Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$150K - $180K *
Transform technical leadership by overseeing Oracle architecture and AI delivery. Play a key role in building a high-performing team while engaging with customers and partners to drive innovative solu...
2 weeks ago
Workday PSA, Professional Services Automation Architect
$150K - $160K *
Champion the evolution of Workday PSA by architecting scalable solutions that integrate finance and operations. Lead major initiatives from design to implementation, ensuring alignment with global sta...
5 days ago
$103K - $185K *
Join a team that's focused on hands-on technical delivery while mentoring and developing team capabilities. Lead solution implementation, troubleshoot issues, and establish best practices to ensure hi...
5 days ago
Principal AI Transformation Consultant
$136K - $160K *
Drive transformation by partnering with architecture and engineering firms to enhance workflows through AI-enabled solutions. Collaborate with stakeholders to redefine processes, ensuring operational...
6 days ago
$140K - $150K *
Elevate security posture by driving the design and implementation of Zero Trust solutions. Play a pivotal role in enhancing enterprise cybersecurity for DoD clients, ensuring compliance with standards...
Reposted 4 weeks ago
Senior DevSecOps Engineer (Remote)
$140K - $160K *
Join a dynamic team as you architect secure CI/CD pipelines, manage Kubernetes clusters, and implement security automation in AWS. Collaborate across teams to enhance operational efficiency while embe...
1 week ago
$90K - $110K *
Shape customer success by designing tailored technical solutions and delivering impactful presentations. Collaborate with sales teams to leverage infrastructure, ensuring alignment with network capabi...
1 week ago
$125K - $150K *
Lead the charge in managing and optimizing cloud infrastructure across multiple platforms. Collaborate with teams to enhance product reliability and streamline operations while ensuring security and c...
3 weeks ago
$100K - $120K *
Elevate preconstruction processes by leading project planning, coordination, and execution. Collaborate with stakeholders to ensure alignment on scope, budget, and timelines while managing cost estima...
Reposted 3 days ago
$195K - $225K *
Drive security innovation by shaping technical strategies and frameworks that protect sensitive data and systems. Collaborate across teams to embed security practices, mentor engineers, and ensure com...
1 week ago
$160K - $229K *
Empower clients by designing and implementing innovative SAP FSM solutions. Collaborate across teams to ensure successful project delivery, from discovery to go-live, while enhancing business processe...
1 week ago
$225K - $265K *
Lead and mentor a diverse team of backend engineers in EDR remediation, transforming insights into actionable product capabilities while managing scope and fostering collaboration across engineering t...
1 week ago
AEC Healthcare Project Manager
$110K - $130K *
Shape the future of healthcare by leading complex architectural and facility projects, ensuring optimal client service and regulatory compliance throughout all project phases while guiding multidiscip...
Reposted 1 week ago
Senior Enterprise Services Identity Engineer (Dallas, TX LOCAL CANDIDATES ONLY)
$120K - $145K *
Join a team that's shaping secure identity solutions across the enterprise. Lead the design and implementation of identity and access controls, ensuring compliance and operational efficiency while col...
1 week ago
Backend Software Engineer - TS/SCI
$97K - $162K *
Innovate backend solutions for critical national security missions, developing APIs and data capabilities in cloud environments. Collaborate with Defense and Intelligence sectors to solve complex tech...
Reposted today
$104K - $153K *
Champion innovative AI-driven self-service solutions, enhancing employee experiences through ServiceNow. Collaborate with teams to streamline processes, ensuring high-quality engineering from design t...
2 weeks ago
$90K - $189K *
Lead the charge in coaching agile teams within a scaled framework, ensuring effective planning, execution, and continuous improvement in a collaborative environment while fostering strong stakeholder...
6 days ago
$90K - $189K *
Transform agile teams by coaching and facilitating effective Scrum practices, ensuring successful delivery of solutions in a scaled agile environment while fostering strong stakeholder relationships a...
6 days ago
$100K - $140K *
Discover your potential as you design and develop impactful web experiences, collaborating across teams to create engaging landing pages and brand sites that drive conversions and enhance user interac...
4 days ago
Strategic Solution Sales Executive, Business Networks
$140K - $185K *
Engage with strategic accounts to drive growth through solution sales. Collaborate with cross-functional teams to identify opportunities, articulate value, and influence client transformation initiati...
6 days ago
$80K - $95K *
Transform identity and access management by executing daily operations, supporting AI tooling, and managing SaaS vendor administration. This role offers hands-on experience and a clear growth path tow...
2 weeks ago
$150K - $180K *
Transform the future of quantum technology by leading product definition and architecture for a groundbreaking initiative. Collaborate with cross-functional teams to shape solutions and drive market e...
2 weeks ago
$150K - $180K *
Elevate our quantum technology initiative by leading product definition and architecture. Collaborate with cross-functional teams to shape solutions and engage with customers, driving innovation in a...
2 weeks ago
Technical Project Manager, Business Applications
$110K - $120K *
Drive impactful business application initiatives by leading cross-functional projects that enhance efficiency and performance. Collaborate with stakeholders to ensure successful delivery of Microsoft...
4 weeks ago
Director, Strategic Initiatives
$125K - $150K *
Lead the charge in driving strategic initiatives and optimizing enterprise portfolio execution. Collaborate with senior leadership to translate strategy into actionable priorities while overseeing Pro...
6 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.