Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$110K - $130K *

Partner with us to bridge technical solutions and customer needs in a dynamic, cross-functional role. Utilize your expertise to drive adoption of AI agents, influencing product roadmaps and enhancing...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $144K *

Lead the charge in designing and implementing advanced building automation systems for critical infrastructure projects, ensuring seamless integration and optimal performance while managing teams and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$125K - $155K *

Join our dynamic team as a Senior Solutions Engineer, where you'll leverage your technical expertise to drive pre-sales activities, engage with clients, and deliver tailored solutions that enhance bus...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $160K *

Elevate your career by supporting senior leaders in a dynamic tech environment. Manage complex calendars, coordinate travel, and streamline processes to enhance productivity and drive success across g...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Contribute to innovative data solutions by designing and maintaining an enterprise data warehouse, building robust ETL pipelines, and delivering impactful analytics that drive key business decisions...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$84K - $87K *

Join us as a Data Operations Engineer, where you'll develop and manage data systems for healthcare claims processing. Collaborate with teams to ensure data accuracy and optimize ETL/ELT pipelines whil...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Transform the future of mobile broadcasting by leading technical operations, ensuring show readiness, and delivering exceptional live production experiences while mentoring teams and managing client r...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$70K - $117K *

Unlock potential by leveraging your expertise in structural engineering to ensure the integrity and safety of marine vessels. Collaborate with a dynamic team to support critical naval operations and e...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Innovate noise control solutions for large-scale AI data centers. Lead acoustic studies, model sound propagation, and recommend effective mitigations while collaborating across engineering teams to en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in automating and scaling network infrastructure across diverse global datacenters, enhancing performance and security while collaborating with engineering teams to implement robust so...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Join a team that's shaping the future of AI solutions by deploying and integrating cutting-edge technologies. Collaborate with customers and engineers to enhance system performance and drive innovatio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate your career by implementing and supporting AWS cloud solutions in a dynamic environment. Collaborate with experts to optimize performance and ensure secure, scalable infrastructure for federal...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$151K - $178K *

Shape the future of credit decisioning by leading a team focused on automating underwriting processes, enhancing portfolio analytics, and driving policy governance in a fast-paced fintech environment...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$145K - $185K *

Lead enterprise-level architectural initiatives to enhance endpoint technologies, guiding modernization efforts and integrating emerging solutions across multiple divisions while ensuring security and...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$120K - $130K *

Join a dynamic team to design and optimize scalable data solutions that enhance healthcare technology platforms. Collaborate with cross-functional teams to ensure data integrity and drive informed dec...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$68K - $143K *

Join us to enhance business processes through analysis and reengineering, collaborating with stakeholders to ensure effective solutions and implementation. Drive efficiency and innovation in transport...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Lead the charge in designing a cutting-edge platform for modern data centers, integrating AI and cloud technologies. Collaborate with cross-functional teams to build a robust, scalable architecture th...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Shape the future of embedded systems engineering by leading a high-performance team, defining technical roadmaps, and integrating AI-driven workflows to deliver innovative, reliable solutions across d...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Optimize network infrastructure within the DHMS program, ensuring reliability, performance, and security. Collaborate with IT teams to develop policies, troubleshoot issues, and maintain compliance wi...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Lead advanced troubleshooting and repair of medical equipment, ensuring customer satisfaction through service excellence. Collaborate with teams, mentor junior engineers, and drive initiatives to enha...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$137K - $182K *

Architect and drive AI-powered applications for drug development, focusing on protocol generation and clinical trials. Lead technical direction, mentor engineers, and ensure compliance while fostering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$123K - $218K *

Champion user-centered information experiences by leading a distributed team to create impactful technical documentation and content strategies that enhance customer and developer engagement across mu...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $160K *

Unlock your potential as a Senior Full Stack Software Engineer, leading impactful projects and shaping technology solutions. Collaborate across web applications, backend services, and cloud infrastruc...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Transform the future of secure, reliable applications and cloud services by leveraging modern software engineering and DevOps practices to enhance delivery, security, and developer experience in a col...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$154K - $185K *

Join our dynamic team to develop next-gen storage solutions, enhancing Grafana's App Platform. Collaborate on innovative features, drive projects from ideation to operations, and contribute to an open...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.