Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$145K - $200K *

Transform your career by developing robust SDKs that empower customers globally. Collaborate with cross-functional teams to enhance performance and resiliency while contributing to open-source project...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$179K - $248K *

Lead the charge in operationalizing strategy and driving cross-division initiatives. Collaborate with senior stakeholders to enhance efficiency and client satisfaction in a fast-paced corporate travel...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$107K - $195K *

Lead the charge in developing advanced platforms that automate operations and enhance AI-driven interactions. This hands-on role combines technical leadership with coding, mentoring, and ensuring comp...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$148K - $190K *

Join us to lead user experience design on our innovative learning platform. You'll own the design end-to-end, establishing a design system, shaping navigation, and enhancing the student experience thr...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$172K - $188K *

Lead the charge in clinical data programming by designing, building, and maintaining data collection systems. Collaborate with teams to ensure data integrity and support clinical development through a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Unlock potential by designing and building robust data pipelines for healthcare transactions. Collaborate with partners to ensure seamless integration and reliability of data systems, enhancing operat...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $152K *

Elevate your career by leading consulting engagements in utility-scale power generation, focusing on renewable energy and battery storage. Collaborate with clients and stakeholders to deliver innovati...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Unlock potential by designing and managing cloud systems, collaborating with teams to implement scalable architectures, and ensuring security and performance across platforms. This role requires indep...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the charge in delivering innovative remedial systems design solutions. Collaborate with multidisciplinary teams, providing technical leadership and strategic direction for diverse environmental p...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Technical Services

$145K - $190K *

Lead the design and evolution of scalable data architecture, providing technical leadership across teams to deliver reliable, secure, and cost-effective data solutions while shaping emerging capabilit...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$242K - $275K *

Lead and elevate the Database Platform team, driving data architecture, reliability, and team culture for scalable data solutions. Collaborate cross-functionally to ensure data integrity and operation...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Lead quantitative user research across product lines, shaping strategy and answering critical questions with data-driven insights. Collaborate with teams to prioritize research that mitigates risk and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Lead the charge in cloud security engineering by managing a team of experts to design and implement robust security controls across AWS, Azure, and GCP, ensuring compliance and operational excellence...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$105K - $126K *

Lead and optimize subcontract management by negotiating agreements, ensuring compliance, and collaborating with stakeholders to drive successful federal contracting outcomes while mentoring junior sta...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $160K *

Transform program execution by coordinating large-scale data center initiatives, ensuring alignment across stakeholders, managing risks, and driving milestones to successful completion while fostering...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$90K - $110K *

Deliver impactful data insights by transforming complex datasets into actionable analytics. Collaborate with stakeholders to enhance decision-making and support advanced analytics initiatives within a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Transform endpoint security by implementing innovative solutions and collaborating with IT teams to enhance protection against cyber threats. Contribute to the development and maintenance of robust se...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$195K - $225K *

Drive security innovation by shaping technical strategies and frameworks that protect sensitive data and systems. Collaborate across teams to embed security practices, mentor engineers, and ensure com...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$73K - $102K *

Grow as a quality consultant driving non-conformance management and continuous improvement initiatives in aerospace manufacturing. Collaborate with cross-functional teams to enhance product quality an...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$88K - $147K *

Oversee project financial performance and analytics, ensuring effective management across complex contracts. Collaborate with teams to enhance processes and deliver actionable insights, driving operat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$244K - $279K *

Lead innovation as a key technical expert, driving cloud-based banking solutions while collaborating on scalable, high-volume payment systems in a dynamic engineering environment. Shape the future of...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$111K - $150K *

Drive innovation in renewable energy by conducting power system studies, utilizing advanced software tools, and collaborating with diverse teams to enhance efficiency and support sustainable solutions...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$94K - $266K *

Join a team that's shaping the future of AI solutions by developing scalable, innovative applications within the Salesforce ecosystem. Collaborate with clients to deliver strategic initiatives and exp...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$200K - $295K *

Lead innovative data analysis initiatives to develop contextual insights from autonomous vehicle data, driving meaningful improvements in safety and performance across mobility services...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Transportation

$90K - $152K *

Advance your career by leading mainframe capacity planning initiatives, optimizing performance, and driving automation solutions. Collaborate with teams to enhance operational efficiency and mentor ju...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.