Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$74K - $111K *

Join a team that's dedicated to delivering exceptional service through timely maintenance and repairs of medical equipment, ensuring optimal healthcare delivery while enhancing customer satisfaction a...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$105K - $157K *

Deliver exceptional service as a Field Engineer, resolving advanced technical issues and enhancing customer satisfaction. Collaborate with teams to drive service excellence and support business growth...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$150K - $180K *

Join a transformative team as an Engineering Manager to lead engineering initiatives, inspire innovation, and drive technical excellence in revolutionizing healthcare technology while fostering profes...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Transform client businesses by leading AI strategy and implementation. Drive impactful consulting engagements, build trusted relationships, and leverage emerging technologies to deliver measurable out...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Lead the development and operation of next-gen GraphQL infrastructure, ensuring performance, security, and reliability while mentoring teams and collaborating cross-functionally to deliver outstanding...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $145K *

Join a dynamic team to design and implement cloud security solutions, enhancing information security and compliance while mitigating cyber threats across the organization. Drive innovation and improve...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$63K - $111K *

Join a team that's dedicated to producing high-quality technical documentation. Collaborate with engineers and project teams to create clear, accurate reports while ensuring compliance with standards...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$135K - $216K *

Lead the charge in managing a software engineering team, driving the design and delivery of secure satellite ground communication services while fostering best practices and ensuring alignment with mi...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$160K - $180K *

Unlock potential by providing hands-on technical leadership across the full stack. Collaborate with cross-functional teams to design scalable solutions, enhance product experiences, and drive impactfu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Reimagine cloud infrastructure as you build and operate scalable systems that empower product teams. Ensure reliability and speed in a dynamic environment, supporting enterprise-scale solutions for Fo...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Lead a strategic portfolio within a large-scale transformation, ensuring delivery excellence across multiple programs and managed services while driving innovation through AI-native practices and oper...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Information Technology

$153K - $210K *

Strategize and enhance data integrity across extensive systems, ensuring all operational data is accurate and reliable for key clinical and financial workflows while enabling self-serve analytics for...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $135K *

Unlock excellence in PCB design and manufacturing by leading DFM initiatives, developing complex multilayer layouts, and shaping best practices across engineering teams to enhance product performance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$180K - $235K *

Lead the charge in developing robust backend applications, driving complex projects from design to launch. Collaborate across teams, mentor junior engineers, and tackle architectural challenges to enh...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $217K *

Lead the charge in designing innovative, scalable software solutions that transform complex processes into actionable insights, partnering with diverse teams to deliver high-performance applications f...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$101K - $135K *

Join a team that's shaping the future of healthcare technology by designing and enhancing our build and delivery infrastructure. Collaborate with architects and developers to implement best practices...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by engaging customers to develop tailored solutions using open-source technologies and cloud-native architecture. Drive success through collaboration and innovation, bridging engineer...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$186K - $267K *

Take ownership of technical leadership within a dynamic engineering team, enhancing software solutions for workload security. Focus on scalability, performance, security, and reliability in complex en...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$160K - $180K *

Lead the charge in driving agile execution across product and engineering teams, managing digital product launches and enhancing client value through innovative solutions. Collaborate cross-functional...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$173K - $255K *

Drive innovation in AI systems by designing and building scalable backend solutions, ensuring security and governance while enhancing developer productivity and operational health across diverse workl...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Transform application deployment by collaborating with teams to streamline processes, enhance automation, and ensure high-quality releases across environments while mentoring junior members and drivin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$173K - $233K *

Empower innovation by leading the design and development of scalable, high-availability systems. Collaborate across teams to enhance our card loan platform, ensuring robust performance and driving imp...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $150K *

Join a dynamic team to design and develop innovative mobile solutions across Android and iOS. Take ownership of projects, collaborate with peers, and contribute to the broader tech stack while enhanci...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$125K - $150K *

Unlock your potential as you empower deployment and automation solutions in high-security environments. Leverage your expertise in DevOps and platform engineering to ensure robust operations across fe...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Optimize product quality by leading engineering projects, ensuring compliance with ISO and QSR regulations, and working collaboratively across departments to enhance performance and maintain high stan...

1 month ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.