Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$121K - $182K *
Partner with us to lead complex cloud migrations, ensuring technical readiness and seamless execution across Azure and AWS environments while driving innovative solutions and high-quality outcomes in...
5 days ago
Associate Director, Enterprise Architecture
$170K - $190K *
Shape the enterprise architecture landscape by aligning technology across core platforms, establishing standards, and driving strategic initiatives. Collaborate with cross-functional teams to enhance...
3 weeks ago
$110K - $130K *
Join a dynamic team to build and grow channel partnerships, driving revenue through strategic alliances with cloud providers. Leverage your expertise to recruit, enable, and activate partners while co...
2 weeks ago
$160K - $200K *
Drive innovation by designing and developing scalable backend services, collaborating closely with engineering teams to enhance platform performance and reliability while mentoring junior developers a...
3 weeks ago
Senior/Staff DevOps Engineer, Federal
$180K - $240K *
Join us to build and operate secure infrastructure for federal and partner environments. This hands-on role focuses on Kubernetes, infrastructure as code, and production support, ensuring reliable dep...
4 days ago
IT System Administrator - SOC/NOC Support
$106K - $221K *
Drive the future of cybersecurity by managing SOC/NOC tools, optimizing performance, and implementing security controls to ensure robust system operations and compliance with best practices...
Today
Data Center Operations System Engineer - Plano, TX
$95K - $115K *
Advance your career by ensuring optimal performance of critical data center infrastructure. Collaborate with teams to troubleshoot, document, and manage hardware and software systems in a fast-paced e...
1 week ago
Senior Solution Architect - Geospatial - 1898 & Co.
$120K - $145K *
Lead the charge in architecting innovative geospatial solutions, guiding strategic investments, and aligning technology with business objectives to transform client operations and enhance program effi...
1 week ago
$96K - $115K *
Lead the charge in designing and developing aerospace wire harnesses, ensuring compliance with industry standards while collaborating with multidisciplinary teams to deliver innovative solutions...
Reposted today
$75K - $158K *
Contribute to the security of critical Oracle systems by designing and implementing cyber controls. Collaborate with teams to ensure compliance, support testing phases, and produce quality deliverable...
Reposted 2 weeks ago
$95K - $115K *
Lead and enhance day-to-day accounting operations, focusing on accounts payable, receivable, and cash management. Collaborate with cross-functional teams to ensure accurate, timely transactions while...
1 week ago
Consulting Solution Executive – Hybrid Infrastructure
$91K - $127K *
Unlock your potential by driving growth in Hybrid Infrastructure solutions. Lead strategic account management, cultivate relationships, and enhance market presence while achieving sales targets in a d...
3 weeks ago
Director, Technology Integration Delivery
$140K - $175K *
Elevate your career by leading technology integration for M&A, ensuring seamless execution from due diligence to stabilization. Drive cross-functional collaboration and deliver predictable outcomes wh...
2 weeks ago
Director, Technology Integration Delivery
$140K - $175K *
Deliver comprehensive technology integration leadership for M&A activities, ensuring seamless execution from due diligence to stabilization. Drive cross-functional collaboration, manage resources, and...
2 weeks ago
$125K - $140K *
Elevate your career by designing and managing AWS environments, automating CI/CD, and ensuring robust application delivery. Collaborate with cross-functional teams for end-to-end ownership and enhance...
Reposted yesterday
$94K - $126K *
Accelerate growth in assigned territory by developing strategic sales capabilities, managing key accounts, and collaborating with team members to close sales opportunities while ensuring customer sati...
1 week ago
$125K - $135K *
Join a dynamic team as you drive Agile Release Train initiatives, coordinate diverse product teams, and ensure effective delivery in a complex environment. Your leadership will enhance collaboration a...
Reposted yesterday
$145K - $185K *
Transform the Cyber operations landscape by leading business development, shaping solutions, and executing contracts. Build trusted relationships, manage a diverse portfolio, and drive customer satisf...
Reposted 1 week ago
$95K - $115K *
Execute comprehensive project controls to ensure timely, budget-compliant project completion. Collaborate with teams to analyze financial data, manage forecasts, and report on project progress across...
2 weeks ago
$104K - $166K *
Optimize your career by ensuring the performance and scalability of critical AWS platforms. Collaborate with cross-functional teams to deliver secure, automated solutions while enhancing operational e...
5 days ago
$104K - $166K *
Elevate the performance and reliability of critical AWS cloud platforms. Collaborate with cross-functional teams to optimize infrastructure, automate processes, and ensure secure, scalable solutions t...
6 days ago
Technical Application Engineer - Industrial Communications products (MDS and Lentronics)
$89K - $148K *
Drive technical solutions by collaborating with sales teams and customers to enhance industrial communications products. Develop sales strategies, manage customer relationships, and ensure compliance...
Reposted 2 weeks ago
Software Engineer 5 - Training Platform, AI Platform
$466K - $500K+*
Join a team that's shaping the future of AI by designing and building scalable platforms for large-scale machine learning model training, enhancing performance, and creating user-friendly experiences...
5 days ago
Senior Security Consultant, Application Security
$75K - $175K *
Advance application security initiatives by leading manual code reviews, penetration tests, and threat modeling. Work closely with clients to strengthen their secure development processes, delivering...
Reposted 3 weeks ago
Department Leader - Solution Architecture
$130K - $155K *
Lead the architectural vision for technology platforms, guiding a team of Solution Architects to enhance client experiences and drive strategic initiatives. Shape best practices and foster growth thro...
4 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.