Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$85K - $135K *

Lead the integration and evaluation of utility-scale energy storage systems, focusing on battery technology. Collaborate with R&D and engineering teams to enhance product performance and ensure compli...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$180K - $220K *

Drive strategic growth and client leadership in the Science and Tech market, leading high-performance teams to implement business plans and enhance brand presence while fostering innovative solutions...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Real Estate & Construction

$83K - $104K *

Empower your career by collaborating on innovative electrical designs for mission-critical facilities. Engage with senior engineers, enhance your skills, and contribute to impactful projects while wor...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Technical Services

$122K - $187K *

Grow your career by driving strategic sales initiatives within key accounts. Collaborate with C-suite executives to deliver tailored technology solutions, ensuring exceptional customer experiences whi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$108K - $130K *

Elevate your career by managing Computer System Assurance projects, ensuring compliance with global regulations and quality standards. Lead teams to develop validation strategies that guarantee data i...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Elevate cybersecurity solutions by driving revenue growth through strategic sales, managing the full sales lifecycle, and building strong relationships with clients and partners to enhance market pres...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Join a dynamic team to enhance operational workflows for autonomous trucking. Lead process design, maintain quality standards, and drive continuous improvement across multiple workstreams while collab...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Drive innovation by designing async backend systems that integrate AI seamlessly, enabling scalable solutions for millions of businesses. Collaborate with a dynamic team to transform concepts into pro...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$200K - $225K *

Transform the future of cloud commerce by leading the design and evolution of scalable, resilient systems that enhance platform reliability and drive innovation across teams and products...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$83K *

Transform the candidate experience by coordinating interviews and managing communications. Collaborate with recruiters and hiring managers to streamline processes, ensuring efficiency and excellence i...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive strategic insights by analyzing cross-functional data to enhance decision-making. Collaborate with teams to build a trusted business intelligence framework, delivering actionable recommendations...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Empower business success by collaborating with cross-functional teams to enhance operations, gather requirements, and implement IT solutions that align with strategic goals. Drive improvements in orde...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to enhancing technical enablement for sales and engineering roles. You'll develop scalable training programs, manage onboarding, and create hands-on resources to ensure fl...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Empower your career by leading security engineering initiatives across product, cloud, and AI domains. Drive security architecture, vulnerability management, and team growth while ensuring robust secu...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$85K - $90K *

Drive impactful analytics solutions by leading customer engagement workstreams, optimizing digital communications, and mentoring junior analysts. Leverage data to enhance government program performanc...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $158K *

Champion high-availability database platforms, driving automation and cloud modernization. Collaborate with engineering teams to enhance reliability and performance across hybrid environments, ensurin...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$111K - $197K *

Champion integration solutions by leading projects, conducting discovery sessions, and implementing complex integrations for clients in Higher Education and Nonprofit sectors. Drive results and ensure...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $145K *

Empower the development of high-quality web interfaces by leading projects, mentoring engineers, and enhancing engineering processes. Collaborate on technical vision while fostering a culture of excel...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Empower your career by managing diverse Cybersecurity projects from initiation to completion. Collaborate with teams, engage clients, and ensure project success through effective planning and executio...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Elevate your career by leading SCADA design and engineering for high-voltage electrical power systems. Collaborate with a multi-disciplinary team to optimize substation projects, ensuring efficient ex...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$95K - $115K *

Elevate your career by driving the design and deployment of AVEVA MES projects. Collaborate with cross-functional teams to ensure quality solutions, mentor junior engineers, and enhance user adoption...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $214K *

Lead the charge in designing and implementing enterprise Finance solutions, optimizing processes, and driving global transformation initiatives through innovative technology and collaboration with sta...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$185K - $260K *

Champion security excellence by designing and implementing robust software solutions. Collaborate with teams to enhance security practices, conduct code reviews, and respond to incidents, ensuring a s...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$73K - $102K *

Transform ERP solutions by customizing modules, integrating features, and ensuring compliance. Collaborate with stakeholders to gather requirements and enhance system performance while maintaining doc...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$192K - $240K *

Empower innovation as you lead complex AI system design and delivery, influencing architecture and engineering practices. Collaborate across teams to ensure scalable, high-quality solutions with signi...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.