Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$120K - $145K *

Transform your career by owning AWS cloud operations, enhancing reliability, performance, and cost efficiency. Collaborate with cross-functional teams to ensure seamless service delivery and operation...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$72K - $120K *

Unlock your potential as a key contributor in financial systems, enhancing Workday Financials and driving process efficiency. Collaborate with stakeholders to deliver scalable solutions and support cr...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$161K - $190K *

Join us to define and evolve the architecture of a cutting-edge digital platform, guiding engineering decisions and establishing shared services for scalable, secure, and reliable solutions that empow...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Join a team that's shaping the future of interconnect technology by designing innovative connector solutions. Leverage your engineering expertise to collaborate globally and meet the demands of leadin...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $137K *

Empower customers as a Senior Technical Support Engineer, solving complex technical issues with modern tools while enhancing user experience, collaborating with engineering, and shaping innovative sup...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$280K - $330K *

Empower a dynamic engineering team by leading technical architecture, enhancing system reliability, and driving scalable solutions that support rapid growth in a fast-paced fintech environment. Foster...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$170K - $220K *

Shape the future of customer solutions by leading implementations and driving adoption of innovative technologies. Collaborate with teams to deliver tailored architectural designs that meet strategic...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$139K - $285K *

Drive the analytics engineering team to create AI-ready data solutions, ensuring trusted access to data across the organization. Lead strategic initiatives, build self-service capabilities, and foster...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$160K - $180K *

Join a team that's dedicated to delivering seamless technical solutions for clients. You'll scope, implement, and maintain risk screening and data integration workflows, ensuring optimal performance a...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $125K *

Drive the deployment of healthcare technology across multiple VA facilities, coordinating projects and ensuring readiness. Collaborate with diverse teams to manage timelines, resolve issues, and deliv...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $266K *

Champion MuleSoft implementations by developing clean code and guiding teams. Leverage expertise in Salesforce and API management to deliver enterprise-grade solutions while mentoring junior developer...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$208K - $312K *

Drive IAM strategies across corporate and production environments, defining architecture, standards, and automating processes. Lead initiatives that enhance security, simplify access, and empower team...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$84K - $148K *

Lead the charge in optimizing mainframe database environments, ensuring seamless upgrades, administration, and performance tuning. Collaborate with vendors and support clients with 24x7 on-call assist...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$204K - $290K *

Manage the Resilience Engineering team to enhance system reliability through production load testing and chaos engineering while fostering a proactive safety culture across engineering practices...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$250K - $500K *

Champion innovation by leading the migration to EKS, optimizing cloud infrastructure, and enhancing Kubernetes operations. Drive automation and CI/CD processes while ensuring high availability and per...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$112K - $135K *

Elevate your career by designing and implementing cloud infrastructure solutions in Azure. Collaborate with teams to automate deployments, optimize CI/CD pipelines, and leverage AI tools for enhanced...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$155K - $180K *

Drive successful delivery of complex, multi-year programs in a dynamic environment. Collaborate with cross-functional teams to manage scope, budget, and timelines while ensuring client satisfaction an...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$200K - $250K *

Optimize your career as a full-stack software engineer, collaborating with agile teams to enhance high-transaction e-commerce applications. Drive quality, mentor peers, and innovate solutions that ele...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Design and optimize evaluation systems for AI agents, enhancing performance and quality through innovative metrics and benchmarks. Collaborate with cross-functional teams to ensure agents meet user ne...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Elevate the quality assurance landscape by building robust test automation frameworks, driving efficient testing practices, and partnering with cross-functional teams to ensure excellence in software...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $160K *

Optimize patient-facing and internal tools by delivering seamless integrations and AI-driven features. Take ownership of end-to-end development in a fast-paced telehealth environment focused on men's...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $111K *

Lead cross-functional teams to design and implement resilient infrastructure solutions. Collaborate with diverse stakeholders to ensure timely delivery of high-quality systems, leveraging automation a...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$110K - $125K *

Join a team that's redefining web development by building innovative applications. Leverage your full-stack expertise in JavaScript and Python while managing cloud infrastructure and data pipelines to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Elevate project delivery by managing integrated schedules for data center builds, ensuring timely execution across teams and partners. Drive risk management and governance while building scalable proc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$99K - $120K *

Join our innovative team to architect and deliver cutting-edge IoT systems for special projects. You'll drive initiatives from concept to field pilot, integrating advanced technologies in a dynamic, c...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.