Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Network Architect Jobs in Missouri

Sort By: Relevance

$74K - $87K *

Transform client implementations by leading discovery, planning, and execution. Own project scope, timelines, and budgets to ensure successful adoption of solutions that align with business goals and...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$157K - $283K *

Lead the charge in driving business growth by developing strategic partnerships and innovative solutions for federal clients, while collaborating with cross-functional teams to deliver exceptional res...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$144K - $200K *

Unlock potential by managing end-to-end technical deployments of computer vision systems. Collaborate with clients in diverse environments to ensure seamless production operations and enhance system p...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Staffing

$165K - $260K *

Drive the development of an intelligent content delivery network, optimizing web performance through cutting-edge infrastructure and AI. Collaborate with a lean team to transform complex problems into...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$114K - $143K *

Drive operational excellence as a Program Manager, enhancing EPD processes and collaboration. Leverage data insights to identify trends, improve efficiency, and support cross-functional teams in a dyn...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $97K *

Shape the future of digital experiences by delivering innovative web solutions that enhance member engagement and drive growth. Collaborate with cross-functional teams to create intuitive, high-qualit...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $212K *

Pioneer innovative IAM strategies to enhance security across cloud and on-premise infrastructures. Collaborate with cross-functional teams to implement robust identity governance and access management...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$207K - $290K *

Elevate your career by leading a dynamic Applied AI team, transforming innovative AI solutions into production-ready systems within a regulated financial environment, while collaborating across depart...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Partner with us to design and implement cloud-native data solutions, ensuring secure and reliable data exchange across platforms. Collaborate with teams to enhance data accessibility and support advan...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$117K - $195K *

Join a team that's developing cutting-edge avionics architectures for diverse missions. Leverage your expertise in command and data handling to optimize system performance and ensure seamless integrat...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$225K - $265K *

Unlock your potential as a technical leader, driving innovative solutions in Web Application Firewall integration. Collaborate across teams to enhance security and deliver impactful customer outcomes...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Take ownership of large-scale construction projects, managing stakeholders and ensuring compliance. Oversee project governance, track milestones, and enhance processes while fostering client relations...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$142K - $161K *

Unlock potential by automating IT processes and workflows. In this senior role, you'll own and enhance automation systems, ensuring reliability and efficiency while collaborating with cross-functional...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Deliver exceptional consulting services by managing client implementations, diagnosing technical issues, and providing tailored solutions. Collaborate with cross-functional teams to ensure seamless in...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Partner with us to lead a dynamic model audit team, enhancing financial modelling processes while driving strategic growth and innovation across projects, all while fostering a collaborative and high...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$175K - $205K *

Transform the future of client technology by leading architectural strategies and integrations in life insurance and annuity environments, ensuring alignment with enterprise goals and delivering scala...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$90K - $189K *

Join a team that's dedicated to enhancing information technology solutions within the Department of the Air Force. Drive the implementation and modernization of Tenable architecture to ensure complian...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $151K *

Lead the development and management of Reality Capture capabilities, enhancing design services through innovative technology and expert collaboration. Drive project integration, operational excellence...

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $180K *

Innovate scalable backend systems while leading architectural design and mentoring teams. This role combines hands-on coding with strategic leadership to align technical solutions with business goals...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Optimize secure cloud infrastructure and automate compliance controls while enhancing operational efficiency. Collaborate with stakeholders to ensure reliability and security in a dynamic environment...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $150K *

Lead the charge in enhancing cybersecurity operations by managing incident response, mentoring SOC analysts, and developing processes to effectively identify and mitigate threats in a 24/7 Security Op...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Join a team that's dedicated to enhancing information security through proactive assessments and innovative solutions. Contribute to compliance and risk management while implementing best practices in...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Business Services

$250K - $300K *

Shape the future of observability data by integrating cutting-edge AI into core products. Collaborate with engineers to solve real customer challenges while innovating and refining user experiences ac...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$184K - $356K *

Engage in safeguarding intellectual property within engineering teams by establishing secure workflows, creating training materials, and managing security policies. Collaborate effectively across team...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $175K *

Lead innovative cloud solutions by architecting and managing robust platforms. Collaborate with a dynamic team to tackle complex challenges in AWS and Azure, enhancing your skills while driving impact...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.