Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$93K - $140K *

Deliver impactful SampleManager LIMS solutions by configuring, implementing, and integrating in diverse laboratory settings. Leverage technical expertise to enhance workflows and drive successful proj...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $240K *

Shape the future of robotics by leading cross-functional technical projects, ensuring timely execution and delivery while collaborating globally. Your strategic oversight will drive innovations in UAV...

Reposted yesterday

  •   8 - 10 years exp.  •   Consumer Technology

$170K - $210K *

Empower Federal agencies by architecting and delivering AI-assisted software solutions. Responsible for client engagement, technology integration, and ensuring that production-ready solutions meet ope...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$130K - $155K *

Join a team that designs and deploys lab environments for Cloud Security Posture Management using advanced OpenStack expertise. Contribute to testing and validating API-based security tools in multi-t...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $300K *

Transform complex mechanical subsystems for robotic manipulation and data collection. Collaborate with cross-functional teams to design, prototype, and validate innovative solutions, ensuring reliabil...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Transform supplier quality by ensuring compliance with standards and driving improvements. Collaborate with suppliers to enhance processes, conduct audits, and resolve quality issues, while supporting...

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$122K - $183K *

Champion automation excellence by leading initiatives that enhance manufacturing performance and drive innovation. Collaborate with cross-functional teams to implement cutting-edge technologies and op...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$113K - $163K *

Transform your career by driving engineering excellence and innovation in photolithography equipment. Lead improvement initiatives and mentor engineers while ensuring optimal performance and reliabili...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$140K - $234K *

Unlock your potential as you develop and support core products, collaborating with teams to enhance features and drive innovation in cloud solutions using C# and modern technologies...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$147K - $210K *

Transform AI development by engineering cutting-edge software solutions that enhance human-AI interaction. Collaborate with a dynamic team on innovative projects that push boundaries in machine learni...

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$156K - $215K *

Unlock the potential of cutting-edge technology by developing robust security components for our GenAI platform, ensuring real-time threat protection and a seamless customer experience through innovat...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$57K - $108K *

Join a team that's shaping the future of missile defense technologies. As a Systems Engineer I, you'll plan and execute complex integration and verification tests, contributing to innovative solutions...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $120K *

Lead the charge in enhancing security for a complex federal platform, safeguarding cloud infrastructure and sensitive data. Collaborate within an Agile team to design, implement, and automate robust s...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $135K *

Join a team that's pioneering innovative software solutions to enhance environmental sustainability through robust full-stack application development for Federal clients, ensuring security, compliance...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $114K *

Transform data systems and pipelines to empower AI/ML applications, collaborating with technical teams to enhance mission-critical operations and ensure data quality across the Navy IT ecosystem...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Champion the successful delivery of customer projects through all phases, ensuring alignment with business goals by coordinating teams and resources while managing risks and transacting key communicat...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $202K *

Transform financial systems by architecting high-scale, low-latency distributed solutions. Lead cross-team initiatives, enforce engineering standards, and drive innovative technology adoption while me...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $202K *

Lead the charge in architecting robust, scalable backend systems in a cloud native environment. Collaborate across domains to ensure high availability, data consistency, and regulatory compliance for...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $140K *

Lead the charge in designing and executing rail projects, ensuring compliance and quality. Collaborate with multidisciplinary teams and strengthen client relationships while managing project delivery...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$156K - $170K *

Make your mark at the forefront of Cybersecurity by developing advanced embedded software solutions. Collaborate with cross-functional teams to enhance mission-critical devices, ensuring robust perfor...

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$67K - $92K *

Join a team that's dedicated to ensuring software quality through automated testing. Collaborate with developers, execute test cases, and leverage AI tools to enhance testing processes while participa...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$94K - $291K *

Design and engineer innovative cloud-native AI solutions, embedding with clients to build agentic systems. Lead adoption globally while enhancing workflows across diverse enterprise environments throu...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$250K - $362K *

Drive innovation and develop cutting-edge technology solutions that impact a global market. Collaborate with teams to shape product strategies, mentor experts, and influence industry standards while e...

RemoteRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$269K - $307K *

Shape the future of AI by leading cross-functional teams to design, develop, and implement innovative AI-powered solutions that transform customer experiences and improve operational efficiencies in t...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$132K - $165K *

Lead the charge in building cutting-edge data lakes and warehouses, guiding cross-functional teams to optimize data strategies, ensuring robust architecture, and mentoring junior engineers in a dynami...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.