Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Associate, Strategy & Partnerships
$78K - $145K *
Drive strategic growth by analyzing business opportunities and collaborating with C-suite executives. Manage cross-functional projects in a high-growth healthcare environment, ensuring confidentiality...
5 days ago
Neurointensive ICU Advanced Practice Provider (PA/NP) - UNC Faculty Physicians
$95K - $115K *
Unlock potential by delivering high-quality, patient-centered care as part of an interdisciplinary team. Collaborate with physicians to develop treatment plans, educate patients, and lead initiatives...
2 days ago
$83K - $108K *
Elevate patient care by evaluating and treating swallowing and communication disorders. Collaborate with a dedicated team to develop personalized therapy programs, ensuring each patient receives focus...
2 weeks ago
$83K - $114K *
Deliver individualized speech therapy services to patients with swallowing and communication disorders, collaborating with a multidisciplinary team to enhance patient care and outcomes through evidenc...
2 weeks ago
$81K - $97K *
Join a team that's dedicated to enhancing lives by assessing and treating patients with swallowing disorders and communication challenges through personalized therapy and collaboration with medical te...
3 weeks ago
Solutions and Services Architect
$85K - $118K *
Innovate the pharmacy landscape by architecting comprehensive TPA solutions, transforming complex requirements into streamlined operations, and enhancing client outcomes through strategic PBM partners...
3 weeks ago
$250K - $286K *
Shape the future of sales by leading a dynamic team to drive new business, refine strategies, and enhance customer experiences in a fast-paced SaaS environment, while mentoring leaders and achieving a...
2 weeks ago
Architecture Senior Advisor- Hybrid
$110K - $130K *
Contribute to the architectural foundation for innovative applications, guiding teams in technical exploration, solution design, and best practices to enhance delivery capabilities and support enterpr...
1 week ago
$80K - $95K *
Join our team as a Geophysicist, where you'll tackle complex subsurface investigations, lead project phases, mentor junior staff, and contribute to vital infrastructure projects. Bring your expertise...
3 weeks ago
$80K - $95K *
Explore transformative geophysical technologies to guide infrastructure and environmental projects. Lead teams in surveying, data analysis, and proposal development, ensuring quality and safety throug...
3 weeks ago
$80K - $95K *
Engineer cutting-edge geophysical investigations, analyzing subsurface conditions for essential infrastructure projects while mentoring junior team members and ensuring project quality...
3 weeks ago
Technical Architect Contractor
$110K - $130K *
Unlock potential by leveraging your Salesforce expertise to design, build, and review secure, scalable solutions. Collaborate with clients and teams to ensure seamless integrations and effective deliv...
3 days ago
Medical Director - Critical Care
$300K - $309K *
Transform patient care by leading medical strategy and clinical innovation. As a vital member of the team, you'll guide product development and trial execution while engaging with key stakeholders to...
Reposted 3 weeks ago
Assoc Dir, Neuro Thought Leader Liaison (West region)
$190K - $225K *
Empower commercial strategies by building relationships with key thought leaders in rare neurological diseases, capturing insights to inform brand development and launch planning, and ensuring impactf...
3 weeks ago
Solutions Architect (Contract)
$156K - $187K *
Transform the data landscape by designing and implementing robust integration solutions. Collaborate with cross-functional teams to enhance analytics infrastructure, ensuring seamless data flow and go...
2 weeks ago
$89K - $110K *
Shape the future of students by providing essential speech-language therapy services in a supportive school environment. Collaborate with educators and families to enhance communication skills and fos...
2 days ago
Senior Medical Physicist (Truckee, CA)
$190K - $262K *
Join us to ensure high-quality radiation therapy through expert oversight, compliance, and innovative practices. Collaborate with a dedicated team to enhance patient safety and deliver exceptional car...
1 week ago
Manager Clinical Registry Operations - Trauma / Orthopedic
$99K - $148K *
Transform your career with a leadership role overseeing clinical data management, ensuring compliance, and driving quality improvement initiatives across the enterprise. Collaborate with diverse teams...
3 days ago
$180K - $220K *
Elevate patient care by joining a dynamic team of Family Medicine Physicians. Enjoy autonomy while collaborating with dietitians and therapists in a supportive environment, enhancing community health...
1 week ago
Nurse Practitioner Palliative Care
$90K - $110K *
Join a team that's dedicated to enhancing patient quality of life through advanced palliative care. Collaborate with healthcare professionals to provide compassionate support and individualized treatm...
1 week ago
$80K - $95K *
Champion excellence in rehabilitative care by leading clinical programs, enhancing patient lives, and fostering team collaboration to ensure optimal therapeutic outcomes in a dynamic facility environm...
3 weeks ago
Executive Director, Translational Medicine & Pediatric Planning
$246K - $332K *
Drive pediatric development strategy by integrating clinical insights and regulatory commitments across multiple therapeutic areas, ensuring effective execution from candidate transition to post-marke...
1 week ago
Ambulatory Care Pharmacist III
$110K - $130K *
Transform patient care by managing comprehensive medication strategies and fostering interdisciplinary collaboration to ensure effective health outcomes across the healthcare system...
Reposted 2 weeks ago
$100K - $120K *
Drive evidence-based healthcare improvements by leading evaluations and strategic analyses. Collaborate with multidisciplinary teams to enhance Military Health System outcomes through expert consultat...
2 weeks ago
Inpatient Palliative Care Advanced Practice Provider (PA/NP) - UNC Faculty Physicians
$95K - $115K *
Advance patient care by joining a dedicated team of Advanced Practice Providers, delivering holistic, evidence-based treatment to patients with serious illnesses in an inpatient setting, while collabo...
2 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.