Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Network Architect Jobs in Missouri

Sort By: Relevance

$80K - $85K *

Join a dynamic team to support and enhance global IP network services, ensuring stability and availability for Financial Markets. Collaborate with engineers and customers to resolve complex issues and...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Partner with us to design and implement engaging front-end experiences for leading eCommerce brands. Leverage your skills in Figma and Shopify to create custom loyalty solutions, collaborating closely...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Unlock potential by leading pre-sales technical strategies that align solutions with client needs, driving revenue growth and retention through collaboration with sales teams and delivering tailored p...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$205K - $285K *

Grow your career with a dynamic team managing data center operations. Lead technical teams in hardware installation, configuration, and troubleshooting while driving safety initiatives and optimizing...

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Unlock your potential as you drive Oracle EPM Cloud Planning solutions, supporting clients in their transformations. Leverage your expertise to configure, implement, and coach while enhancing project...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$144K - $184K *

Transform strategic accounts by driving sales and fostering executive relationships. Leverage deep industry knowledge to identify opportunities and enhance client satisfaction, ensuring growth and ret...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$110K - $120K *

Join a team that's dedicated to optimizing sales solutions through technical expertise. Collaborate with cross-functional teams to develop proposals, evaluate technologies, and manage multiple project...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead the charge in crafting transformative data solutions by harnessing deep expertise in Salesforce Data 360 and enterprise architecture. Collaborate with clients to ensure scalable solutions that me...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $135K *

Shape the future of digital services by developing user-centric applications and enhancing software engineering practices. Collaborate with cross-functional teams to deliver impactful solutions for fe...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Empower your career by driving project delivery and managing Agile teams. Utilize AI tools to enhance decision-making, anticipate risks, and ensure timely outcomes. Collaborate with stakeholders to ma...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Engage with our team as a Senior Services Engineer, driving B2B integration and managed file transfer solutions. Ensure operational excellence and reliability in mission-critical systems while providi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$105K - $175K *

Lead the charge in Model-Based Systems Engineering, collaborating with experts across diverse domains to develop cutting-edge solutions. Utilize your skills in SysML and modeling tools to drive innova...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$80K - $110K *

Transform your career by developing innovative software solutions in a collaborative Agile environment. Engage in all phases of the software development lifecycle while enhancing cybersecurity and ide...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Drive platform architecture and strategy, owning scalable production environments. Lead cross-team collaboration, mentor engineers, and advocate for DevSecOps practices while solving complex technical...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $150K *

Unlock potential by leading software engineering initiatives, mentoring junior engineers, and driving improvements in development processes. Collaborate with stakeholders to deliver impactful solution...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$200K - $250K *

Champion product security initiatives by leading a skilled team, architecting compliance frameworks, and managing incident response to enhance trust across all products and stakeholders...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Transform your career by driving growth and client success in a dynamic market. Collaborate with cross-functional teams to enhance operational excellence, expand revenue, and deliver exceptional clien...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Lead the charge in transforming IT support for healthcare centers by evaluating, planning, and executing transitions to AMSURG Managed IT Services, while architecting cloud solutions with Microsoft 36...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$121K - $170K *

Advance your career by leading physical security solutions, driving operational excellence, and fostering team development. Collaborate across functions to enhance client outcomes and achieve strategi...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$171K - $257K *

Empower the future of Analytics & AI by leading technical sales initiatives, guiding teams, and driving customer engagement. Collaborate cross-functionally to enhance solutions and enablement, ensurin...

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$96K - $144K *

Lead the charge in delivering exceptional customer service and technical support at assigned medical equipment sites, ensuring compliance with contracts and fostering strong client relationships throu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$159K - $215K *

Take ownership of Windows endpoint reliability and lifecycle management. Enhance provisioning, patching, and automation while collaborating with cross-functional teams to drive improvements and mentor...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$106K - $160K *

Lead complex contract negotiations and drive strategic supplier relationships. Collaborate with stakeholders to assess risks, develop negotiation strategies, and enhance contracting practices while me...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$92K - $110K *

Unlock your potential by designing and optimizing scalable data solutions. Collaborate with cross-functional teams to enhance data reliability and efficiency while driving best practices in data manag...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$75K - $158K *

Shape the future of automation by managing the UiPath platform, ensuring security and performance while collaborating with cross-functional teams to deliver efficient robotic process solutions across...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.