Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$95K - $115K *

Lead the charge in building and maintaining CI/CD pipelines while administering Linux/Windows servers. Collaborate on configuration management and mentor team members to enhance DevOps practices in a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Elevate your career by driving data engineering excellence in Palantir Foundry, transforming legacy systems into robust pipelines and applications while collaborating with cross-functional teams to de...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$99K - $167K *

Develop and maintain robust data pipelines using SparkSQL and Pyspark, ensuring high-quality data for analytics. Collaborate with cross-functional teams to enhance data analysis efficiency and support...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Lead the charge in building AI-powered engineering systems that enhance developer workflows, ensuring reliability and ease of adoption for engineers. Collaborate with teams to create innovative soluti...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Join our team to enhance security and automation in delivery pipelines, driving consistent deployments and compliance through modern DevSecOps practices alongside skilled professionals...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Transform product security by leading strategy, conducting threat modeling, and collaborating across teams to ensure secure design and compliance. Drive innovation in security practices while mentorin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$89K - $125K *

Partner with us to integrate new firms into our IT environment, managing Microsoft 365 migrations and Active Directory consolidations while collaborating with cross-functional teams to ensure seamless...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $175K *

Engineer your career with a Senior Software Safety Engineer role focused on developing safety-critical autonomous systems. Collaborate with a multi-disciplinary team to enhance software safety process...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$115K - $165K *

Join a team that's redefining the shopping experience by enhancing search capabilities. Collaborate with stakeholders to balance speed and quality, ensuring robust backend systems while fostering comm...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $160K *

Drive the development of scalable software solutions, enhancing computer vision and LLM systems. Collaborate with cross-functional teams to deliver impactful features while ensuring reliability and ef...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Unlock the potential of NetBox Delivery by leading software design, enhancing production reliability, and mentoring engineers. Shape the technical direction and ensure seamless deployment on Cloud and...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$190K - $225K *

Optimize system performance by building scalable, robust services. Collaborate across teams to design public APIs, ensuring high-quality integration for retailers. Mentor others and evolve solutions t...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$146K - $206K *

Reimagine data infrastructure by designing and scaling backend systems, collaborating across teams, and driving innovative use cases. Leverage technologies like AWS, Kafka, and Flink to enhance data e...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $175K *

Lead innovative cloud solutions by architecting and managing robust platforms. Collaborate with a dynamic team to tackle complex challenges in AWS and Azure, enhancing your skills while driving impact...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Join a dynamic team to design and build a robust data platform that enhances product performance and supports AI initiatives, ensuring data integrity and accessibility for internal and customer-facing...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Empower our team to build innovative security and governance solutions, shaping access management for both human and agent users. Lead a small, dynamic group as we define architectural foundations and...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by joining a dynamic Global SRE team focused on enhancing software reliability and observability. Collaborate with teams to implement best practices and innovative solutions, ensuring...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Empower the backend development of our co-branded credit card product, creating secure services and APIs while ensuring compliance and performance. Collaborate across teams to drive innovation and men...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Enterprise Technology

$242K - $275K *

Lead the charge in developing and deploying robust containerized software, manage CI/CD workflows, and grow a cohesive engineering team to enhance customer security operations and software delivery ac...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$78K - $98K *

Shape the future of AEC workflows by leading product ownership and Agile delivery for an Engineering Tools team. Collaborate with cross-functional stakeholders to prioritize needs, validate outcomes...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Elevate our search capabilities by architecting high-scale solutions, leading multi-quarter transformations, and ensuring operational excellence across a global cloud infrastructure while mentoring em...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$152K - $259K *

Transform security analysis by leading the development of a static analysis engine. Shape technical direction, mentor engineers, and drive initiatives that enhance code security and performance across...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$217K - $303K *

Lead the charge in evolving a cohesive design system for Android, enhancing UI architecture and performance. Collaborate with cross-functional teams to build reusable components and improve accessibil...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$225K - $265K *

Drive the development of seamless integrations for security platforms, leading a team to deliver high-quality, reliable products that enhance customer security stacks and ensure compatibility with evo...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $205K *

Join a dynamic team to lead AI agent deployments in healthcare. Leverage your software engineering expertise and client-facing skills to drive technical delivery, influence product development, and en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.