Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Network Architect Jobs in Missouri

Sort By: Relevance

$125K - $145K *

Lead the charge in building impactful software features that enhance educators' management of English Learner programs, taking ownership from design to operation in a full-stack environment utilizing...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Champion complex network installation projects by leading teams, mentoring technicians, and ensuring high-quality service delivery. Collaborate with project managers and customers to meet objectives w...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $205K *

Champion innovative Salesforce solutions by leading architecture and integration efforts. Collaborate with stakeholders to enhance CRM capabilities, ensuring secure and efficient digital services whil...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$156K - $187K *

Transform the data landscape by designing and implementing robust integration solutions. Collaborate with cross-functional teams to enhance analytics infrastructure, ensuring seamless data flow and go...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the operational execution of complex information security activities, ensuring effective protection of systems and data. Collaborate across teams to enhance security processes and manage incident...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$190K - $210K *

Explore innovative solutions as you lead the design and architecture of scalable healthcare applications, mentor engineers, and collaborate with cross-functional teams to enhance patient experiences a...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$117K - $143K *

Empower small businesses by developing AI solutions that streamline workflows. Collaborate closely with customers to identify challenges and create impactful software that enhances efficiency and driv...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Shape the future of cybersecurity in higher education by delivering expert assessments, advisory services, and tailored remediation plans that empower institutions to enhance their security posture an...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$106K - $176K *

Optimize enterprise database services in a secure hybrid-cloud environment. As a senior technical resource, ensure performance, security, and reliability while supporting cloud adoption and modernizat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$142K - $215K *

Elevate your career by driving new business growth in a dynamic sales environment. Own the full sales cycle, collaborate with teams, and exceed revenue goals while engaging with key stakeholders in a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Engineer robust backend systems for financial applications, tackling payments, fraud detection, and compliance. Collaborate with a skilled team to design, build, and optimize features, ensuring reliab...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $95K *

Transform your career by enhancing data security and integrity. Collaborate with cross-functional teams to implement robust security measures, conduct audits, and mitigate risks while staying ahead of...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's redefining AI solutions by rapidly delivering innovative, client-focused engagements. Collaborate with stakeholders to architect impactful agentic solutions that drive business valu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Elevate your career by leading a dynamic engineering team in fire alarm design. Drive innovative solutions, optimize project performance, and collaborate across departments to ensure compliance and qu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Drive innovative software solutions by designing, developing, and testing systems-level software. Collaborate with cross-functional teams to meet operational specifications and enhance SAP functionali...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$145K - $160K *

Drive innovation by building scalable data integration solutions, collaborating with cross-functional teams to enhance healthcare technology. Ensure data quality and security while optimizing performa...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's shaping the future of fire alarm systems by leading design projects, mentoring engineers, and driving innovative solutions that meet performance and regulatory standards while ensur...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Elevate team performance by leading a Scrum team in developing and modernizing enterprise SaaS applications. Guide technical decisions, mentor engineers, and foster collaboration across departments to...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Drive AI-native software development by architecting systems, guiding AI agents, and ensuring quality. Collaborate closely with users to transform business needs into reliable, efficient solutions whi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$108K - $130K *

Transform project delivery by leading multidisciplinary teams in high-stakes engineering design for Mission Critical and Data Center projects, ensuring excellence from concept to construction while me...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $120K *

Drive partner success by developing key relationships and executing strategic business plans in the Latin America region, enhancing revenue through effective channel programs and collaboration with sa...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$255K - $295K *

Lead the technical direction for foundational services, guiding architecture and execution across teams to enhance platform capabilities for customer and partner experiences. Mentor engineers and infl...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a dynamic team to oversee CMMC compliance, ensuring strategic coordination across stakeholders and technical teams. Drive project execution, monitor KPIs, and facilitate continuous improvement in...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Unlock potential by leading complex engineering initiatives across Microsoft 365 collaboration services, ensuring secure, reliable solutions while mentoring engineers and enhancing platform health thr...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$160K - $190K *

Champion innovative solutions as a Technical Architect, leading customer engagements to integrate Salesforce and AI technologies. Drive adoption and optimize implementations while mentoring teams and...

6 days ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.