Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$115K - $275K *

Manage the delivery of GPU clusters for AI workloads by coordinating teams across engineering, networking, and operations. Develop strategies, manage risks, and ensure timely, quality launches to scal...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $125K *

Lead innovative design solutions as a Senior Design Engineer, transforming client needs into actionable broadcast system designs. Collaborate with global teams, mentor junior engineers, and ensure pro...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitality & Recreation

$112K - $149K *

Drive innovation by building and maintaining data pipelines and governance policies in a hybrid cloud environment. Collaborate with a small team to ensure reliable data flow and access control, enhanc...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$137K - $160K *

Engineer secure and resilient multi-cloud environments while collaborating with product teams. Adapt designs to support rapid change in a late-stage startup, ensuring safety and performance in AI-driv...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform the infrastructure for a groundbreaking healthcare platform by optimizing cloud solutions, implementing CI/CD, and collaborating with cross-functional teams to enhance clinical AI/ML offerin...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's driving software quality through innovative automation frameworks. As a key player, you'll lead QA efforts, mentor engineers, and ensure high-quality, reliable software in an Agile...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Optimize manufacturing systems by developing engineering standards and procedures. Collaborate on facility planning, workflow, and logistics to enhance production efficiency and solve complex issues i...

3 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$184K - $356K *

Transform data processing architectures by optimizing performance and efficiency. Collaborate with diverse teams to enhance user experiences and drive innovation in hardware-software co-design for cut...

RemoteRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Innovate within a dynamic team to automate and streamline Windows deployment, utilizing your expertise in scripting and system integration to enhance operational efficiency for a federal client...

Raleigh, NCRemote

4 weeks ago

  •   8 - 10 years exp.  •   Staffing

$120K - $145K *

Take ownership of automating workflows across teams by building AI agents using Claude and Microsoft Copilot. Collaborate with various departments to identify automation opportunities, ensuring securi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$141K - $177K *

Join us to shape the future of cybersecurity by leading product vision and strategy for our innovative Autonomous and Continuous pentesting platform, driving impactful solutions that enhance security...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$100K - $120K *

Drive security excellence by managing identity access, external testing, and compliance processes. Collaborate with teams to enhance AWS security and develop scalable policies, ensuring robust protect...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $128K *

Lead project execution initiatives, ensuring timely delivery while maintaining safety, quality, and customer satisfaction. Collaborate across teams to optimize resource management and stakeholder enga...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Unlock potential by collaborating with cross-functional teams to analyze business needs and translate them into technical specifications for Pega implementations, ensuring effective solutions and camp...

2 days ago

  •   Less than 5 years exp.  •   Transportation

$224K - $431K *

Transform the landscape of CUDA Math Libraries by leading a dynamic engineering team focused on platform expansion and performance, ensuring high-quality support across specialized computing environme...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$106K - $284K *

Elevate your career by leading a dynamic engineering team to build scalable, cloud-native solutions within the Salesforce ecosystem, driving innovation across key business areas like Marketing, Sales...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Design and develop advanced electronic circuits for innovative medical devices. Collaborate with a multidisciplinary team to create solutions that enhance user experience, focusing on miniaturized bio...

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $170K *

Partner with us to lead the Body Main Systems team, driving innovative design and development of Body in White, Frame, and Closures Systems. Collaborate cross-functionally to ensure project success, m...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$113K - $169K *

Join a team that's shaping the future of software applications by providing technical expertise and customer solutions. Collaborate with cross-functional teams to drive product development and enhance...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Empower innovation by designing scalable architectures and frameworks. Collaborate with teams to deliver high-quality, defect-free code while mentoring peers and driving performance improvements throu...

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Lead the design and implementation of scalable technology frameworks, ensuring high-quality, defect-free code delivery. Collaborate across teams to optimize solutions and mentor peers while driving in...

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$174K - $209K *

Empower our team by driving innovative projects from concept to operation, enhancing the reliability and performance of our observability systems while collaborating in a fully remote environment focu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $126K *

Lead the charge in delivering exceptional data center solutions, guiding service delivery, and mentoring peers. Collaborate on diverse projects, optimize Cisco networking products, and enhance custome...

6 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$150K - $200K *

Unlock potential by driving enterprise agent solutions with Microsoft technologies. Collaborate on agent governance, lifecycle management, and secure operations, while translating designs into product...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Technical Services

$120K - $145K *

Join a team that's redefining infrastructure architecture and modernization. Lead initiatives across datacenter, cloud, and networking platforms while driving automation and security standards to enha...

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.