Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$120K - $145K *

Lead the charge in transforming our core banking platform by driving technical architecture and integration. Collaborate with cross-functional teams to deliver scalable solutions that enhance operatio...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $170K *

Elevate data engineering excellence by designing and implementing complex data solutions, mentoring engineers, and collaborating across teams to drive impactful data initiatives and architectural inno...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Optimize your skills in developing and maintaining SAS programs within a Mainframe environment. Take charge of code migration to cloud technologies and engage with stakeholders to create analytical so...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$146K - $234K *

Transform complex challenges into innovative solutions by leveraging expertise in RF communications, machine learning, and data analytics to enhance cybersecurity and network research for government a...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$111K - $163K *

Join a team dedicated to driving successful IT project outcomes through effective management methodologies, ensuring on-time and on-budget completion while aligning with business goals and fostering c...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$65K - $123K *

Optimize storage infrastructure by managing DASD and tape systems, ensuring efficient backups, migrations, and disaster recovery. Collaborate with clients and vendors while mentoring team members to e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Transform the client experience by building data platforms, AI apps, and workflows. Collaborate closely on real-world projects, making key decisions and enhancing your engineering skills in a dynamic...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Elevate your engineering career by leading innovative conveyor and sortation projects. Drive technical solutions from concept to execution, collaborating with cross-functional teams to enhance operati...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $140K *

Support the U.S. Marine Corps by bridging technical radio capabilities with defense needs. Collaborate with engineering teams to demonstrate and evaluate advanced communication systems in diverse oper...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$80K - $95K *

Champion the technical oversight of MK41 VLS systems installation, ensuring seamless integration and compliance through effective support in testing processes. Collaborate globally in diverse operatio...

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $180K *

Join a team that's shaping the future of DevOps by designing and implementing CI/CD pipelines with cutting-edge technologies. Collaborate with customers and cross-functional teams to enhance their Dev...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Unlock potential by leading pre-sales technical strategies that align solutions with client needs, driving revenue growth and retention through collaboration with sales teams and delivering tailored p...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Manage complex cybersecurity verification programs across large-scale data center projects. Lead coordination among diverse teams, ensuring operational readiness and technical integration throughout c...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Aerospace & Defense

$75K - $90K *

Transform business processes by designing and deploying automation solutions, collaborating with stakeholders to enhance efficiency and drive innovation across departments while adhering to enterprise...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$132K - $165K *

Shape the future of billing and collections by driving product strategy and enhancing user experiences. Collaborate with cross-functional teams to deliver reliable payment solutions that boost revenue...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$100K - $152K *

Accelerate your career by leading high voltage substation projects, collaborating with engineers to solve complex electrical issues, and enhancing your skills through peer learning and client interact...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$90K - $110K *

Empower quality assurance by developing AI-assisted automated tests, integrating them into CI/CD pipelines, and collaborating with cross-functional teams to enhance software reliability and release ef...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $190K *

Drive innovation by architecting scalable AI solutions that transform business processes across multiple domains. Collaborate with leaders to establish enterprise standards and governance frameworks f...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$88K - $105K *

Lead product marketing initiatives by crafting compelling messaging and strategies that drive customer engagement and adoption. Collaborate cross-functionally to ensure alignment and measure performan...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Drive the design and execution of a robust data architecture and engineering platform, ensuring secure, scalable solutions that empower analytics and product development while leading a talented team...

United StatesRemote

Yesterday

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform frontline manager development by leading strategic programs that enhance coaching, deal inspection, and pipeline management. Collaborate cross-functionally to drive consistent team performan...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Optimize technology solutions for supply chain operations by leading full-stack engineering efforts. Drive development, mentor teams, and align projects with business goals to deliver scalable web and...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$72K - $108K *

Shape the future of data analytics by designing and building a robust data layer in BigQuery. Collaborate with cross-functional teams to standardize metrics and enable self-service analytics, ensuring...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$123K - $172K *

Join our dynamic team to tackle real challenges in SaaS management, enhancing IT and Security ecosystems. Collaborate with talented professionals to build impactful software while leveraging AI for ef...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$230K - $360K *

Elevate customer success by designing and deploying innovative Gen AI and ML solutions. Collaborate with stakeholders to translate complex needs into impactful AI tools, ensuring reliability and busin...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.