Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$93K - $125K *
Take ownership of advanced concept evaluations and development efforts. Collaborate with cross-functional teams to architect solutions, lead initiatives, and enhance technology strategies. Drive innov...
Reposted 3 days ago
$130K - $216K *
Transform enterprise Databricks environments with innovative designs, ensuring secure, efficient implementations while collaborating with stakeholders to deliver scalable data solutions and enhance go...
Reposted 2 weeks ago
$110K - $145K *
Strategize initiatives to enhance workforce alignment and Agile practices, driving high performance in IT services for federal clients while fostering a collaborative culture and supporting strategic...
2 weeks ago
Engineering Manager, Object Storage
$150K - $180K *
Lead a talented team in crafting a high-quality, scalable object storage product that enhances the developer experience, balancing technical execution with product thinking to drive meaningful improve...
Reposted 1 week ago
Principal Cloud Engineer - AI Platform
$175K - $250K *
Shape the cloud infrastructure for AI agents, ensuring secure, scalable solutions that enhance customer workflows. Lead architectural decisions, establish standards, and drive innovation in a dynamic...
Reposted 3 days ago
$153K - $230K *
Engage with cross-functional teams to manage program performance, ensuring technical compliance and effective communication with stakeholders. Drive project success in a fast-paced environment focused...
Reposted today
Technical Services Engineer - Federal
$125K - $150K *
Join a team that's dedicated to providing exceptional post-sales technical support for federal clients. You'll troubleshoot complex systems, collaborate with engineering teams, and ensure seamless ope...
2 weeks ago
Global Strategic Account Director
$115K - $135K *
Drive strategic growth by managing a diverse portfolio of accounts. Lead and mentor an account management team to enhance client relationships and maximize profitability through innovative solutions a...
2 weeks ago
Director Software Engineering - Central Security
$180K - $220K *
Drive the development of innovative security systems using AI/ML, managing risk across identity and access management. Collaborate with cross-functional teams to enhance security while maintaining ope...
1 week ago
Corporate Account Executive - SMB- East
$170K - $200K *
Accelerate sales growth by managing key partnerships and driving cloud solutions. Collaborate with teams to achieve targets, nurture relationships, and deliver exceptional customer experiences while s...
5 days ago
Adobe target Architect - MarTech
$110K - $130K *
Transform the future of digital engagement by leading Adobe Target implementations. Collaborate across teams to develop personalized strategies that enhance user experiences and drive measurable busin...
6 days ago
Senior Principal Network Engineer - 176774 - 17714 - 177643
$160K - $190K *
Join us to lead network modernization initiatives, collaborating with cross-functional teams to design and implement scalable, secure communication networks that support mission objectives. Drive stra...
3 days ago
Security Engineer 4 (SWG, Remote Access)
$179K - $204K *
Champion innovative security solutions by designing automated controls and cloud architectures. Collaborate with cross-functional teams to enhance enterprise security and drive technical transformatio...
2 weeks ago
$150K - $200K *
Champion transformative solutions by leading Salesforce implementations and optimizing client engagements. Leverage your expertise to deliver impactful results while driving project success, enhancing...
Reposted 2 weeks ago
Senior Software Engineer, Core Infrastructure Services - DGX Cloud
$168K - $322K *
Build and operate core infrastructure services for global AI platforms, developing secure cloud-native solutions and orchestrating automation to enhance reliability and scalability in a collaborative...
Reposted 1 week ago
$95K - $115K *
Unlock your potential by developing innovative software solutions using C#, .NET, and Azure. Collaborate with cross-functional teams to enhance business operations and drive technology initiatives tha...
5 days ago
$175K - $185K *
Engage with Federal agencies and software providers to design and implement secure cloud solutions. Leverage your expertise in FedRAMP and DoD IL4 to drive technical sales strategies and ensure compli...
3 weeks ago
$95K - $115K *
Unlock your potential as a Senior VDC Engineer, driving innovative design solutions and enhancing project delivery through advanced BIM technologies and collaboration with diverse teams in a dynamic e...
2 weeks ago
Idira Partner Architect | Remote, USA
$120K - $145K *
Explore a pivotal role as a Pre-Sales Partner Architect, driving technical enablement and strategic solutions. Collaborate with sales and partners to enhance client outcomes through expert presentatio...
2 weeks ago
Idira Partner Architect | Remote, USA
$120K - $145K *
Drive pre-sales excellence as a strategic technical advisor, enhancing client outcomes through solution demonstrations and enablement programs while collaborating across sales, services, and partner e...
2 weeks ago
Engineering Manager - Secure Access
$140K - $170K *
Advance your career by leading a dynamic team in developing secure access solutions. Drive technical direction, manage project delivery, and mentor engineers while balancing customer reliability with...
3 weeks ago
Data Center Power Generation and Microgrids Engineer
$320K - $405K *
Innovate the future of data center power generation and microgrids. Own the architecture for on-site generation and storage systems, ensuring reliable energy solutions that meet demanding load profile...
4 days ago
$100K - $120K *
Champion project success by leading on-site teams and coordinating construction activities, ensuring compliance with safety standards and efficiency goals while fostering positive relationships with s...
Reposted 2 weeks ago
$139K - $219K *
Empower client relationships by serving as the primary contact for the US Navy, anticipating needs and driving business growth through strategic marketing and data analysis while maintaining accurate...
Today
Business Development Manager- Data Centers Midwest
$80K - $100K *
Lead the charge in developing high-performance building specifications for Data Center projects. Engage with key influencers and coordinate with sales teams to drive growth and enhance product selecti...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.