Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$120K - $200K *
Drive account growth by managing client relationships and fostering strategic partnerships. This dynamic role engages with clients, executing sales strategies to expand product adoption while ensuring...
Reposted 6 days ago
Lead Infrastructure Engineer - Hybrid Cloud & Automation Solutions
$130K - $155K *
Optimize and implement scalable, secure infrastructure solutions across Windows, Citrix, AWS, and Azure. Drive automation and collaborate with teams to design zero-trust architectures, enhancing infra...
4 weeks ago
$99K - $132K *
Empower your career by leveraging technology to drive innovative solutions. Collaborate with sales teams to analyze customer needs, architect tailored solutions, and present compelling proposals that...
Yesterday
$99K - $132K *
Join a team that's shaping the future of technology solutions. Leverage your technical and sales expertise to architect innovative solutions that drive business value for enterprise customers in a dyn...
4 days ago
Site Civil, Structural & Architectural Lead (CSLA)
$120K - $145K *
Champion the delivery of civil works and architectural projects, overseeing contractors and ensuring high-quality execution from site prep to completion. Leverage your expertise to manage complex site...
1 week ago
$100K - $160K *
Take ownership of technical consulting and integration for grid management systems, ensuring accuracy and operational usability within electric utility sectors. Drive solution delivery through system...
Reposted 1 week ago
$90K - $110K *
Accelerate talent acquisition by partnering with leaders to build candidate pipelines, drive recruiting efforts, and ensure timely hiring across corporate functions in a dynamic, project-driven enviro...
1 week ago
Principal Subcontract Administrator
$112K - $196K *
Lead subcontract administration efforts, ensuring compliance and effective negotiation while fostering relationships with suppliers and stakeholders. Drive strategic procurement initiatives within the...
2 weeks ago
Salesforce Agentforce Architect (Technical Architect)
$94K - $266K *
Unlock innovative AI solutions by leading technical designs and deployments across Agentforce and Salesforce. Collaborate with diverse teams to deliver impactful experiences and drive business value w...
4 weeks ago
Director, Managed Services-Voice & Services
$116K - $145K *
Elevate operational excellence by leading technical escalation and onboarding teams in Managed Services. Drive high-quality service delivery across voice, SD-WAN, and security, ensuring seamless custo...
1 week ago
Director, Managed Services-Voice & Services
$116K - $145K *
Join a team that's redefining managed services by leading technical escalations and customer onboarding for voice services. Drive operational excellence and ensure high-quality service delivery across...
1 week ago
$130K *
Shape the future of telecommunications by leading complex, large-scale projects. Drive strategic planning, manage executive communications, and ensure program success through innovative solutions and...
2 days ago
$90K - $110K *
Join a team that's dedicated to enhancing security design processes, ensuring high-quality project delivery, and collaborating with designers and project managers to drive efficiency in mission-critic...
3 weeks ago
$90K - $110K *
Drive IT operations excellence by leading a hands-on team, enhancing service delivery, and optimizing internal systems while actively engaging in technical troubleshooting and support...
3 weeks ago
$100K - $120K *
Drive innovative process design by leading teams, mentoring talent, and ensuring compliance with industry standards. Collaborate with clients to refine deliverables and enhance workflows, fostering co...
2 weeks ago
Staff Engineer - Product Development (Contact Systems)
$110K - $130K *
Lead innovative product development in power connectors and cable assemblies, driving technical excellence and cross-functional collaboration to deliver high-quality solutions that meet market demands...
Today
$120K - $145K *
Drive technology strategy by aligning investments with business goals, modernizing applications, and managing risk. Serve as a trusted advisor to leadership, establishing roadmaps and governance for a...
3 days ago
Technical Success Manager- Central
$100K - $120K *
Elevate customer success by leveraging technical expertise and advocacy to drive adoption of cybersecurity solutions, ensuring measurable outcomes and risk reduction through strategic partnerships wit...
1 week ago
Senior Platform Engineer -AI / Platform Lead
$135K - $160K *
Transform your career by leading platform engineering initiatives that enhance developer experience and operational excellence. Drive technical ownership across the software lifecycle, shaping the pla...
2 weeks ago
$180K - $200K *
Join us as a Principal Architect to drive technical innovation and unify systems across platforms. Collaborate with teams to design cloud-based solutions, mentor engineers, and enhance product deliver...
3 days ago
$110K - $130K *
Champion customer solutions by rapidly prototyping and deploying AI-driven applications. Collaborate with cross-functional teams to enhance product capabilities and drive adoption, ensuring impactful...
1 week ago
Senior AI & Cyber Defense Specialist
$120K - $145K *
Join a team that's redefining cybersecurity by leveraging AI to enhance defense strategies. Engage with customers across the Americas, translating complex concepts into actionable insights while drivi...
5 days ago
$100K - $150K *
Lead the charge in managing complex, technically sophisticated projects, focusing on data centers. Collaborate with diverse stakeholders to ensure project alignment with client goals, budgets, and sch...
Reposted today
Principal Procore Administrator
$113K - $170K *
Join us as a Principal Procore Administrator to lead configuration, governance, and enhancement of Procore for enterprise facilities and construction operations, ensuring data integrity while collabor...
Reposted 2 weeks ago
Director, Technology Partner Architecture Solutions – Legal
$157K - $292K *
Elevate legal technology solutions by leading architecture design and integration with partners. Collaborate across teams to ensure scalable, secure offerings that meet customer needs while guiding a...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.