Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$120K - $125K *

Transform data analytics initiatives by leading multiple projects, engaging stakeholders, and driving solutions from inception to delivery. Collaborate with technical teams to ensure alignment with mi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$250K - $300K *

Shape the future of AI-driven platforms by designing scalable applications and intelligent workflows. Lead initiatives that enhance operational efficiency and enable real-time insights, while mentorin...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$105K - $234K *

Lead the design and delivery of complex platform capabilities, enhancing reliability and security while mentoring engineers. Collaborate across teams to drive technical excellence and implement AI-ass...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$202K - $253K *

Elevate your leadership as you drive engineering excellence, overseeing multiple squads from prototype to production. Shape the roadmap, empower teams, and ensure quality delivery while staying techni...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $173K *

Transform data acquisition processes by leading the development of high-performance ingestion pipelines. Collaborate across teams to ensure data quality, reliability, and security while shaping the fu...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Empower your career as a Platform Engineer, driving innovation in system architecture and cloud technologies. Collaborate with cross-functional teams to enhance platform efficiency and guide junior en...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $155K *

Drive innovation by developing AI-driven software solutions that enhance secure application delivery. Collaborate with cross-functional teams to tackle complex challenges and shape the future of softw...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $135K *

Drive impactful mortgage analysis through collaboration with cross-functional teams. Leverage industry expertise to optimize integrations, enhance product functionality, and document processes for tra...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$112K - $126K *

Elevate AI capabilities by building and maintaining governed solutions. Collaborate cross-functionally to translate business needs into technical designs, ensuring ethical AI use and robust integratio...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$140K - $187K *

Innovate the future of AI security by designing and implementing robust defenses against adversarial threats, ensuring the integrity of AI systems while fostering innovation and collaboration across c...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$118K - $134K *

Unlock potential by driving innovative software solutions in a collaborative, fast-paced environment. Contribute to modernizing business applications while working closely with IT and business teams t...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$143K - $196K *

Champion innovative solutions in healthcare coding by leading cross-functional teams, optimizing product strategies, and enhancing customer experiences through data-driven insights and agile methodolo...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $246K *

Champion innovative IAM solutions by designing secure software and optimizing SaaS services. Collaborate across teams to embed security practices, conduct threat modeling, and enhance monitoring syste...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $160K *

Shape the future of global merchandising technology by leading engineering efforts, driving modernization, and ensuring high-quality delivery across diverse platforms. Collaborate with teams to implem...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Join a team that's at the forefront of machine learning and search innovation. Collaborate with cross-functional teams to develop scalable ML systems that enhance user experiences and drive impactful...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$173K - $255K *

Champion the future of data infrastructure by leading a team to deliver scalable, reliable solutions for data access and processing, ensuring high availability and supporting critical business operati...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$193K - $309K *

Join a dynamic team to enhance cloud security capabilities, leading hands-on initiatives and shaping strategic direction. Collaborate across engineering teams to secure AWS environments and mentor pee...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$149K - $198K *

Elevate user experience by architecting and implementing visualization solutions. Collaborate across teams to enhance automated testing and drive best practices in performance and scalability, deliver...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Transportation

$122K - $205K *

Empower the public sector by modernizing software development with AI-driven solutions. Drive strategic initiatives, cultivate executive relationships, and navigate procurement processes to deliver im...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$142K - $186K *

Pioneer a data-driven culture by designing scalable ELT pipelines and analytics models. Collaborate across teams to ensure product data integrity and empower stakeholders with self-service insights, d...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $160K *

Elevate cloud security and reliability by leading DevOps practices across teams. You'll optimize AWS and GCP environments, enhance CI/CD pipelines, and ensure cost-effective engineering tools, driving...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$220K - $270K *

Unlock potential by guiding application security strategies across diverse product landscapes. In this senior technical role, you'll influence architecture, mentor teams, and enhance security processe...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Enterprise Technology

$139K - $235K *

Transform customer infrastructure management by owning the product vision and roadmap for a key control plane. Collaborate with engineering to enhance user experience and operational efficiency, drivi...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform product operations by enhancing collaboration across teams and streamlining the launch processes. Utilize data-driven insights and AI to identify bottlenecks and drive efficiency, ensuring s...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$130K - $160K *

Unlock potential by leading mobile app development, shaping user experiences, and driving technical direction in a fast-paced environment. Collaborate with cross-functional teams to deliver intuitive...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.