Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$163K - $245K *

Support the sales team by providing technical expertise and solutions for F5 products. Engage with customers to understand their needs, drive sales processes, and deliver world-class service while ach...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$133K - $200K *

Inspire technical excellence by supporting sales teams with F5 solutions, driving customer engagement, and delivering tailored presentations. Collaborate with internal resources to achieve sales targe...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$281K - $449K *

Unlock growth in the Cloud & AI semiconductor market by leading direct and indirect sales strategies. Collaborate with cross-functional teams to drive adoption of interconnect solutions and engage wit...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Unlock potential by designing and implementing enterprise identity solutions, ensuring secure access across cloud and hybrid environments while collaborating with cross-functional teams to enhance IAM...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $150K *

Accelerate customer success by forging strategic partnerships and guiding enterprise clients through their AI security journeys, ensuring they achieve measurable outcomes and realize business value fr...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Elevate network operations by leading complex incident responses and mentoring teams. Collaborate with cross-functional partners to enhance network reliability and operational maturity across global e...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$100K - $125K *

Lead innovative design solutions as a Senior Design Engineer, transforming client needs into actionable broadcast system designs. Collaborate with global teams, mentor junior engineers, and ensure pro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$73K - $87K *

Unlock potential by driving transformation through emerging technologies. Collaborate with stakeholders to analyze, prototype, and implement AI solutions that address real-world challenges, ensuring h...

2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$95K - $115K *

Shape the future of cloud solutions by designing and deploying Azure services, ensuring security and scalability while automating workflows and providing technical support for cloud infrastructure and...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Join a team that's redefining cloud solutions by designing and deploying Azure services, ensuring security and scalability while automating workflows and enhancing performance through innovative techn...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$121K - $206K *

Lead the charge in architecting and delivering Microsoft Azure and 365 solutions for SMBs. Oversee cloud migrations, security implementations, and project management while fostering strong partner rel...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Develop and enhance core infrastructure platforms, ensuring operational excellence and security. Collaborate with cross-functional teams to maintain reliable services, support disaster recovery, and d...

1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$80K - $95K *

Join a dynamic team to enhance and secure core infrastructure platforms, focusing on virtualization, cloud services, and disaster recovery. Collaborate with cross-functional teams to ensure operationa...

1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$160K - $180K *

Lead the design and implementation of warehouse solutions, guiding teams through the Tecsys Elite WMS architecture. Drive integration, configuration, and continuous improvement while ensuring operatio...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$73K - $218K *

Lead the charge in designing innovative digital solutions that enhance operational performance and customer experience. Collaborate across teams to translate complex business challenges into scalable...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$80K - $100K *

Unlock your potential by contributing to enterprise EDI and integration projects. Collaborate with experienced engineers to design, implement, and optimize solutions, enhancing customer satisfaction a...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Advance the future of financial engineering by building a robust platform for pricing, billing, and revenue management in an AI-driven environment. Collaborate cross-functionally to automate processes...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$97K - $143K *

Manage complex electrical and industrial construction projects from kickoff to closeout, ensuring safe, efficient execution while collaborating with customers, subcontractors, and internal teams to de...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$97K - $143K *

Lead complex electrical and industrial construction projects, ensuring safe, efficient execution from kickoff to closeout while collaborating with diverse teams and stakeholders to deliver critical in...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a dynamic team to design and optimize enterprise infrastructure, leading initiatives in network architecture, virtualization, and cloud services while ensuring reliability and security across sys...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$146K - $234K *

Transform complex challenges into innovative solutions by leveraging expertise in RF communications, machine learning, and data analytics to enhance cybersecurity and network research for government a...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$200K - $250K *

Join us in shaping technical strategies and growth initiatives for federal opportunities. Collaborate across teams to develop compelling solutions that drive success in complex pursuits, ensuring alig...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Advance your career by leading complex architectural projects, ensuring design excellence and regulatory compliance while mentoring a talented team and collaborating across disciplines to deliver inno...

4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$99K - $232K *

Lead the charge in transforming P&C insurance operations by guiding teams, enhancing service delivery, and implementing technology solutions to streamline processes and improve client engagement acros...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$99K - $232K *

Analyze and enhance service operations in the P&C insurance sector. Lead teams in technology solution design, streamline processes, and mentor staff to improve client engagements and service delivery...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.