Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Facilities Tech Support - FENS Central
$86K - $138K *
Join our Telecom team to manage critical infrastructure, ensuring optimal performance of facilities and systems that support national air traffic management. Collaborate with experts to maintain uptim...
2 weeks ago
$110K - $120K *
Elevate pricing strategies by analyzing data, guiding deals, and enhancing profitability. Collaborate across teams to drive smarter pricing decisions and improve seller experiences, ensuring competiti...
1 week ago
Senior Director, NA Field Marketing
$160K - $190K *
Drive impactful multi-channel field marketing strategies that enhance demand generation, strengthen customer relationships, and optimize pipeline performance. Lead a high-performing team while collabo...
5 days ago
Electrical Engineer, Roadway Lighting Design, Midwest
$90K - $115K *
Drive innovative roadway lighting designs by conducting site surveys, developing plans, and providing technical support. Collaborate with project teams to ensure timely and budget-friendly execution w...
Reposted 5 days ago
Senior Compiler Engineer, Agentic Compiler Systems
$150K - $180K *
Transform the future of intelligent compiler technologies by designing and optimizing advanced systems that enhance developer productivity and system performance across software and hardware boundarie...
Yesterday
Senior Structural Engineer- Mission Critical
$95K - $115K *
Engage in the design and analysis of resilient structural systems for mission-critical facilities, ensuring robust solutions that meet stringent uptime requirements while collaborating closely with ar...
2 weeks ago
Electronic Exploitation Engineer
$95K - $115K *
Unlock potential by leveraging your expertise in electronic exploitation and RF engineering. Collaborate on innovative projects, conduct hands-on technical analysis, and contribute to intelligence mis...
1 week ago
Enterprise Account Executive - Eastern Market
$110K - $130K *
Champion sales excellence by driving enterprise public safety solutions and cultivating strategic relationships, ensuring client satisfaction and operational improvement across medium to large governm...
Reposted 3 weeks ago
$80K - $95K *
Join our dynamic Account Management Team to drive growth in the corporate occupier software market. Leverage your sales expertise to build lasting client relationships and uncover new opportunities wh...
1 week ago
Strategic Enterprise Account Executive
$350K *
Join a team that's redefining enterprise sales by driving strategic growth and building executive relationships with Fortune 1000 companies. You'll lead complex deals and shape our sales playbook in a...
2 weeks ago
$80K - $95K *
Champion strategic growth by managing major law enforcement accounts, driving revenue, and fostering relationships with key stakeholders. Collaborate cross-functionally to ensure successful outcomes a...
2 weeks ago
$135K - $160K *
Lead the charge in developing a cutting-edge AI product, managing a high-performing team of engineers while ensuring quality, reliability, and speed in delivery. Collaborate closely with Product and D...
2 weeks ago
$130K - $225K *
Join a team that's pioneering AI capabilities by designing, building, and deploying production-ready AI solutions. Collaborate with cross-functional teams to integrate advanced technologies into a sec...
3 days ago
Senior Project Controls Analyst
$160K *
Drive the future of project controls by providing expert EVM, cost, and schedule analysis for federal programs. Collaborate with cross-functional teams to enhance decision-making and ensure program co...
Yesterday
Senior Lead Marketing Data Platform Architect
$145K - $193K *
Transform the marketing data landscape by leading the architecture and evolution of a scalable data platform. Drive innovation in analytics, AI, and operational frameworks to enhance marketing strateg...
5 days ago
$90K - $110K *
Engage with clients to design and implement tailored Manhattan WMS solutions, ensuring optimal performance and support throughout the project lifecycle. Leverage your expertise to transform supply cha...
Reposted 3 days ago
Cybersecurity and Compliance Manager
$120K *
Take ownership of cybersecurity compliance initiatives, leading risk management and strategic advisory services to enhance client security programs and ensure adherence to regulatory standards across...
1 week ago
$97K - $126K *
Champion the development of high-performance real-time systems, ensuring reliability and maintainability. Collaborate with peers to implement solutions, enhance testing, and contribute to a culture of...
3 weeks ago
IT Security Engineer / Vulnerability Scanning Expert
$75K - $100K *
Advance IT security by managing vulnerability scanning tools and processes, ensuring the integrity of USDA systems. Collaborate across teams to implement solutions, troubleshoot issues, and maintain s...
6 days ago
Microsoft 365 Platform Engineer
$100K - $120K *
Transform the Microsoft 365 ecosystem by designing and implementing integrations, enhancing data flow, and ensuring compliance. Collaborate with cross-functional teams to modernize processes and drive...
3 weeks ago
Global Product Manager, Overhead Technologies
$114K - $151K *
Unlock potential by leading the HV overhead switchgear portfolio, driving product strategy, market development, and cross-functional collaboration to achieve profitable growth and enhance utility solu...
Reposted 1 week ago
Product Manager, National Center for Clinical Trials (NCCT)
$122K - $183K *
Transform how we operate by leading technology-driven initiatives that enhance business capabilities. Collaborate with cross-functional teams to define product strategies and drive measurable outcomes...
4 days ago
$120K - $144K *
Lead the charge in designing and implementing advanced building automation systems for critical infrastructure projects, ensuring seamless integration and optimal performance while managing teams and...
2 weeks ago
$170K - $200K *
Transform customer experiences by providing technical expertise and solutions. Collaborate with sales and engineering teams to deliver impactful product demonstrations and address technical challenges...
5 days ago
Sr. Application Security Engineer
$140K - $160K *
Join a team that's redefining application security by partnering with engineering leaders to influence secure design, conduct hands-on code reviews, and enhance security tooling, all while navigating...
4 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.