Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Sr. Staff Applied AI Engineer, GTM
$180K - $225K *
Lead the charge in transforming AI strategies into impactful solutions for revenue teams, collaborating closely with GTM leaders to drive innovation and measurable outcomes while enhancing engineering...
1 week ago
$130K - $135K *
Join a team that's dedicated to enhancing federal cybersecurity compliance through advanced risk management and governance. Leverage your expertise to conduct assessments, manage authorizations, and e...
3 weeks ago
$80K - $95K *
Deliver impactful telecom design solutions by overseeing projects, enhancing production efficiency, and collaborating with designers and project managers to meet quality standards and client expectati...
3 weeks ago
Senior Full-Stack Cloud Developer
$102K - $170K *
Lead the charge in full-stack development, collaborating on enterprise modernization with Microservices. Deliver high-quality software, mentor engineers, and ensure best practices for cloud technologi...
Reposted 3 weeks ago
Project Executive, Data Centers
$190K - $230K *
Champion large-scale electrical construction projects in a dynamic data center environment. Lead teams to ensure successful delivery, maintain budgets, and foster client relationships while achieving...
2 weeks ago
IoT Engineer - Special Projects & Innovation
$99K - $120K *
Join our innovative team to architect and deliver cutting-edge IoT systems for special projects. You'll drive initiatives from concept to field pilot, integrating advanced technologies in a dynamic, c...
4 days ago
$218K - $273K *
Champion the global technical alliance with Snowflake and Databricks, driving co-sell revenue through strategic planning, technical narratives, and collaborative execution across teams and events, whi...
3 weeks ago
Technical Customer Support Engineer
$80K - $90K *
Join a team that's dedicated to delivering exceptional technical support for complex technologies, ensuring global customer satisfaction and product quality through collaborative troubleshooting and i...
Reposted 2 weeks ago
$90K - $110K *
Join a team that's dedicated to enhancing digital experiences for a Federal Government program. As a Web Developer, you'll build and maintain websites, ensuring accessibility and performance while col...
3 weeks ago
Mid-Level Grid Modernization Engineer
$107K - $177K *
Lead innovative grid modernization projects for electric utilities, enhancing distribution systems through advanced engineering solutions. Collaborate with clients and teams to improve reliability, ef...
1 week ago
$75K - $158K *
Unlock potential by serving as a key Business Analyst/Product Manager in a Scaled Agile environment, translating business objectives into actionable features and capabilities, while collaborating acro...
1 week ago
Senior Technical Lead / Solution Architect
$130K - $216K *
Lead the technical implementation of a large-scale platform modernization program, ensuring adherence to architectural standards and providing hands-on guidance across multiple teams and vendors for s...
2 weeks ago
Data Architect [ Must Have EPIC Caboodle $ Population Health ]
$110K - $130K *
Engineer innovative data solutions to optimize population health, enhance quality care analytics and reporting, while ensuring data governance and compliance within the healthcare domain. Collaborate...
Reposted 4 days ago
Senior/Staff Platform Engineer, Enterprise Deployments
$135K - $160K *
Champion customer success by leading enterprise deployments and integrations. Drive technical direction and enhance automation for cloud services, ensuring seamless operations and improved customer ex...
Yesterday
Cyber Data Analyst Engineer III
$101K - $111K *
Contribute to the design and maintenance of automated infrastructure, leveraging Kubernetes and Ansible. Engage with customers to enhance server lifecycle processes and ensure optimal CI/CD performanc...
3 weeks ago
Cloud Computing, Senior Advisor
$112K - $179K *
Optimize cloud infrastructure and CI/CD processes as a Cloud DevOps Engineer. Collaborate with Agile teams to enhance security, automate deployments, and ensure mission-critical support while leveragi...
4 days ago
Director of Services - US West
$150K - $200K *
Engage in leading a dynamic team dedicated to delivering top-notch offensive security engagements, ensuring delivery quality and client satisfaction, while collaborating with sales to expand accounts...
Reposted 4 weeks ago
Senior AI Engineer with RAG and Agentic architectures
$138K - $165K *
Champion the development of LLM-powered applications and agentic systems. Drive complex use cases from ambiguous problems to production, ensuring high-quality and scalable AI solutions that address us...
Reposted 4 days ago
$127K - $237K *
Join a team that's driving digital transformation by enhancing products and services, managing strategic initiatives, and developing talent to achieve organizational goals while ensuring optimal perfo...
Reposted 3 days ago
Senior Solutions Engineer (NY/NJ/PA)
$163K - $245K *
Optimize enterprise application delivery and security solutions by partnering with key stakeholders to design and implement modern architectures across multi-cloud environments, driving innovation and...
1 week ago
Principal Engineer, Monetization Engineering
$223K - $317K *
Drive the evolution of a robust Fulfillment platform, shaping architecture and strategy while mentoring teams. Lead modernization efforts to enhance scalability, reliability, and performance, ensuring...
2 weeks ago
$80K - $95K *
Lead the charge in overseeing complex industrial construction projects nationwide, ensuring safety, quality, and timely execution while mentoring field teams and coordinating trade partners for optima...
4 weeks ago
Senior Manager, Water Infrastructure
$180K - $200K *
Lead water infrastructure strategies, ensuring efficient design and compliance across data center projects. Collaborate with teams to secure agreements and manage risks, enhancing sustainability and c...
1 week ago
$98K - $206K *
Transform your career by joining our team to enhance Microsoft 365 services. Leverage your expertise in Teams, OneDrive, and SharePoint to provide operational support and drive improvements in reliabi...
Today
Micro-Architect and RTL Designer
$160K - $500K+*
Drive innovative silicon design methodologies, overseeing subsystem and chip-level deliverables from micro-architecture to sign-off. Collaborate with cross-functional teams to achieve optimal performa...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.