Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$74K - $87K *
Transform client implementations by leading discovery, planning, and execution. Own project scope, timelines, and budgets to ensure successful adoption of solutions that align with business goals and...
4 days ago
Business Development Director, DOE
$157K - $283K *
Lead the charge in driving business growth by developing strategic partnerships and innovative solutions for federal clients, while collaborating with cross-functional teams to deliver exceptional res...
1 week ago
$144K - $200K *
Unlock potential by managing end-to-end technical deployments of computer vision systems. Collaborate with clients in diverse environments to ensure seamless production operations and enhance system p...
Reposted 3 days ago
Senior Full Stack Software Engineer (Go, AWS, GCP)
$165K - $260K *
Drive the development of an intelligent content delivery network, optimizing web performance through cutting-edge infrastructure and AI. Collaborate with a lean team to transform complex problems into...
Reposted 1 week ago
Program Manager, EPD Operations
$114K - $143K *
Drive operational excellence as a Program Manager, enhancing EPD processes and collaboration. Leverage data insights to identify trends, improve efficiency, and support cross-functional teams in a dyn...
2 weeks ago
$80K - $97K *
Shape the future of digital experiences by delivering innovative web solutions that enhance member engagement and drive growth. Collaborate with cross-functional teams to create intuitive, high-qualit...
2 weeks ago
Staff Engineer, Identity & Access Management (IAM)
$180K - $212K *
Pioneer innovative IAM strategies to enhance security across cloud and on-premise infrastructures. Collaborate with cross-functional teams to implement robust identity governance and access management...
3 weeks ago
Director of Applied AI Engineering
$207K - $290K *
Elevate your career by leading a dynamic Applied AI team, transforming innovative AI solutions into production-ready systems within a regulated financial environment, while collaborating across depart...
2 weeks ago
$110K - $130K *
Partner with us to design and implement cloud-native data solutions, ensuring secure and reliable data exchange across platforms. Collaborate with teams to enhance data accessibility and support advan...
1 week ago
Avionics/ Staff Command and Data Handling Engineer
$117K - $195K *
Join a team that's developing cutting-edge avionics architectures for diverse missions. Leverage your expertise in command and data handling to optimize system performance and ensure seamless integrat...
4 weeks ago
Staff Software Engineer, Firewall
$225K - $265K *
Unlock your potential as a technical leader, driving innovative solutions in Web Application Firewall integration. Collaborate across teams to enhance security and deliver impactful customer outcomes...
4 days ago
Senior Program Manager - Data Center Construction
$110K - $130K *
Take ownership of large-scale construction projects, managing stakeholders and ensuring compliance. Oversee project governance, track milestones, and enhance processes while fostering client relations...
Yesterday
Senior IT Engineer, Automation
$142K - $161K *
Unlock potential by automating IT processes and workflows. In this senior role, you'll own and enhance automation systems, ensuring reliability and efficiency while collaborating with cross-functional...
4 days ago
Professional Services Engineer
$100K - $120K *
Deliver exceptional consulting services by managing client implementations, diagnosing technical issues, and providing tailored solutions. Collaborate with cross-functional teams to ensure seamless in...
2 weeks ago
Director- Model Audit, Build and Transaction Advisory
$150K - $180K *
Partner with us to lead a dynamic model audit team, enhancing financial modelling processes while driving strategic growth and innovation across projects, all while fostering a collaborative and high...
Reposted 2 days ago
Senior Strategic Solutions Architect
$175K - $205K *
Transform the future of client technology by leading architectural strategies and integrations in life insurance and annuity environments, ensuring alignment with enterprise goals and delivering scala...
Reposted today
$90K - $189K *
Join a team that's dedicated to enhancing information technology solutions within the Department of the Air Force. Drive the implementation and modernization of Tenable architecture to ensure complian...
Reposted 2 weeks ago
$100K - $151K *
Lead the development and management of Reality Capture capabilities, enhancing design services through innovative technology and expert collaboration. Drive project integration, operational excellence...
3 weeks ago
Senior Backend Software Architect
$150K - $180K *
Innovate scalable backend systems while leading architectural design and mentoring teams. This role combines hands-on coding with strategic leadership to align technical solutions with business goals...
3 days ago
Senior/Staff Platform Engineer, Infrastructure & Security
$135K - $160K *
Optimize secure cloud infrastructure and automate compliance controls while enhancing operational efficiency. Collaborate with stakeholders to ensure reliability and security in a dynamic environment...
Yesterday
$135K - $150K *
Lead the charge in enhancing cybersecurity operations by managing incident response, mentoring SOC analysts, and developing processes to effectively identify and mitigate threats in a 24/7 Security Op...
Reposted 3 days ago
$90K - $110K *
Join a team that's dedicated to enhancing information security through proactive assessments and innovative solutions. Contribute to compliance and risk management while implementing best practices in...
4 days ago
Sr. Staff Software Engineer, Cribl AI
$250K - $300K *
Shape the future of observability data by integrating cutting-edge AI into core products. Collaborate with engineers to solve real customer challenges while innovating and refining user experiences ac...
Reposted today
Intellectual Property Security Engineer
$184K - $356K *
Engage in safeguarding intellectual property within engineering teams by establishing secure workflows, creating training materials, and managing security policies. Collaborate effectively across team...
Reposted 1 week ago
Senior Engineer (AWS, Azure, Terraform, Kubernetes)
$150K - $175K *
Lead innovative cloud solutions by architecting and managing robust platforms. Collaborate with a dynamic team to tackle complex challenges in AWS and Azure, enhancing your skills while driving impact...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.