Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Oracle Principal Pre-Sales & Delivery Architect
$150K - $180K *
Unlock the potential of Oracle solutions by leading multi-engagement pre-sales and delivery efforts. Drive customer adoption and value through strategic solution design, ensuring seamless integration...
1 week ago
Business Development Manager - Hyperscalers & Colocation
$108K - $181K *
Partner with us to drive growth in the data center market by building strategic relationships with hyperscalers and colocation providers, shaping innovative solutions, and leading negotiations to secu...
1 week ago
$120K - $145K *
Elevate security standards by leading bug bounty programs, conducting audits, and enhancing software supply chain security. Collaborate across teams to build innovative tools that protect users and en...
1 week ago
Director of Cloud Team - Remote
$128K - $225K *
Unlock potential by leading cloud engineering strategy and product development. Oversee a high-performing team to deliver secure, scalable cloud solutions across multiple providers, ensuring alignment...
1 week ago
$160K - $180K *
Join us to lead our accounting operations, ensuring accuracy and scalability. Drive financial reporting, audits, and team development while applying your technical expertise in a dynamic, multi-channe...
3 weeks ago
$125K - $150K *
Transform business workflows by developing and maintaining applications that enhance productivity and information sharing across teams. Collaborate with IT and business units to deliver innovative sol...
Reposted yesterday
$90K - $110K *
Join a dynamic team as you drive growth by designing tailored software solutions for schools. Leverage your technical expertise to engage clients, deliver impactful demos, and collaborate with cross-f...
Reposted 3 weeks ago
$119K - $179K *
Support the integration and harmonization of clinical data by designing FHIR-compliant models and pipelines, ensuring data accuracy and usability for patient care and research initiatives across the o...
3 weeks ago
$80K - $95K *
Drive enterprise IT infrastructure and security initiatives, optimizing cloud and networking environments while mentoring support staff and leading technology upgrades to enhance organizational perfor...
2 weeks ago
$115K *
Join a team that's dedicated to driving sales success through lead generation and client education. This role involves delivering impactful product demonstrations and collaborating with sales teams to...
Today
$145K - $175K *
Advance your career by overseeing Oracle system integrations across multiple customer engagements. Collaborate with teams to enhance platform ownership and provide pre-sales support, ensuring seamless...
2 weeks ago
Manager, Cloud Security Engineering
$125K - $150K *
Lead the charge in cloud security engineering by managing a team of experts to design and implement robust security controls across AWS, Azure, and GCP, ensuring compliance and operational excellence...
5 days ago
$160K - $185K *
Join us to lead a dynamic team of DevOps, MLOps, and DataOps engineers, driving innovation across our multi-cloud platform. You'll mentor talent, set technical standards, and remain hands-on in engine...
3 weeks ago
Lead Electrical CAD Engineer - Data Center Infrastructure
$105K - $189K *
Engineer innovative electrical designs, ensuring compliance and safety for mission-critical power and cooling products. Collaborate cross-functionally to integrate systems, manage changes, and execute...
Reposted 2 weeks ago
$90K - $125K *
Join a team that's dedicated to building robust software solutions. Collaborate with cross-functional teams to design, develop, and maintain high-quality applications while ensuring reliability and pe...
1 week ago
Senior Solutions Executive - Networking
$68K - $99K *
Unlock potential by driving sales of Hybrid Infrastructure services, expanding market presence, and managing the full sales lifecycle. Build relationships, identify opportunities, and collaborate with...
Today
Director, Solutions Architecture
$160K - $180K *
Lead a high-performing team of Solutions Architects to drive strategic market expansion and enhance presales execution. Collaborate across functions to ensure alignment and deliver impactful solutions...
Today
Modern Work Architect (Remote in USA)
$135K - $160K *
Drive the architecture and delivery of AI-ready Microsoft 365 solutions, overseeing end-to-end engagements for mid-market and enterprise clients. Lead design, deployment, and adoption while ensuring s...
1 week ago
Solution Architect - ArcGIS Enterprise (Defense & Intelligence)
$120K - $197K *
Transform geospatial solutions by architecting and integrating enterprise ArcGIS systems for Defense and Intelligence operations, ensuring secure, scalable architectures that enhance decision-making a...
Today
Staff Cyber Security Architect
$111K - $186K *
Optimize security architecture for cloud and on-premise systems. Collaborate with teams to ensure secure designs, conduct risk assessments, and develop reusable guidance. Leverage your cybersecurity e...
4 days ago
$171K - $190K *
Unlock potential by leading the design and implementation of scalable data platforms. Drive innovation in cloud data architecture and pipeline automation, collaborating across teams to deliver impactf...
3 weeks ago
SAP Principal Delivery Architect
$150K - $180K *
Transform customer engagements by owning solution direction across multiple accounts. Drive platform adoption, orchestrate delivery teams, and shape opportunities to ensure measurable value and long-t...
4 weeks ago
Cloud Native Architect, Portworx
$135K - $160K *
Empower your career by leading the charge in Kubernetes innovation. As a Cloud Native Architect, you'll leverage your expertise to transform customer experiences and drive the adoption of stateful app...
Today
Pre-Sales Solutions Engineer, HCM
$95K - $125K *
Join a team that's transforming HR and payroll solutions by engaging clients, conducting tailored demos, and bridging business needs with technical expertise to enhance workforce management and compli...
5 days ago
$95K - $115K *
Transform the future of power management by architecting data solutions that integrate telemetry, financials, and operational insights into a cohesive digital twin, enhancing decision-making across th...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.