Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Principal Embedded Software Engineer
$116K - $157K *
Elevate your career by developing innovative embedded software solutions for defense industries. Collaborate with cross-functional teams to design, code, and test robust applications while leading pro...
4 days ago
Project Manager Data Center Rapid Deployment
$115K - $138K *
Manage complex data center deployment projects, ensuring timely delivery and alignment among stakeholders. Oversee planning, execution, and closeout while maintaining budget and risk controls in fast...
2 weeks ago
MEP Project Manager - Data Center
$95K - $115K *
Take ownership of MEP project management, ensuring seamless execution of mechanical, electrical, and plumbing systems on complex commercial and industrial projects while collaborating with diverse tea...
Reposted today
Critical Mechanical Systems Specialist
$110K - $130K *
Advance mechanical systems readiness by overseeing commissioning, conducting site inspections, and ensuring operational efficiency across critical infrastructure. Collaborate cross-functionally to enh...
6 days ago
MarTech Multi-Solution Lead Technical Architect
$134K - $265K *
Transform the marketing technology landscape by architecting innovative, AI-driven solutions that unify customer experiences across platforms, enabling seamless integration and omnichannel personaliza...
3 weeks ago
MarTech Multi-Solution Lead Technical Architect
$134K - $265K *
Unlock potential by architecting innovative MarTech solutions that integrate AI and enhance customer experiences across diverse platforms, driving impactful marketing strategies and leading cross-func...
3 weeks ago
$90K - $108K *
Support clients by providing strategic IT guidance to maximize technology investments, ensuring alignment with business goals. Manage relationships, deliver reports, and enhance security posture while...
1 week ago
Full Stack Software Engineer - Secret
$103K - $181K *
Shape the future of secure software by developing full-stack applications that support critical government missions. Collaborate with diverse teams to deliver reliable, scalable solutions in dynamic e...
3 weeks ago
$90K - $110K *
Unlock your potential by designing advanced PCB layouts and collaborating on innovative RF designs. This remote role requires expertise in Altium and a strong understanding of PCB standards to drive q...
1 week ago
Business Development Manager - Collaborative Engineering & Construction (Kansas City)
$110K - $130K *
Lead the charge in expanding our private client portfolio by driving strategic deal flow and managing collaborative engineering projects. Collaborate with teams to ensure successful project execution...
2 weeks ago
Senior IT Engineer, Network and Telecommunications
$95K - $115K *
Join a team that's driving innovation in network and telecommunications. You'll lead complex projects, mentor peers, and enhance operational processes to ensure robust infrastructure solutions that al...
3 weeks ago
Manager, Security Architecture
$160K - $200K *
Lead the charge in defining and executing security architecture strategies, focusing on identity, access, and Zero Trust initiatives. Collaborate across teams to enhance security posture while enablin...
5 days ago
$63K - $111K *
Join a team that's dedicated to enhancing security systems globally. As a Senior Security Technician, you'll install, maintain, and troubleshoot advanced security solutions while mentoring junior staf...
3 days ago
$170K - $230K *
Engineer the future of edge-AI by converting customer evaluations into design wins. Collaborate with engineering teams to optimize workloads on our innovative Chimera architecture, shaping the next ge...
Reposted 1 week ago
Senior Data & AI Platform Engineer
$125K - $150K *
Join a dynamic team to design and build a robust data platform that enhances product performance and supports AI initiatives, ensuring data integrity and accessibility for internal and customer-facing...
4 weeks ago
$92K - $153K *
Drive the design and implementation of security controls in AWS cloud environments, ensuring compliance with security frameworks while collaborating with engineering teams to enhance secure CI/CD proc...
1 week ago
$106K - $152K *
Join a team that's dedicated to securing communications systems by designing and implementing COMSEC protocols. Collaborate with cross-functional teams to ensure data integrity and compliance in dynam...
3 days ago
$110K - $130K *
Elevate data engineering capabilities by designing robust ETL/ELT workflows, ensuring data quality, and implementing scalable solutions on AWS and Kubernetes. Collaborate with teams to optimize perfor...
3 weeks ago
Cloud Infrastructure Architect - Remote
$120K - $160K *
Drive the design and management of cloud infrastructure, ensuring secure, scalable systems that align IT operations with business goals. Lead initiatives in automation and DevSecOps to enhance operati...
1 week ago
$120K - $150K *
Engage your expertise to drive revenue growth through strategic enterprise sales. Lead customer relationships across diverse sectors, analyze market trends, and implement effective sales strategies wh...
4 weeks ago
$80K - $90K *
Transform the IT landscape by enhancing cloud services and user systems. Play a key role in optimizing platforms like Azure, O365, and Jira, while driving efficiencies through automation and collabora...
Reposted today
Business Development Manager, Security - Central
$95K - $115K *
Empower your career by driving top-of-funnel growth and cultivating key end user relationships in vertical markets, influencing specifications early in design processes while collaborating with intern...
Reposted today
Business Development Manager, Security - Central
$95K - $115K *
Optimize business development efforts by driving early-stage opportunity creation in key verticals, engaging decision-makers, and fostering long-term relationships to support growth strategies and rev...
Reposted today
$140K - $160K *
Elevate your career by joining a dynamic team as a Data Engineer, owning end-to-end data systems and driving platform modernization. You'll improve data reliability and work closely with cross-functio...
Reposted 3 weeks ago
$160K - $180K *
Elevate customer success by managing strategic federal programs, ensuring seamless implementation and adoption of innovative solutions. Collaborate with stakeholders to drive project execution and enh...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.