Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$110K - $130K *

Join a team that's shaping innovative products by translating customer needs into actionable solutions. Collaborate with cross-functional teams to prioritize and deliver high-quality outcomes in a dyn...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$92K - $110K *

Shape the future of urban roadway design by leading complex projects, ensuring quality assurance, and mentoring a skilled team. Engage with clients and manage project scopes while leveraging your expe...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$188K - $282K *

Drive the architecture for customer data integration across digital platforms, ensuring secure ingestion and transformation. Collaborate with cross-functional teams to create scalable solutions that e...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Empower your career with senior-level expertise in data architecture and warehousing. Drive data integration and management, ensuring effective solutions for Occupational Environmental Health practice...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform cybersecurity practices by leading vulnerability management and penetration testing efforts. Collaborate with cross-functional teams to enhance security controls, reduce risks, and ensure ro...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$186K - $218K *

Lead the transformation of mobile experiences by developing native apps in Swift and Kotlin. Collaborate with product teams to enhance performance and architecture, driving innovation for millions of...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Unlock potential by joining a dynamic team to design and build AI-driven applications, collaborating directly with clients or enhancing their teams through your expertise in software development and e...

Jackson, MSRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $125K *

Champion data engineering excellence by designing and maintaining robust data pipelines and analytics solutions. Collaborate with stakeholders to enhance data quality and support enterprise-level data...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Lead core banking system conversions for credit unions, ensuring seamless project delivery through effective stakeholder communication, data migration, and interface integration, while managing risks...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $135K *

Drive operational excellence by leveraging data analysis and Lean Six Sigma methodologies. Lead initiatives that enhance performance across functions, mentor teams, and align improvements with strateg...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$190K - $220K *

Partner with us to tackle complex engineering challenges, leveraging deep expertise in TypeScript, Postgres, and AWS. Collaborate closely with our VP of Engineering to innovate and deliver impactful p...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $100K *

Join a team that's redefining telecommunications by providing expert Tier 3 and 4 support, engineering, and deployment for cutting-edge voice solutions. Collaborate with peers and mentor junior member...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Transportation

$90K - $130K *

Join a team that's driving large-scale infrastructure projects. As a Project Manager, you'll lead initiatives from kickoff to closeout, ensuring alignment with program objectives and stakeholder expec...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$79K - $88K *

Accelerate project success by managing customer implementations from start to finish. Drive solution definition, resource allocation, and risk management while ensuring client satisfaction and team co...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$73K - $102K *

Architect and deliver LLM-powered applications, overseeing the entire development lifecycle from design to deployment. Collaborate with cross-functional teams to integrate AI systems and ensure high-q...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$67K - $111K *

Join us to drive software solutions by collaborating on design, coding, and testing. Contribute to quality assurance and user training while enhancing system reliability through proactive problem-solv...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $138K *

Elevate customer experience by leading technical engagement during pre-sales. Utilize deep knowledge to craft solutions, mentor peers, and ensure seamless transitions, while remaining adaptable in a f...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$104K - $166K *

Shape the future of data integration by leading the development of robust data pipelines and enhancing fraud detection systems. Collaborate with cross-functional teams to ensure seamless data flow and...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $130K *

Lead the enhancement of security measures for cloud-based healthcare solutions, focusing on vulnerability management, incident response, and compliance. Collaborate with cross-functional teams to ensu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $210K *

Lead the design and implementation of cross-platform solutions in AWS GovCloud, focusing on Informatica architecture, security, and CI/CD practices. Collaborate with multidisciplinary teams to ensure...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$142K - $161K *

Join us to ensure the highest quality standards for our FDA-cleared AI clinical platform. Collaborate across teams to drive software design quality, manage regulatory compliance, and enhance post-mark...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Champion the deployment of cutting-edge AI systems in diverse environments. Collaborate with teams to ensure seamless installation and operation of hardware and software, while providing exceptional c...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$145K - $157K *

Transform space operations by leveraging Kubernetes to deliver resilient solutions. Collaborate within an Agile framework to enhance software deployment, ensuring optimal performance and security for...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$95K - $149K *

Lead the charge in delivering complex product development projects by managing cross-functional teams, ensuring customer satisfaction, and driving operational excellence from initiation to delivery in...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$200K - $500K *

Deliver exceptional user experiences by blending research, design, and collaboration. Drive UX/UI initiatives for web and mobile platforms, ensuring usability and accessibility while aligning with bus...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.