Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$90K - $110K *
Drive excellence in estimating for telecommunications projects by leading the development of accurate, standardized cost libraries and estimates. Collaborate with cross-functional teams to ensure alig...
3 weeks ago
BIM Coordinator - Mi-Tech Services, Inc.
$95K - $115K *
Drive BIM/VDC execution on major construction projects, leading technical coordination and team management while enhancing long-term BIM capabilities and standards for complex initiatives...
1 week ago
Head of Reseller & Embedded Solutions
$210K - $263K *
Join a team that's redefining indirect sales strategies by building and scaling reseller and embedded partner programs. Drive significant revenue growth through strategic alliances and cross-functiona...
4 weeks ago
$120K - $132K *
Join a team that's dedicated to enhancing cybersecurity measures across cloud environments. Lead initiatives in data protection, compliance, and security awareness while mentoring peers and implementi...
2 weeks ago
Enterprise Sales Account Executive
$110K - $130K *
Unlock potential by leading strategic account management initiatives, driving customer satisfaction and revenue growth through effective relationship building and expansion strategies in a dynamic ent...
1 week ago
$144K - $188K *
Champion growth by leveraging your expertise in hybrid cloud solutions. Collaborate with sales teams to drive strategic initiatives, engage clients, and influence technology transformations that enhan...
3 weeks ago
$90K - $100K *
Join a team that's dedicated to optimizing payroll operations and compliance. This role supports payroll processing, reporting, and employee services, ensuring accuracy and scalability as the organiza...
5 days ago
AI Business Architect- Sales Operations
$156K - $234K *
Drive the evolution of Sales Operations into an AI-driven powerhouse by architecting innovative AI solutions, redesigning processes, and establishing best practices that enhance efficiency and perform...
Reposted 2 days ago
$80K - $95K *
Unlock your potential as a Structural Engineer, shaping modular construction from design to installation. Collaborate on diverse projects, ensuring safety and compliance while optimizing for efficienc...
3 weeks ago
Senior Cybersecurity Engineer - Security Service Edge
$97K - $161K *
Drive the design and implementation of security systems, enhancing existing solutions while solving complex challenges. Collaborate with cross-functional teams to ensure robust cybersecurity measures...
6 days ago
Control Systems Integrator III - Data Center
$95K - $115K *
Transform control systems for leading manufacturers by programming and troubleshooting PLC/HMI systems. Collaborate with clients to deliver innovative automation solutions that enhance manufacturing p...
1 week ago
$115K - $130K *
Advance financial operations by leading accounting processes, ensuring compliance, and fostering collaboration across teams. Drive efficiency and support strategic goals while managing a team and enha...
3 weeks ago
$135K - $160K *
Empower cross-functional collaboration by aligning technology with business priorities. Drive strategic initiatives, enhance cybersecurity compliance, and foster trusted relationships to optimize ente...
2 weeks ago
Advisory Solutions Architect - Missouri, Kansas or Oklahoma
$135K - $160K *
Engage with key stakeholders to deliver innovative solutions, providing pre-sales technical support and strategic technology plans that drive customer success and enhance business outcomes across dive...
1 week ago
$80K - $95K *
Elevate project execution by leading a team of Control Technicians, ensuring quality, timely completion, and effective communication across all stakeholders while providing technical support and mento...
3 weeks ago
Director, Analytics Engineering
$139K - $285K *
Drive the analytics engineering team to create AI-ready data solutions, ensuring trusted access to data across the organization. Lead strategic initiatives, build self-service capabilities, and foster...
2 weeks ago
Product Engineer- Endpoint Security
$90K - $153K *
Lead the enhancement and administration of enterprise endpoint security technologies, collaborating with cross-functional teams to optimize security processes and improve detection capabilities in a g...
2 weeks ago
Software Engineer 4 (Commercial Nuclear)
$113K - $178K *
Drive your career with a senior role focused on software development for control room simulators, collaborating with engineers to enhance plant models and ensure high-quality deliverables in a dynamic...
2 weeks ago
Software Engineer I - Top Secret
$88K - $154K *
Explore a dynamic role in cyber network operations, developing tools that support national security missions. Collaborate with a skilled team to enhance software capabilities and contribute to critica...
Today
$110K - $130K *
Drive growth by selling our innovative platform to financial institutions. Manage complex, multi-stakeholder sales cycles, guiding clients through their AI journey while exceeding annual quotas in a c...
1 week ago
$120K - $145K *
Empower our privacy program by automating processes, managing data subject requests, and ensuring compliance with GDPR and CCPA. You'll leverage technical skills to build scalable tools and systems, d...
3 weeks ago
Director, Field Intelligence Strategy & Governance
$185K - $344K *
Champion the evolution of field intelligence capabilities, driving strategic governance and analytics integration to enhance decision-making and execution support across the organization, ensuring ali...
1 week ago
$150K - $170K *
Unlock potential by leading hands-on security engineering efforts to modernize cybersecurity for a major federal agency. Collaborate with teams to remediate vulnerabilities and enhance cloud infrastru...
Today
$155K - $165K *
Develop a cutting-edge data ecosystem as a Senior Data Engineer, enhancing analytics, reporting, and machine learning. Collaborate with cross-functional teams to create efficient pipelines and accessi...
Reposted 1 week ago
Regional Chief of Cybersecurity
$112K - $172K *
Join a dynamic team as a Regional Chief of Cybersecurity, leading efforts to protect critical infrastructure. Collaborate with federal and state partners to develop strategies, conduct assessments, an...
Today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.