Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Software Engineer II, Engineering
$125K - $145K *
Lead the charge in building impactful software features that enhance educators' management of English Learner programs, taking ownership from design to operation in a full-stack environment utilizing...
Reposted 2 weeks ago
Principal Network Installation Technician (NIT 4)
$110K - $130K *
Champion complex network installation projects by leading teams, mentoring technicians, and ensuring high-quality service delivery. Collaborate with project managers and customers to meet objectives w...
3 weeks ago
Lead Salesforce Technical Architect (Remote)
$160K - $205K *
Champion innovative Salesforce solutions by leading architecture and integration efforts. Collaborate with stakeholders to enhance CRM capabilities, ensuring secure and efficient digital services whil...
1 week ago
Solutions Architect (Contract)
$156K - $187K *
Transform the data landscape by designing and implementing robust integration solutions. Collaborate with cross-functional teams to enhance analytics infrastructure, ensuring seamless data flow and go...
4 weeks ago
Sr Information Security Specialist
$110K - $130K *
Lead the operational execution of complex information security activities, ensuring effective protection of systems and data. Collaborate across teams to enhance security processes and manage incident...
1 week ago
$190K - $210K *
Explore innovative solutions as you lead the design and architecture of scalable healthcare applications, mentor engineers, and collaborate with cross-functional teams to enhance patient experiences a...
Today
$117K - $143K *
Empower small businesses by developing AI solutions that streamline workflows. Collaborate closely with customers to identify challenges and create impactful software that enhances efficiency and driv...
1 week ago
Senior Cyber Security Consultant
$110K - $130K *
Shape the future of cybersecurity in higher education by delivering expert assessments, advisory services, and tailored remediation plans that empower institutions to enhance their security posture an...
Reposted 6 days ago
Database Engineer - Oracle & Cloud Platforms
$106K - $176K *
Optimize enterprise database services in a secure hybrid-cloud environment. As a senior technical resource, ensure performance, security, and reliability while supporting cloud adoption and modernizat...
2 weeks ago
Mid-Market Account Executive, Networks
$142K - $215K *
Elevate your career by driving new business growth in a dynamic sales environment. Own the full sales cycle, collaborate with teams, and exceed revenue goals while engaging with key stakeholders in a...
1 week ago
$110K - $130K *
Engineer robust backend systems for financial applications, tackling payments, fraud detection, and compliance. Collaborate with a skilled team to design, build, and optimize features, ensuring reliab...
2 weeks ago
$80K - $95K *
Transform your career by enhancing data security and integrity. Collaborate with cross-functional teams to implement robust security measures, conduct audits, and mitigate risks while staying ahead of...
3 weeks ago
Forward Deployed Engineer, AI & Agentforce
$110K - $130K *
Join a team that's redefining AI solutions by rapidly delivering innovative, client-focused engagements. Collaborate with stakeholders to architect impactful agentic solutions that drive business valu...
2 weeks ago
Fire Alarm Engineering Manager
$110K - $130K *
Elevate your career by leading a dynamic engineering team in fire alarm design. Drive innovative solutions, optimize project performance, and collaborate across departments to ensure compliance and qu...
2 weeks ago
$110K - $130K *
Drive innovative software solutions by designing, developing, and testing systems-level software. Collaborate with cross-functional teams to meet operational specifications and enhance SAP functionali...
3 weeks ago
Senior Engineer, Partner Integrations Platform
$145K - $160K *
Drive innovation by building scalable data integration solutions, collaborating with cross-functional teams to enhance healthcare technology. Ensure data quality and security while optimizing performa...
6 days ago
Fire Alarm Engineering Manager
$110K - $130K *
Join a team that's shaping the future of fire alarm systems by leading design projects, mentoring engineers, and driving innovative solutions that meet performance and regulatory standards while ensur...
2 weeks ago
Team Lead, Software Development
$110K - $130K *
Elevate team performance by leading a Scrum team in developing and modernizing enterprise SaaS applications. Guide technical decisions, mentor engineers, and foster collaboration across departments to...
4 weeks ago
Member of Technical Staff, Product & Engineering
$125K - $150K *
Drive AI-native software development by architecting systems, guiding AI agents, and ensuring quality. Collaborate closely with users to transform business needs into reliable, efficient solutions whi...
1 week ago
Project Manager, Engineering - Mission Critical
$108K - $130K *
Transform project delivery by leading multidisciplinary teams in high-stakes engineering design for Mission Critical and Data Center projects, ensuring excellence from concept to construction while me...
Reposted 1 week ago
$100K - $120K *
Drive partner success by developing key relationships and executing strategic business plans in the Latin America region, enhancing revenue through effective channel programs and collaboration with sa...
3 weeks ago
Principal Backend Engineer, Enterpise Platform
$255K - $295K *
Lead the technical direction for foundational services, guiding architecture and execution across teams to enhance platform capabilities for customer and partner experiences. Mentor engineers and infl...
Today
$110K - $130K *
Join a dynamic team to oversee CMMC compliance, ensuring strategic coordination across stakeholders and technical teams. Drive project execution, monitor KPIs, and facilitate continuous improvement in...
Yesterday
$120K - $145K *
Unlock potential by leading complex engineering initiatives across Microsoft 365 collaboration services, ensuring secure, reliable solutions while mentoring engineers and enhancing platform health thr...
2 weeks ago
$160K - $190K *
Champion innovative solutions as a Technical Architect, leading customer engagements to integrate Salesforce and AI technologies. Drive adoption and optimize implementations while mentoring teams and...
6 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.