Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$130K - $180K *
Build a robust data foundation to elevate Market Intelligence. Drive automation and streamline data workflows, enriching insights for research and publishing, while ensuring data integrity and accessi...
Reposted 2 weeks ago
Senior Cloud Security Engineer (AWS & GCP)
$135K - $160K *
Champion cloud security excellence by engineering robust solutions across AWS and GCP. Drive vulnerability remediation, system hardening, and compliance for federal clients while mentoring junior engi...
1 week ago
Configuration Management (CM) Engineer
$90K - $110K *
Grow your career with a pivotal role in configuration management, ensuring system stability and compliance. Collaborate across teams to track changes, maintain documentation, and support deployments i...
1 week ago
eDiscovery Analyst, Enterprise Accounts
$100K - $120K *
Champion the management and execution of complex e-discovery projects, collaborating with legal teams to ensure successful outcomes. Oversee multiple projects while mentoring a team, maintaining quali...
2 weeks ago
$110K - $130K *
Shape the future of cloud-native applications by designing and developing scalable solutions that enhance Workforce Management and Customer Experience. Collaborate with cross-functional teams to deliv...
3 weeks ago
Director of Engineering, Product
$250K - $290K *
Elevate your career by leading a high-performing engineering team, driving strategy and innovation in web3 technologies. Shape the future of decentralized systems while ensuring top-tier security and...
Reposted today
Vice President - Construction Management (Data Centers)
$170K - $200K *
Unlock potential by overseeing large-scale data center construction projects, ensuring timely delivery, budget adherence, and quality standards while collaborating with diverse stakeholders across all...
Today
$100K - $120K *
Join a team that's dedicated to enhancing healthcare technology by developing and maintaining our Electronic Health Record platform using Ruby. Collaborate in an agile environment to deliver impactful...
2 weeks ago
Staff Engineer - INFOR M3 Functional Consultant (Supply Chain)
$110K - $130K *
Lead the configuration and support of Infor M3 non-finance modules, driving business process analysis and continuous improvement. Collaborate with teams to ensure effective implementation and user tra...
3 weeks ago
$125K - $220K *
Drive security excellence by leading a dynamic team to enhance our cloud platform's security posture. Collaborate across departments to ensure compliance, resilience, and customer trust while fosterin...
3 weeks ago
Senior Compliance Administrator - Network, Provider, Product
$87K - $157K *
Lead the charge in executing the Medicare Compliance Advisory program, ensuring adherence to CMS regulations. Collaborate with stakeholders to provide regulatory guidance, assess compliance risks, and...
1 week ago
$130K - $192K *
Join a team that's implementing robust security controls across multiple brands, safeguarding employees and enhancing productivity through automation and secure practices. Collaborate globally while l...
Reposted 2 weeks ago
Infrastructure Advisory & Transformation Senior Manager
$132K - $302K *
Elevate your career by leading transformative infrastructure strategies, guiding clients through modernization and cloud adoption, and driving measurable business outcomes in a dynamic advisory role...
1 week ago
Windows Platform Architect - Remote, USA
$240K - $250K *
Lead the charge in designing core Windows components, ensuring performance and stability for millions of users. Collaborate with global teams to innovate and enhance product efficiency while mentoring...
5 days ago
$72K - $100K *
Join our dynamic team as a Sr. Credit Analyst, owning the underwriting cycle from application review to decision-making. Leverage your analytical skills to enhance credit processes and contribute to a...
2 weeks ago
$95K - $115K *
Shape the future of defense programs by managing technology initiatives, supporting federal acquisitions, and driving business development efforts. Collaborate with diverse teams to translate complex...
Today
$165K - $195K *
Shape the future of enterprise technology services by owning service portfolios, driving lifecycle management, and ensuring operational readiness. Collaborate with cross-functional teams to align serv...
3 weeks ago
Senior Manager, Communications
$150K - $215K *
Innovate by driving real-time communications strategies and partner engagement. Shape impactful narratives during breaking news while building scalable programs that connect communications outcomes to...
2 weeks ago
$180K *
Drive the development of a cutting-edge platform, enhancing integrations and architecture for payroll and HR systems. Collaborate closely with a small team to ensure a successful launch and ongoing im...
6 days ago
$120K - $145K *
Unlock potential by leading IT operations and identity management, transforming strategy into action. Drive technical excellence in Microsoft Entra ID, endpoint platforms, and SaaS integrations while...
1 week ago
$90K - $110K *
Innovate structural designs for light gauge and cold-formed steel systems, ensuring compliance with California codes. Collaborate across teams to enhance manufacturability and efficiency in modular an...
Reposted today
Account Executive - Enterprise (San Diego)
$91K - $194K *
Champion new account acquisition in the enterprise market, driving sales success through collaboration and strategic engagement. Leverage your expertise to achieve sales goals and foster strong relati...
4 weeks ago
$110K - $130K *
Elevate our software engineering capabilities by designing and building modern, cloud-native data pipelines. Collaborate with diverse teams to ensure seamless project delivery and advocate for best pr...
3 weeks ago
$200K - $250K *
Lead the charge in embedding Domino into complex enterprise IT landscapes. Drive strategic deployments, design robust architectures, and enhance AI/ML integrations while collaborating with cross-funct...
2 weeks ago
$120K - $145K *
Drive the design and optimization of Oracle CX data architecture, ensuring effective data conversion and integration. Collaborate with cross-functional teams to enhance customer experience through inn...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.