Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$74K - $87K *

Join us to enhance network performance by providing expert support for Layer 2 provisioning, troubleshooting, and testing. Collaborate with teams to ensure seamless operations and customer satisfactio...

6 days ago

  •   Less than 5 years exp.  •   Transportation

$74K - $87K *

Elevate your career by providing expert support for SEGRA Networks. As a Network Provisioning Engineer II, you'll leverage your skills in Layer 2 provisioning, ensuring seamless operations and custome...

6 days ago

  •   Less than 5 years exp.  •   Transportation

$100K - $145K *

Join a dynamic team to ensure seamless network connectivity for dock deployments. Collaborate with IT teams, troubleshoot connectivity issues, and enhance customer confidence through effective communi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$320K - $405K *

Engineer cutting-edge protection and automation systems for high-voltage substations, ensuring reliable power distribution and integration across our infrastructure portfolio. Collaborate with teams t...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $165K *

Join a dynamic team to design and implement robust cloud security solutions across diverse environments, ensuring safe adoption of AI and compliance with regulatory standards while leading technical i...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $95K *

Join a dynamic Infrastructure team to design, implement, and manage secure, reliable networks. Enhance connectivity and performance across local and wide area networks while troubleshooting and optimi...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Elevate your career by partnering with us to optimize enterprise network performance. You'll troubleshoot complex issues, collaborate with cross-functional teams, and drive improvements to ensure secu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$87K - $253K *

Empower enterprise data initiatives by providing architectural leadership and governance. Guide teams in best practices for scalable data solutions, ensuring quality and compliance while fostering inn...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$135K - $160K *

Advance security integration by leading DevSecOps initiatives, enhancing software delivery, and establishing robust security standards across engineering teams to mitigate risks and improve efficiency...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Empower innovation as you design complex electrical systems, lead projects, mentor teams, and ensure high-quality deliverables. Collaborate closely with multi-disciplinary teams, utilizing advanced BI...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Oversee complex electrical design projects and deliver fully constructible BIM models. Collaborate with cross-functional teams, mentor peers, and ensure compliance with safety standards while developi...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$156K - $281K *

Drive innovative solutions by leading complex Federal acquisitions, guiding cross-functional teams, and delivering high-quality proposals. Leverage technical expertise to elevate win probability and e...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$95K - $130K *

Manage the design and implementation of integrated physical security systems, driving innovative solutions in complex environments while fostering collaboration with clients and stakeholders for enhan...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$86K - $102K *

Take ownership of network operations and OSS functions, providing in-depth support and expertise. Collaborate with teams to design, develop, and implement network components, ensuring efficient projec...

6 days ago

  •   Less than 5 years exp.  •   Transportation

$86K - $102K *

Manage and support Transport, Packet, and Management Networks while designing, developing, and implementing network components. Collaborate with teams to ensure operational excellence and project succ...

6 days ago

  •   Less than 5 years exp.  •   Transportation

$130K - $155K *

Take ownership of the DevOps architecture, setting standards and strategies for infrastructure and delivery pipelines across multiple software solutions, while collaborating with software architects t...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Shape the future of security by leading cross-functional initiatives to enhance incident detection and response capabilities. Collaborate with diverse teams to identify risks, develop automation, and...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$105K - $167K *

Lead the charge in designing and optimizing AI platform architectures, ensuring reliability and performance at enterprise scale. Collaborate with cross-functional teams to implement best practices and...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$140K - $175K *

Develop innovative software solutions that enhance access to mental and physical health services. Collaborate with cross-functional teams to deliver reliable applications, ensuring quality and perform...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$107K - $150K *

Transform the security landscape by implementing and supporting cutting-edge physical security systems, ensuring client satisfaction and seamless integration for improved safety and network efficiency...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Transform the architecture of diverse security platforms, guiding teams through complex design challenges while ensuring scalable, secure, and maintainable systems across multiple product areas in a h...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $120K *

Elevate your career by leading clients through the CMMC 2.0 compliance journey. As a key advisor, you'll translate complex regulations into actionable strategies, ensuring audit readiness and security...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Innovate enterprise architecture solutions that enhance business operations. Collaborate with IT and business teams to tackle complex challenges, ensuring scalable, secure, and efficient systems acros...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $185K *

Unlock business growth by leading technical scoping, managing client relations, and guiding consultants. This hybrid role integrates project management with hands-on consulting to ensure accurate prop...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$244K - $409K *

Drive the development of a global SME organization, leading regional teams to enhance technical selling and product direction. Transform ambiguity into structure while mentoring leaders and collaborat...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.