Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$57K - $117K *

Pioneer innovative training solutions as a UPK Developer, enhancing the Marine Corps ERP logistics system by creating engaging training materials and simulations. Collaborate with a dedicated team to...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$91K - $138K *

Contribute to our growth by driving sales of SaaS solutions to government agencies. Collaborate with partners, build relationships, and exceed sales targets while navigating the complexities of govern...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$170K - $185K *

Champion the development of scalable data platforms, leading cross-functional initiatives and enhancing AI-assisted analytics. Collaborate with teams to drive technical direction and improve system pe...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$95K - $115K *

Champion cybersecurity excellence by leading initiatives to protect sensitive healthcare data. Collaborate with IT and clinical teams to ensure compliance and implement robust security measures, while...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $200K *

Advance partner success by optimizing enablement strategies and driving revenue growth through data-driven insights and strategic program management in a collaborative environment...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $160K *

Accelerate product development by managing the software lifecycle, collaborating with cross-functional teams, and driving strategic initiatives to enhance user experience and meet stakeholder needs...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $190K *

Lead the charge in managing the software development lifecycle for innovative products, leveraging low-code platforms to enhance user experience and drive strategic initiatives across cross-functional...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$90K - $110K *

Transform project delivery by leading software implementations, ensuring timely and budget-friendly outcomes while fostering strong stakeholder relationships and navigating complex environments with c...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Elevate developer engagement by representing Render at events, crafting workshops, and shaping technical direction. Drive community feedback into product enhancements while building strong relationshi...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Transform client relationships by leading a dynamic team to achieve financial growth and enhance client experiences across a diverse portfolio. Drive strategic initiatives and foster collaboration to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $195K *

Transform enterprise sales by engaging CIOs and CTOs, leading complex sales cycles, and connecting technology strategies to measurable business outcomes. Collaborate with cross-functional teams to dri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$182K - $273K *

Champion innovative power architecture solutions, driving analysis and optimization across CPU, AI, and SoC designs. Collaborate with cross-functional teams to enhance power management and validate pe...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$101K - $140K *

Drive the evolution of Business Systems by integrating automation and AI into our go-to-market processes. Collaborate with cross-functional teams to build scalable systems that enhance efficiency and...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$191K - $293K *

Explore the future of security by leading vulnerability research efforts, enhancing software defenses, and streamlining remediation processes to protect critical networks from emerging threats...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$159K - $235K *

Optimize security infrastructure by designing and implementing robust access management and secrets storage solutions, ensuring seamless integration and operational excellence across engineering teams...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Lead the charge in building critical infrastructure with a self-performing team. Oversee structural installations, ensure safety and quality standards, and manage project schedules across multiple sit...

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$82K - $123K *

Join a dynamic team to design, develop, and maintain robust integrations using Oracle SOA and WebMethods, enhancing operational performance and delivering high-quality solutions in a collaborative env...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $95K *

Unlock potential by managing Genesys Cloud configurations and ensuring system integrity. Collaborate with teams to implement changes, troubleshoot issues, and maintain documentation for optimal contac...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$180K - $240K *

Unlock innovative solutions as you build full-stack applications for federal partners, focusing on user experience, security, and seamless integrations. Collaborate with engineers and product teams to...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$240K - $318K *

Lead a global BSS engineering team, driving architecture, delivery, and product strategy while ensuring platform performance and compliance across diverse telecommunications solutions...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$100K - $120K *

Transform the sales process by providing expert technical support and product demonstrations. Collaborate with internal teams to address customer needs and enhance training, ensuring a seamless experi...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$97K - $145K *

Join a team that's dedicated to ensuring accurate coding and compliance for clinical services, leveraging your expertise to enhance revenue cycle management and contribute to optimal healthcare outcom...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$67K - $100K *

Drive operational excellence by supporting the development and maintenance of standardized playbooks, SOPs, and workflows. Collaborate with cross-functional teams to ensure clarity and consistency in...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$80K - $95K *

Deliver exceptional customer experiences by fostering relationships, guiding onboarding, and ensuring success metrics are met. Play a key role in customer retention and expansion while advocating for...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$63K - $129K *

Transform security operations by automating ICAM workflows and enhancing Zero Trust policies. Collaborate with cross-functional teams to build secure, scalable solutions that strengthen enterprise sec...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.