing high-performing software engineering teams. Drive innovation, optimize processes, and deliver high-quality applications while fostering a culture of excellence...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $125K *

Advance your career by ensuring optimal database performance and security. Collaborate with cross-functional teams to implement robust architecture, perform upgrades, and support database applications...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$130K - $155K *

Optimize the development and enhancement of communication ecosystems, focusing on document composition and workflow automation. Collaborate in an Agile environment to deliver high-quality solutions th...

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Drive the development and enhancement of AI-enabled AML transaction monitoring solutions, collaborating with cross-functional teams to ensure compliance and operational efficiency in financial crime r...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.