Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$62K - $125K *

Transform the sales landscape by building your own pipeline through relentless prospecting and effective demos. Collaborate with leadership to refine strategies and drive growth in a dynamic startup e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$220K - $275K *

Partner with us to drive AI transformation in customer experience. As a Principal Solutions Engineer, you'll guide clients through the design and implementation of innovative AI solutions, ensuring al...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $155K *

Join a team that's shaping the future of data services by designing and implementing robust integration solutions. Leverage your expertise in Ruby on Rails and REST APIs to drive innovative projects a...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$120K - $140K *

Shape the future of federal financial operations by driving user adoption and change management for a new tool. Collaborate with stakeholders to enhance user experience, streamline processes, and ensu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $158K *

Champion quality assurance by collaborating in Agile teams to deliver robust software solutions. Leverage your testing expertise to enhance product quality and drive continuous improvement in a dynami...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $140K *

Elevate your career by joining a dynamic team to design and implement innovative cloud solutions in a multi-cloud environment, ensuring scalability, security, and alignment with business objectives wh...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$172K - $229K *

Build and lead a team to enhance platform testing and support for core infrastructure. Drive technical direction, manage incident response, and ensure software quality across systems, while collaborat...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Transportation

$120K - $145K *

Unlock your potential as a technical leader driving enterprise identity and messaging services. Manage a talented team of engineers, ensuring reliable operations and security in a hybrid environment w...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Information Technology

$315K - $370K *

Join a team that's redefining offensive security by leading engineering efforts to transform research into scalable, customer-facing products. Drive strategy, execution, and innovation across multiple...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$92K - $115K *

Transform client data integration processes by designing, building, and testing seamless connections between systems. Collaborate with teams to ensure optimal performance and security while delivering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$170K - $200K *

Transform client relationships by leading data-driven solutions for major tech firms. Engage with executives to uncover insights, drive impactful decisions, and ensure seamless delivery across teams i...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$111K - $150K *

Elevate your career by leading the design and integration of advanced electrical control systems. Collaborate with engineering teams to enhance efficiency and mentor junior members while ensuring proj...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$230K - $345K *

Lead the charge in database excellence to enhance reliability, performance, and sustainability of GitLab's datastores. Shape long-range strategies while collaborating across teams to drive success in...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$106K - $115K *

Unlock your potential as you contribute to scalable software solutions, collaborating with cross-functional teams to enhance assessment systems. Gain hands-on experience in modern development practice...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$88K - $154K *

Transform your career by leading full-lifecycle recruiting for federal proposals, focusing on defense and intelligence sectors. Collaborate with teams to develop strategies, source talent, and ensure...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Unlock potential by leading IT SOX compliance and enhancing global security culture. Balance technical auditing with advocacy, ensuring financial integrity and regulatory adherence while fostering a r...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$215K - $255K *

Grow your career by leading the evolution of a dynamic training program for early-career Solutions Engineers, ensuring high-quality learning experiences and effective deployment into the field while f...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Empower teams by designing and building scalable, secure systems that enhance performance and reliability. Collaborate across disciplines to innovate with AI while maintaining a security-first approac...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$95K - $115K *

Engage in a dynamic role overseeing large projects and teams, ensuring successful delivery through effective stakeholder coordination and project management. Contribute to innovative power delivery so...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Unlock your potential as a Senior DevSecOps Engineer, driving operational excellence in Linux and DB2 administration. Collaborate across teams to enhance application performance and security in a full...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$99K - $115K *

Lead the charge in designing and coordinating mechanical systems for diverse projects. Ensure compliance, constructability, and alignment with client goals while managing documentation and client comm...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Technical Services

$135K - $160K *

Drive your career forward by developing cutting-edge control planes for AI infrastructure. Collaborate with a dynamic team to enhance cloud-native orchestration platforms, leveraging your expertise in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Lead the charge in shaping and expanding bridge design services across New England. Provide strategic direction, oversee project delivery, mentor staff, and strengthen client relationships to enhance...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$120K - $145K *

Drive mobile engineering excellence by leading app development, mentoring engineers, and integrating AI solutions to enhance user experiences across iOS and Android platforms while collaborating with...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$57K - $117K *

Pioneer innovative training solutions as a UPK Developer, enhancing the Marine Corps ERP logistics system by creating engaging training materials and simulations. Collaborate with a dedicated team to...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.