Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$160K - $180K *

Shape the demand generation strategy for the MSP segment, leading a high-impact team to optimize funnel performance and drive revenue growth through innovative marketing approaches and AI tools...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$157K - $185K *

Join as a Principal Data Engineer to tackle complex data challenges. Lead the design and implementation of scalable data architectures while mentoring teams and establishing engineering standards acro...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$183K - $190K *

Unlock your potential by leading SAP GTS projects, designing solutions, and driving customer success. Collaborate with teams to deliver innovative implementations and enhance business processes while...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $131K *

Transform IT business processes through analysis and automation, enhancing efficiency and compliance. Leverage tools like Microsoft Power Platform and ServiceNow to align technology with strategic goa...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$78K - $126K *

Unlock potential by providing expert compliance advisory services to diverse organizations. Collaborate with clients to enhance grant management, internal controls, and operational effectiveness throu...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$100K - $125K *

Optimize game development by enhancing build systems and automating infrastructure. Collaborate with teams to ensure reliable deployments across multiple platforms, driving efficiency and innovation i...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$135K - $160K *

Join a team that's shaping developer experiences by creating impactful tutorials, demo apps, and tools. Collaborate across departments to enhance adoption and usability of Render's products while test...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $100K *

Join a team that's dedicated to ensuring sales compensation accuracy and integrity. You'll support deal desk operations and provide analytical insights, making a significant impact on revenue processe...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$466K - $500K+*

Unlock potential by developing scalable AI/ML model serving infrastructure. Collaborate cross-functionally to enhance performance and availability of high-traffic systems, driving innovation in a dyna...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$183K - $220K *

Elevate technical storytelling by creating impactful demos and workshops that bridge the gap between product capabilities and customer understanding, empowering sales teams and enhancing buyer engagem...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Lead a dynamic team focused on expanding government business opportunities. Drive strategic account development, foster relationships, and create demand for modular solutions across federal, state, an...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$115K - $135K *

Empower progress at the forefront of cybersecurity by managing security operations, ensuring compliance, and mitigating risks. Collaborate with teams to enhance security measures and protect sensitive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$132K - $220K *

Join a team that's driving innovation in cloud technology and engineering excellence. Lead and mentor engineers while shaping strategic direction for Fan and Club products, ensuring high performance a...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$140K - $185K *

Drive technical excellence by developing standards and processes for commissioning, ensuring consistent execution across projects. Collaborate with cross-functional teams to enhance workforce capabili...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Join a team that's dedicated to delivering expert engineering solutions while managing projects safely and efficiently. Leverage your technical expertise to mentor others and drive innovation in gener...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$184K - $356K *

Unlock potential by developing innovative AI solutions and enhancing infrastructure capabilities. Collaborate with strategic partners to deliver hands-on technical support, ensuring optimal performanc...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Drive growth by managing strategic enterprise accounts, navigating complex sales cycles, and building consensus among security-focused buying committees to secure multi-year contracts in a competitive...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Transform enterprise data architecture through expert Azure platform engineering, enhancing reliability, governance, and cost-efficiency while collaborating with cross-functional teams to optimize dat...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Unlock your potential by supporting complex customer needs through expert solution design and seamless sales transitions. Collaborate with teams to drive sales opportunities and enhance customer engag...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $215K *

Unlock the potential of technical enablement by managing global projects, developing engaging content, and collaborating with teams to enhance enterprise security solutions and drive go-to-market succ...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Drive your career with a pivotal role managing technical partnerships, scoping integrations, and ensuring successful collaboration between engineering teams and partners. Shape strategic conversations...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Drive the development and support of healthcare interfaces and FHIR APIs, ensuring secure clinical data exchange. Collaborate with teams to implement solutions that enhance health information interope...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Take ownership of developing and supporting healthcare interfaces and FHIR APIs for a statewide Health Information Exchange, ensuring secure and reliable clinical data exchange across multiple healthc...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Empower your career by developing secure healthcare interfaces and FHIR APIs. Collaborate on a statewide Health Information Exchange, ensuring reliable clinical data exchange while supporting diverse...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Partner with us to deliver tailored solutions and in-depth demos, supporting a dynamic sales pipeline. Leverage your technical expertise to drive customer success and collaborate with teams to enhance...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.